Effects of Pulmonary Rehabilitation Including Inspiratory Muscle Training in Patients with Chronic Obstructive Pulmonary Disease after Stratification by the Degree of Static Hyperinflation
ConclusionsIMT as part of a PR program in patients with COPD with different baseline degrees improved MIP irrespective of the degree of static lung hyperinflation. Improvement in functional exercise capacity was significantly higher in the group with the lowest degree of static hyperinflation compared with the patients with the highest degree of static hyperinflation. (Source: Lung)
Source: Lung - July 19, 2022 Category: Respiratory Medicine Source Type: research
Acute Effect of Bronchodilator on Intrathoracic Airway Wall Compliance in COPD Patients
ConclusionIn COPD patients, AWC is reduced compared to controls, but after bronchodilator, the intrathoracic airways become more compliant. The consequent increased collapsibility under high positive pleural pressure could limit the airway caliber improvement seen after bronchodilator, as assessed by the FEV1 changes during the forced expiratory maneuver, underestimating the effective bronchodilation achieved in these patients. (Source: Lung)
Source: Lung - July 18, 2022 Category: Respiratory Medicine Source Type: research
Plasma Lipid Profiling Identifies Phosphatidylcholine 34:3 and Triglyceride 52:3 as Potential Markers Associated with Disease Severity and Oxidative Status in Chronic Obstructive Pulmonary Disease
ConclusionPC (34:3) and TG (52:3) could be potential lipid signatures of COPD that correlate with altered pulmonary function and oxidative status. (Source: Lung)
Source: Lung - July 11, 2022 Category: Respiratory Medicine Source Type: research
Cough Presentation and Cough-Related Healthcare Utilization in Tertiary Care: Analysis of Routinely Collected Academic Institutional Database
ConclusionsCough is a common chief complaint at allergy and asthma clinics, but the clinical presentation may be heterogeneous. Further studies are needed to understand long-term outcomes and reduce the disease burden. (Source: Lung)
Source: Lung - July 9, 2022 Category: Respiratory Medicine Source Type: research
Decreasing Hospital Readmissions Utilizing an Evidence-Based COPD Care Bundle
ConclusionBundled care is an effective and inexpensive method for institutions to provide consistent and quality care. The findings of this study demonstrate that the implementation of a COPD care bundle is an effective strategy to decrease hospital readmissions. (Source: Lung)
Source: Lung - July 7, 2022 Category: Respiratory Medicine Source Type: research
Cytomegalovirus Infection Is Associated with Development of Chronic Lung Allograft Dysfunction
AbstractBackgroundCytomegalovirus (CMV) is the major and most common opportunistic infection complicating lung transplant (LTX). The aim of this study was to analyse the epidemiological aspects of CMV infection in lung transplant patients subject to a pre-emptive anti-CMV approach and to study the impact of this infection on lung transplant outcome, in terms of onset of chronic lung allograft dysfunction (CLAD).MethodsThis single-centre retrospective study enrolled 87 LTX patients (median age 55.81 years; 41 females, 23 single LTX, 64 bilateral LTX). All patients were managed with a pre-emptive anti-CMV approach. The inc...
Source: Lung - July 6, 2022 Category: Respiratory Medicine Source Type: research
Stage I and II Small-Cell Lung Cancer —New Challenge for Surgery
ConclusionOur meta-analysis shows a significant survival benefit after surgery not only in the recommended stage I but also in stage II SCLC. Our data suggests that both stages should be considered for surgery of early SCLC. (Source: Lung)
Source: Lung - June 30, 2022 Category: Respiratory Medicine Source Type: research
Quantitative Computed Tomography: What Clinical Questions Can it Answer in Chronic Lung Disease?
AbstractQuantitative computed tomography (QCT) has recently gained an important role in the functional assessment of chronic lung disease. Its capacity in diagnostic, staging, and prognostic evaluation in this setting is similar to that of traditional pulmonary function testing. Furthermore, it can demonstrate lung injury before the alteration of pulmonary function test parameters, and it enables the classification of disease phenotypes, contributing to the customization of therapy and performance of comparative studies without the intra- and inter-observer variation that occurs with qualitative analysis. In this review, w...
Source: Lung - June 25, 2022 Category: Respiratory Medicine Source Type: research
