Novel Schizophrenia Drug Continues to Show PromiseNovel Schizophrenia Drug Continues to Show Promise
A novel, potent mu-opioid antagonist with olanzapine is designed to attenuate olanzapine-induced metabolic side effects. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 6, 2015 Category: Consumer Health News Tags: Psychiatry News Source Type: news
Non-controlled and over-the-counter drugs of abuse
2.5 out of 5 stars
Abuse of Medications That Theoretically Are Without Abuse Potential. Reeves RR et al. South Med J 2015 Mar;108:151-157.
Abstract
This review of noncontrolled prescription and over-the-counter drugs that can be and have been abused for non-medical or recreational purposes is rather sketchy and anecdotal (as the authors admit,) but nevertheless contains some useful information.
Classes of drugs discussed include:
Cold & Cough products: pseudoephedrine, ephedrine, oxymetazoline, dextromethorphan
Anticholinergics: diphenhydramine, benztropine, trihexyphenidyl (Artane)
Antipsychotics: quetiapine,...
Source: The Poison Review - March 24, 2015 Category: Toxicology Authors: Leon Tags: Medical cough/cold preparations dextromethorphan medication abuse otc over-the-counter Source Type: news
Schizophrenia Drug Deaths Inconclusive, FDA SaysSchizophrenia Drug Deaths Inconclusive, FDA Says
An animal study suggests that much of the increase in olanzapine bloodstream levels occurred after — not before — the deaths of two patients in 2013. News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 23, 2015 Category: Consumer Health News Tags: Psychiatry News Alert Source Type: news
Zyprexa Relprevv (olanzapine pamoate): Drug Safety Communication - FDA Review of Study Sheds Light on Two Deaths Associated with the Injectable Schizophrenia Drug
FDA is unable to exclude the possibility that the deaths were caused by rapid, but delayed, entry of the drug into the bloodstream following intramuscular injection. (Source: FDA MedWatch)
Source: FDA MedWatch - March 23, 2015 Category: American Health Source Type: news
Excellent review of lipid rescue therapy
3.5 out of 5 stars
Intravenous Lipid Emulsion in the Emergency Department: A Systematic Review of Recent Literature. Cao D et al. J Emerg Med 2014 Dec 19 [Epub ahead of print]
Abstract
This excellent comprehensive review of lipid rescue therapy (LRT) is vitiated only by the unavoidable fact that available clinical evidence is so inconclusive. As the authors point out, published literature consists mostly of case reports and small case series. The vast majority of these reported cases have good outcomes and reflect positive effects from ILE, but the evidence is marred by multiple confounding variables (such as concurren...
Source: The Poison Review - February 25, 2015 Category: Toxicology Authors: Leon Tags: Medical intralipid lipid emulsion lipid rescue therapy lipid sink Review Source Type: news
Media dementia scare over hay fever and sleep drugs
Conclusion
This large US prospective cohort study suggests a link between those taking high levels of anticholinergic medicines for more than three years and developing dementia in adults over 65.
The main statistically significant finding was in a group taking the equivalent of any of the following medications daily for more than three years:
xybutynin chloride, 5mg
chlorpheniramine maleate, 4mg
olanzapine, 2.5mg
meclizine hydrochloride, 25mg
doxepin hydrochloride, 10mg
These are not unrealistic doses of medicine, so the results may be applicable to a significant proportion of older adults.
Th...
Source: NHS News Feed - January 27, 2015 Category: Consumer Health News Tags: Medication Neurology Source Type: news
olanzapine, Zyprexa, Zydis, Zyprexa Relprevv
Title: olanzapine, Zyprexa, Zydis, Zyprexa RelprevvCategory: MedicationsCreated: 7/23/1998 12:00:00 AMLast Editorial Review: 1/12/2015 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - January 12, 2015 Category: Drugs & Pharmacology Source Type: news
Positive Topline Phase 2 Results for Novel Schizophrenia DrugPositive Topline Phase 2 Results for Novel Schizophrenia Drug
A novel oral antipsychotic proves as effective as olanzapine with less weight gain in patients with schizophrenia. Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - January 7, 2015 Category: Psychiatry Tags: Psychiatry News Source Type: news
Antipsychotic Tx Linked to Adiposity Changes in Youths
Greatest increase in fat with olanzapine; significant decrease in insulin sensitivity in pooled analysis (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - November 11, 2014 Category: Psychiatry Tags: Endocrinology, Family Medicine, Pediatrics, Pharmacy, Psychiatry, Journal, Source Type: news
An evaluation of the use of olanzapine pamoate depot injection in seriously violent men with schizophrenia in a UK high-security hospital - Baruch N, Das M, Sharda A, Basu A, Bajorek T, Ross CC, Sengupta S, Larkin F, Young S.
BACKGROUND: Oral olanzapine is a well-established treatment for patients suffering from schizophrenia. Advantages of depot olanzapine may include improved compliance. However, it is expensive, causes metabolic side effects, and carries a risk of postinject... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - November 8, 2014 Category: Global & Universal Tags: Occupational Issues Source Type: news
Is Metformin Helpful for Weight Loss When...
It's well known that atypical antipsychotics (AAPs) such as Zyprexa and Seroquel cause weight gain. Can the diabetes drug metformin help? (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - October 25, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news
Should You Take Symbyax for Your Bipolar...
Symbyax is a combination of olanzapine, the active ingredient in Zyprexa, and fluoxetine, the active ingredient in Prozac. It is the first medication approved by the FDA the treatment of the depressive phase of bipolar disorder. (Source: About.com Bipolar Disorder)
Source: About.com Bipolar Disorder - July 12, 2014 Category: Psychiatry Authors: bipolar.guide at about.com Tags: health Source Type: news
New Antipsychotic Drug Latuda Better for Your Weight
Latuda, a fairly new antipsychotic, has been shown to be effective in treating schizophrenia and has now been approved for use in bipolar depression. The three other atypical antipsychotics - Seroquel, Zyprexa and Symbyax - that are already approved for bipolar depression all have problems with side effects - particularly on weight gain and the related metabolic issues of increased blood glucose and elevated cholesterol and triglycerides.
Latuda, by contrast, is considered weight neutral. Read Full PostNew Antipsychotic Drug Latuda Better for Your Weight originally appeared on About.com Bipolar Disorder on Tuesday, March...
Source: About.com Bipolar Disorder - March 11, 2014 Category: Psychiatry Source Type: news
Striking Changes in Psychiatrists' Antipsychotic PrescribingStriking Changes in Psychiatrists' Antipsychotic Prescribing
Psychiatrists diversify their choice of antipsychotic, back away from olanzapine, a study finds. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 27, 2013 Category: Consumer Health News Tags: Psychiatry News Source Type: news
Zyprexa, Zyprexa Zydis (Olanzapine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 16, 2013 Category: Drugs & Pharmacology Source Type: news
