Is this the Dawning of AI for Sarcoidosis?
(Source: Lung)
Source: Lung - September 20, 2023 Category: Respiratory Medicine Source Type: research

Current Applications of Artificial Intelligence in Sarcoidosis
ConclusionsMachine learning may be used to help diagnose pulmonary sarcoidosis and prognosticate in cardiac sarcoidosis. Deep learning is most comprehensively studied for diagnosis of pulmonary sarcoidosis and has less frequently been applied to prognostication in cardiac sarcoidosis. Radiomics has primarily been used to differentiate sarcoidosis from malignancy. To date, the use of AI in sarcoidosis is limited by the rarity of this disease, leading to small, suboptimal training sets. Nevertheless, there are applications of AI that have been used to study other systemic diseases, which may be adapted for use in sarcoidosis...
Source: Lung - September 20, 2023 Category: Respiratory Medicine Source Type: research

Is this the Dawning of AI for Sarcoidosis?
(Source: Lung)
Source: Lung - September 20, 2023 Category: Respiratory Medicine Source Type: research

Increased Fungal Infection Mortality Induced by Concurrent Viral Cellular Manipulations
AbstractCertain respiratory fungal pathogen mono-infections can cause high mortality rates. Several viral pathogen mono-infections, including influenza viruses and coronaviruses including SARS-CoV-2, can also cause high mortality rates. Concurrent infections by fungal pathogens and highly manipulative viral pathogens can synergistically interact in the respiratory tract to substantially increase their mortality rates. There are at least five viral manipulations which can assist secondary fungal infections. These viral manipulations include the following: (1) inhibiting transcription factors and cytokine expressions, (2) im...
Source: Lung - September 5, 2023 Category: Respiratory Medicine Source Type: research

Baseline Cohort Profile of the Korean Chronic Cough Registry: A Multicenter, Prospective, Observational Study
ConclusionsChronic cough typically develops in adulthood, lasting for years. Cough severity and quality of life impairment indicate the presence of unmet clinical needs and insufficient cough control in real-world clinical practice. Longitudinal follow-up is warranted to investigate the natural history and treatment outcomes. (Source: Lung)
Source: Lung - September 2, 2023 Category: Respiratory Medicine Source Type: research

Abstracts from the 2023 American Cough Conference
(Source: Lung)
Source: Lung - August 2, 2023 Category: Respiratory Medicine Source Type: research

Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two-Sample Mendelian Randomization Study
ConclusionsThe increase in serum adiponectin was associated causally with a decreased risk of developing IPF. There is no evidence to support a causal association between leptin, resistin or MCP-1 with risk of IPF. Further studies are needed to confirm our findings. (Source: Lung)
Source: Lung - August 2, 2023 Category: Respiratory Medicine Source Type: research

Abstracts from the 2023 American Cough Conference
(Source: Lung)
Source: Lung - August 2, 2023 Category: Respiratory Medicine Source Type: research

Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two-Sample Mendelian Randomization Study
ConclusionsThe increase in serum adiponectin was associated causally with a decreased risk of developing IPF. There is no evidence to support a causal association between leptin, resistin or MCP-1 with risk of IPF. Further studies are needed to confirm our findings. (Source: Lung)
Source: Lung - August 2, 2023 Category: Respiratory Medicine Source Type: research

ETS1 Ameliorates Hyperoxia-Induced Bronchopulmonary Dysplasia in Mice by Activating Nrf2/HO-1 Mediated Ferroptosis
ConclusionETS1 is important in oxidative stress-related ferroptosis in a hyperoxia-induced BPD model, and the effect is partially mediated by the Nrf2/HO-1 axis. (Source: Lung)
Source: Lung - July 25, 2023 Category: Respiratory Medicine Source Type: research

Investigation of Early-Stage Non-Small Cell Lung Cancer Patients with Different T2 Descriptors: Real Word Data From a Large Database
ConclusionT2 tumors with visceral pleural invasion (size: 30 –40 mm) should be assigned to the T2b category, and those with a size interval of 0–30 mm should be assigned to a better prognostic T2a category. (Source: Lung)
Source: Lung - July 24, 2023 Category: Respiratory Medicine Source Type: research