Comparison of a 22G Crown-Cut Needle with a Conventional 22G Needle with EBUS Guidance in Diagnosis of Sarcoidosis
ConclusionsDespite equivalence in diagnostic accuracy, the crown-cut needle was superior to the conventional needle in detecting granulomas and histiocytes. This indicates greater potential for obtaining higher quality sample material with the crown-cut needle in cases of granulomatous inflammation. (Source: Lung)
Source: Lung - September 1, 2022 Category: Respiratory Medicine Source Type: research
Avanafil as a Novel Therapeutic Agent Against LPS-Induced Acute Lung Injury via Increasing CGMP to Downregulate the TLR4-NF- κB-NLRP3 Inflammasome Signaling Pathway
ConclusionWe suggest that avanafil may prevent the progression of ALI and be effective in its treatment. We hope that this study will be supported by future clinical studies to yield a new indication for avanafil. (Source: Lung)
Source: Lung - August 30, 2022 Category: Respiratory Medicine Source Type: research
Impact of High-Grade Patterns in Early-Stage Lung Adenocarcinoma: A Multicentric Analysis
ConclusionspT1 lung adenocarcinomas with a high-grade component have similar prognosis of pT2a tumors. (Source: Lung)
Source: Lung - August 21, 2022 Category: Respiratory Medicine Source Type: research
The Statistics of Counting Coughs: Easy as 1, 2, 3?
(Source: Lung)
Source: Lung - August 16, 2022 Category: Respiratory Medicine Source Type: research
Hyperresponsiveness to Extracellular Acidification-Mediated Contraction in Isolated Bronchial Smooth Muscles of Murine Experimental Asthma
ConclusionThese findings suggest that extracellular acidification contributes to the airway hyperresponsiveness, a characteristic feature of bronchial asthma. Further studies are required to identify the receptor(s) responsible for sensing extracellular protons in BSM cells. (Source: Lung)
Source: Lung - August 5, 2022 Category: Respiratory Medicine Source Type: research
Improvements in Objective and Subjective Measures of Chronic Cough with Gefapixant: A Pooled Phase 3 Efficacy Analysis of Predefined Subgroups
ConclusionThese data suggest gefapixant 45 mg provides consistent objective and subjective efficacy across subgroups of individuals with RCC or UCC. (Source: Lung)
Source: Lung - July 27, 2022 Category: Respiratory Medicine Source Type: research
Factors Affecting Domiciliary Non-Invasive Ventilation Compliance
In conclusion, younger and comorbid schizophrenic patients have lower D-NIV compliance rates, and our data suggest that persistence with D-NIV over a year may improve overall use. (Source: Lung)
Source: Lung - July 24, 2022 Category: Respiratory Medicine Source Type: research
