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Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update
Important developments that are addressed by the current update include the antiemetic efficacy of olanzapine; evidence to expand the use of NK1 receptor antagonists; and increasing interest in cannabinoids. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 2, 2017 Category: Consumer Health News Source Type: news

Antipsychotic Added to ASCO Antiemetic Guide
(MedPage Today) -- Olanzapine plus standard three-drug regimen (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - August 1, 2017 Category: Hematology Source Type: news

2016 Updated MASCC/ESMO consensus recommendations: Management of nausea and vomiting in advanced cancer
The aim of this paper was to develop a set of evidence-based guidelines for the management of different syndromes related to nausea and vomiting in advanced cancer. The authors found that the level of evidence in most studies is low, but conclude that the drug of choice is metoclopramide, with alternative options including haloperidol, levomepromazine, or olanzapine. For bowel obstruction, the recommendation is to use octreotide given alongside an antiemetic (haloperidol) and where octreotide is not an option to use an anticholinergic antisecretory agent. For opioid-induced nausea and vomiting, no recommendation could be m...
Source: Current Awareness Service for Health (CASH) - April 25, 2017 Category: Consumer Health News Source Type: news

Antipsychotic adjunctive therapy to mood stabiliser should be continued for 6months after remission of a manic episode
One hundred and seventy-eight patients from academic centres in Canada and Brazil with bipolar I disorder and aged ≥17 years, who recently remitted from an acute manic or mixed episode with a combination of mood stabiliser (lithium or valproate) and atypical antipsychotic (risperidone or olanzapine) were randomised to one of the three following groups: (1) discontinue risperidone or olanzapine over 2 weeks beg inning on the day of randomisation and receive placebo substitution for the remaining 50 weeks; (2) receive risperidone or olanzapine for 24 weeks, followed by tapering and discontinuation of the antipsychotic ove...
Source: Current Awareness Service for Health (CASH) - March 16, 2017 Category: Consumer Health News Source Type: news

Delpor Awarded NIH Grant for 3-month Olanzapine Implant for the...
The NIMH funds Delpor’s efforts to utilize its PROZOR™ technology in developing a matchstick-size subcutaneous implant device capable of delivering olanzapine for 3 months through passive diffusion....(PRWeb February 24, 2017)Read the full story at http://www.prweb.com/releases/2017/02/prweb14088705.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 24, 2017 Category: Pharmaceuticals Source Type: news

Symbyax (Olanzapine and fluoxetine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - January 23, 2017 Category: Drugs & Pharmacology Source Type: news

Patient with 108-Degree Fever Shows Seriousness of Early Recognition & Treatment of Hyperthermia
Medic 35 is dispatched to a local subdivision for an obese 62-year-old woman with syncope. The responding unit is a fire-based ALS unit staffed by two paramedics. Patient Assessment It's approximately 2:30 p.m., with outside temperatures reaching 95 degrees F and the humidity is at 65%.The patient is lying in the grass next to a picnic blanket and paper plates with half eaten sandwiches. Her husband crouches over her. He says his wife started to complain she felt unwell, and then passed out. Upon evaluation, she's unresponsive to sternal rub. Her airway is patent. Her breaths are rapid and shallow with rales bilaterally. H...
Source: JEMS Patient Care - November 1, 2016 Category: Emergency Medicine Authors: Christine M. Brent, MD Tags: Patient Care Source Type: news

Zyprexa, Zyprexa Zydis (Olanzapine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 8, 2016 Category: Drugs & Pharmacology Source Type: news

Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting
This study is highlighted by DynaMed Plus as a Practice Changing Update. It concludes that the addition of olanzapine 10 mg to 3-drug antiemetic regimen may reduce nausea in patients receiving highly emetogenic chemotherapy. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 22, 2016 Category: Consumer Health News Source Type: news

Sanford Health trial finds new treatment to stop vomiting in chemotherapy
A clinical researched co-authored by Sanford Health oncologist and cancer researcher Steven Powell has found that the drug olanzapine has potential to reduce chemotherapy-induced side effects such as nausea and vomiting. (Source: Drug Development Technology)
Source: Drug Development Technology - July 20, 2016 Category: Pharmaceuticals Source Type: news

Olanzapine Prevents Chemo-Induced Nausea
Adding the antipsychotic drug olanzapine to a standard antiemetic regimen significantly improved prevention of nausea caused by emetogenic chemotherapy. (Source: CancerNetwork)
Source: CancerNetwork - July 16, 2016 Category: Cancer & Oncology Authors: Anna Azvolinsky Tags: Nausea and Vomiting News Source Type: news

Zyprexa Prevents Chemo Nausea (CME/CE)
(MedPage Today) -- Randomized trial findings support previous studies (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - July 15, 2016 Category: Gastroenterology Source Type: news

Olanzapine for Prevention of Chemo-induced Nausea and VomitingOlanzapine for Prevention of Chemo-induced Nausea and Vomiting
Adding the antipsychotic to standard antiemetic therapy appears to greatly reduce vomiting and nausea in patients receiving highly emetogenic chemotherapy. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 13, 2016 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Olanzapine 'Really Makes a Difference' in CINVOlanzapine 'Really Makes a Difference' in CINV
Adding the antipsychotic to standard antiemetic therapy appears to greatly reduce vomiting and nausea in patients receiving highly emetogenic chemotherapy. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - July 13, 2016 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Antipsychotic drug also relieves nausea from cancer chemotherapy
(Reuters Health) - Adding the cheap antipsychotic drug olanzapine to conventional anti-vomiting medicine can help prevent nausea in cancer patients, according to a new test of 380 volunteers. (Source: Reuters: Health)
Source: Reuters: Health - July 13, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

La FDA advierte de reacciones de la piel poco comunes, pero graves con el uso del psicofármaco olanzapina (Zyprexa, Zyprexa Zydis, Zyprexa Relprevv y Symbyax)
[05-10-2016] La Administración de Alimentos y Medicamentos de los Estados Unidos (FDA, por sus siglas en inglés) advierte que el fármaco antipsicótico olanzapina puede causar una reacción cutánea poco común, pero grave, que puede avanzar y afectar otras partes del cuerpo. Estamos añadiendo una nueva advertencia a la etiqueta de información farmacológica de todos los productos que contienen olanzapina, la cual describe esta grave afección conocida como síndrome de hipersensibilidad a medicamentos con eosinofilia y síntomas sisté...
Source: FDA Center for Drug Evaluation and Research - What's New - June 7, 2016 Category: Drugs & Pharmacology Source Type: news

FDA: Olanzapine can cause serious skin reaction
Olanzapine can cause a rare but serious skin reaction that can affect other parts of the body, according to a Food and Drug Administration safety alert released May 10. The condition linked to all products containing the second-generation antipsychotic is called Drug Reaction with Eosinophilia and... (Source: Skin and Allergy News)
Source: Skin and Allergy News - May 11, 2016 Category: Dermatology Source Type: news

FDA: Olanzapine can cause serious skin reaction
Olanzapine can cause a rare but serious skin reaction that can affect other parts of the body, according to a Food and Drug Administration safety alert released May 10. The condition linked to all... (Source: Family Practice News)
Source: Family Practice News - May 11, 2016 Category: Primary Care Source Type: news

FDA Warns of Serious Skin Reaction with Antipsychotic Olanzapine (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM The atypical antipsychotic olanzapine (Zyprexa and others) can cause a serious skin reaction known as drug reaction … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - May 10, 2016 Category: Primary Care Source Type: news

FDA Drug Safety Communication: FDA warns about rare but serious skin reactions with mental health drug olanzapine (Zyprexa, Zyprexa Zydis, Zyprexa Relprevv, and Symbyax)
[05-09-2016] The U.S. Food and Drug Administration (FDA) is warning that the antipsychotic drug olanzapine can cause a rare but serious skin reaction that can progress to affect other parts of the body. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - May 10, 2016 Category: Drugs & Pharmacology Source Type: news

FDA Warns of Skin Reaction With Olanzapine
(MedPage Today) -- Zyprexa and Symbyax among products to get warning label (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - May 10, 2016 Category: Primary Care Source Type: news

Olanzapine Linked to Rare but Serious Skin Reaction, FDA WarnsOlanzapine Linked to Rare but Serious Skin Reaction, FDA Warns
The US Food and Drug Administration is warning that the antipsychotic olanzapine has been linked to a rare but potentially life-threatening skin condition. News Alerts (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 10, 2016 Category: Consumer Health News Tags: Psychiatry News Alert Source Type: news

A Major Advance Against Chemotherapy's Most Feared Side EffectA Major Advance Against Chemotherapy's Most Feared Side Effect
Dr Mark Kris discusses a study showing that olanzapine is safe and effective for chemotherapy-induced nausea and emesis. Medscape Oncology (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - April 14, 2016 Category: Cancer & Oncology Tags: Hematology-Oncology Commentary Source Type: news

The Truth About Gay Men and Depression
It's time to reveal the truth and I'm just going to say it: gay men and depression coexist. Dark, unfathomable, or uneasy, it's just the truth. I realized I was depressed when I was 12 years old. My parents had divorced, I had trouble making friends at school and my mood felt as heavy as the fog that lays over the city of San Francisco where I grew up. I didn't want to get out of bed and life seemed entirely different than the happy childhood I once knew. Life before depression was idealistic. I enjoyed creative arts and running. I also had big dreams to become an actor in New York City. My friends knew me as the outgoing,...
Source: Healthy Living - The Huffington Post - March 17, 2016 Category: Consumer Health News Source Type: news

Acute poisoning with dapsone and olanzapine: severe methemoglobinemia and coma with a favourable outcome - Iliev YT, Zagorov MY, Grudeva-Popova JG.
Dapsone is a drug commonly used in the treatment of leprosy. In Europe it is rarely prescribed, mostly for the treatment of skin diseases such as dermatitis herpetiformis. Poisoning with dapsone is rare and reports of such cases are of interest for toxicol... (Source: SafetyLit)
Source: SafetyLit - March 11, 2016 Category: Global & Universal Tags: Home and Consumer Product Safety Source Type: news

Improving symptoms and side effects in older patients with schizophrenia with decreasing dopamine D2/3 receptor occupancy following resperidone and olanzapine dose reduction
The use of lower doses of antipsychotics is recommended by experts in the treatment of older patients with schizophrenia, with the literature suggesting that older age is related to greater antipsychotic sensitivity.1 To date, three randomised controlled trials have examined the effects of olanzapine and risperidone dose reduction on clinical outcome in schizophrenia with inconsistent results.2–4 However, this topic has not been addressed specifically in older patients with schizophrenia, nor has the relationship between decreased dopamine D receptor occupancy and cl...
Source: Current Awareness Service for Health (CASH) - March 3, 2016 Category: Consumer Health News Source Type: news

Zyprexa: Also a Pain Med?
(MedPage Today) -- Meta-analysis suggests analgesic effect for antipsychotic drug (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - February 22, 2016 Category: Psychiatry Source Type: news

Adding an Antipsychotic Helps Treat PainAdding an Antipsychotic Helps Treat Pain
A literature review finds that the atypical antipsychotic olanzapine has the most evidence supporting its use in various pain syndromes. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - February 19, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Understanding & Giving Support to Someone with Schizophrenia
What comes to mind when the word schizophrenia is spoken? Likely images of a bedraggled man or woman, with wild hair and tattered clothing, chatting away with someone that you can’t see, as they amble down a city street. You might actually cross the street to avoid him or her, so as not to get caught up in their delusion. The Diagnostic and Statistical Manual of Mental Disorders (DSM-V) describes the condition as “characterized by delusions, hallucinations, disorganized speech and behavior, and other symptoms that cause social or occupational dysfunction. For a diagnosis, symptoms must have been present for six...
Source: Psych Central - February 1, 2016 Category: Psychiatry Authors: Edie Weinstein, MSW, LSW Tags: Antipsychotics Atypical Antipsychotics Caregivers Disorders Family General Medications Psychology Psychotherapy Schizophrenia Treatment American Psychiatric Association Delusion Delusional disorder Diagnostic And Statistical Ma Source Type: news

Comunicado de la FDA sobre la seguridad de los medicamentos: La FDA investiga dos muertes tras inyección con antipsicótico de larga duración Zyprexa Relprevv (pamoato de olanzapina)
El 18 de junio, 2013, La Administración de Alimentos y Medicamentos de Estados Unidos (FDA por sus siglas en inglés) está investigando la inexplicable muerte de dos pacientes que recibieron una inyección intramuscular del medicamento antipsicótico Zyprexa Relprevv (pamoato de olanzapina). (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 19, 2016 Category: Drugs & Pharmacology Source Type: news

Transforming Pharmaceutical Manufacturing: Benefits and Challenges
Guest Editor(s) Robin Bogner and Ajaz Hussain Investigations of the effect of the lipid matrix on drug entrapment, in vitro release, and physical stability of olanzapine loaded solid lipid nanoparticles Author(s) K. Vivek Harivardhan Reddy Ramachandra S. R. Murthy (Source: AAPS Publications)
Source: AAPS Publications - August 19, 2015 Category: Drugs & Pharmacology Source Type: news

Schizophrenia Treatment
Table of Contents Introduction Psychotherapy Medications Coping Guidelines For The Family Self-Help Introduction Schizophrenia usually first appears in a person during their late teens or throughout their twenties. It affects more men than women, and is considered a life-long condition which rarely is "cured," but rather treated. The primary treatment for schizophrenia and similar thought disorders is medication. Unfortunately, compliance with a medication regimen is often one of the largest problems associated with the ongoing treatment of schizophrenia. Because people who live with this disorder ofte...
Source: Psych Central - June 11, 2015 Category: Psychiatry Authors: John M. Grohol, Psy.D. Tags: Atypical Antipsychotics Disorders General Medications Schizophrenia Treatment how is schizophrenia treated medications for schizophrenia schizophrenia medications Schizophrenia Treatment Treatment For Schizophrenia Source Type: news

Novel Schizophrenia Drug Continues to Show PromiseNovel Schizophrenia Drug Continues to Show Promise
A novel, potent mu-opioid antagonist with olanzapine is designed to attenuate olanzapine-induced metabolic side effects. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 6, 2015 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Non-controlled and over-the-counter drugs of abuse
  2.5 out of 5 stars Abuse of Medications That Theoretically Are Without Abuse Potential. Reeves RR et al. South Med J 2015 Mar;108:151-157. Abstract This review of noncontrolled prescription and over-the-counter drugs that can be and have been abused for non-medical or recreational purposes is rather sketchy and anecdotal (as the authors admit,) but nevertheless contains some useful information. Classes of drugs discussed include: Cold & Cough products: pseudoephedrine, ephedrine, oxymetazoline, dextromethorphan Anticholinergics: diphenhydramine, benztropine, trihexyphenidyl (Artane) Antipsychotics: quetiap...
Source: The Poison Review - March 24, 2015 Category: Toxicology Authors: Leon Tags: Medical cough/cold preparations dextromethorphan medication abuse otc over-the-counter Source Type: news

Schizophrenia Drug Deaths Inconclusive, FDA SaysSchizophrenia Drug Deaths Inconclusive, FDA Says
An animal study suggests that much of the increase in olanzapine bloodstream levels occurred after — not before — the deaths of two patients in 2013. News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 23, 2015 Category: Consumer Health News Tags: Psychiatry News Alert Source Type: news

Zyprexa Relprevv (olanzapine pamoate): Drug Safety Communication - FDA Review of Study Sheds Light on Two Deaths Associated with the Injectable Schizophrenia Drug
FDA is unable to exclude the possibility that the deaths were caused by rapid, but delayed, entry of the drug into the bloodstream following intramuscular injection. (Source: FDA MedWatch)
Source: FDA MedWatch - March 23, 2015 Category: American Health Source Type: news

Excellent review of lipid rescue therapy
3.5 out of 5 stars Intravenous Lipid Emulsion in the Emergency Department: A Systematic Review of Recent Literature. Cao D et al. J Emerg Med 2014 Dec 19 [Epub ahead of print] Abstract This excellent comprehensive review of lipid rescue therapy (LRT) is vitiated only by the unavoidable fact that available clinical evidence  is so inconclusive. As the authors point out, published literature consists mostly of case reports and small case series. The vast majority of these reported cases have good outcomes and reflect positive effects from ILE, but the evidence is marred by multiple confounding variables (such ...
Source: The Poison Review - February 25, 2015 Category: Toxicology Authors: Leon Tags: Medical intralipid lipid emulsion lipid rescue therapy lipid sink Review Source Type: news

Media dementia scare over hay fever and sleep drugs
Conclusion This large US prospective cohort study suggests a link between those taking high levels of anticholinergic medicines for more than three years and developing dementia in adults over 65. The main statistically significant finding was in a group taking the equivalent of any of the following medications daily for more than three years: xybutynin chloride, 5mg chlorpheniramine maleate, 4mg olanzapine, 2.5mg meclizine hydrochloride, 25mg doxepin hydrochloride, 10mg These are not unrealistic doses of medicine, so the results may be applicable to a significant proportion of older adults. The main lim...
Source: NHS News Feed - January 27, 2015 Category: Consumer Health News Tags: Medication Neurology Source Type: news

olanzapine, Zyprexa, Zydis, Zyprexa Relprevv
Title: olanzapine, Zyprexa, Zydis, Zyprexa RelprevvCategory: MedicationsCreated: 7/23/1998 12:00:00 AMLast Editorial Review: 1/12/2015 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - January 12, 2015 Category: Drugs & Pharmacology Source Type: news

Positive Topline Phase 2 Results for Novel Schizophrenia DrugPositive Topline Phase 2 Results for Novel Schizophrenia Drug
A novel oral antipsychotic proves as effective as olanzapine with less weight gain in patients with schizophrenia. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - January 7, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news

An evaluation of the use of olanzapine pamoate depot injection in seriously violent men with schizophrenia in a UK high-security hospital - Baruch N, Das M, Sharda A, Basu A, Bajorek T, Ross CC, Sengupta S, Larkin F, Young S.
BACKGROUND: Oral olanzapine is a well-established treatment for patients suffering from schizophrenia. Advantages of depot olanzapine may include improved compliance. However, it is expensive, causes metabolic side effects, and carries a risk of postinject... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - November 8, 2014 Category: Global & Universal Tags: Occupational Issues Source Type: news

Is Metformin Helpful for Weight Loss When...
It's well known that atypical antipsychotics (AAPs) such as Zyprexa and Seroquel cause weight gain. Can the diabetes drug metformin help? (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - October 25, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

Should You Take Symbyax for Your Bipolar...
Symbyax is a combination of olanzapine, the active ingredient in Zyprexa, and fluoxetine, the active ingredient in Prozac. It is the first medication approved by the FDA the treatment of the depressive phase of bipolar disorder. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - July 12, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

New Antipsychotic Drug Latuda Better for Your Weight
Latuda, a fairly new antipsychotic, has been shown to be effective in treating schizophrenia and has now been approved for use in bipolar depression. The three other atypical antipsychotics - Seroquel, Zyprexa and Symbyax - that are already approved for bipolar depression all have problems with side effects - particularly on weight gain and the related metabolic issues of increased blood glucose and elevated cholesterol and triglycerides. Latuda, by contrast, is considered weight neutral. Read Full PostNew Antipsychotic Drug Latuda Better for Your Weight originally appeared on About.com Bipolar Disorder on Tuesday, March ...
Source: About.com Bipolar Disorder - March 11, 2014 Category: Psychiatry Source Type: news

Striking Changes in Psychiatrists' Antipsychotic PrescribingStriking Changes in Psychiatrists' Antipsychotic Prescribing
Psychiatrists diversify their choice of antipsychotic, back away from olanzapine, a study finds. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 27, 2013 Category: Consumer Health News Tags: Psychiatry News Source Type: news

Zyprexa, Zyprexa Zydis (Olanzapine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 16, 2013 Category: Drugs & Pharmacology Source Type: news

Torrent recalls anti-psychotic tablet from US market
Torrent Pharma Inc, a US subsidiary of Ahmedabad-based Torrent Pharma is recalling anti-psychotic drug Olanzapine 10 mg tablets from the US market. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 8, 2013 Category: Pharmaceuticals Source Type: news

Zyprexa / Olanzapine - Antipsychotic Drug...
Zyprexa - generic olanzapine - is an atypical antipsychotic medication used to treat schizophrenia, bipolar disorder, and also Alzheimers disease. Here is in-depth information about this drug. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - July 10, 2013 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news

FDA investigating two deaths after olanzapine injections
Read the full story on MD Consult: FDA investigating two deaths after olanzapine injections (Source: MD Consult: News: Top Stories)
Source: MD Consult: News: Top Stories - June 21, 2013 Category: Journals (General) Source Type: news

FDA investigates death of patients taking Eli Lilly antipsychotic drug
After the deaths of two patients three to four days after taking Eli Lilly's antipsychotic drug Zyprexa Relprevv, the US Food and Drug Administration has announced it is launching a formal investigation. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - June 18, 2013 Category: Pharmaceuticals Source Type: news