Prognostic Value of Geriatric Nutritional Risk Index for Patients with Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis
ConclusionData indicate that GNRI has good prognostic ability in patients with NSCLC. Individuals with low GNRI are at an increased risk of poor OS and DFS. GNRI could be incorporated as a simple, easy-to-use tool for the initial stratification of patients thereby allowing focused treatment plans. (Source: Lung)
Source: Lung - September 16, 2022 Category: Respiratory Medicine Source Type: research

Activation of Autophagy Induces Monocrotaline-Induced Pulmonary Arterial Hypertension by FOXM1-Mediated FAK Phosphorylation
ConclusionFOXM1 promotes the development of PAH by inducing FAK phosphorylation and subsequent activation of autophagy in MCT-treated rats. (Source: Lung)
Source: Lung - September 15, 2022 Category: Respiratory Medicine Source Type: research

Serum Creatinine/Cystatin C Ratio as a Predictor of In-hospital Mortality in Patients Hospitalized with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
ConclusionsCCR was significantly lower, and is a potential prognostic indicator, in patients with AECOPD who died during hospitalization. (Source: Lung)
Source: Lung - September 15, 2022 Category: Respiratory Medicine Source Type: research

Activation of Autophagy Induces Monocrotaline-Induced Pulmonary Arterial Hypertension by FOXM1-Mediated FAK Phosphorylation
ConclusionFOXM1 promotes the development of PAH by inducing FAK phosphorylation and subsequent activation of autophagy in MCT-treated rats. (Source: Lung)
Source: Lung - September 15, 2022 Category: Respiratory Medicine Source Type: research

Serum Creatinine/Cystatin C Ratio as a Predictor of In-hospital Mortality in Patients Hospitalized with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
ConclusionsCCR was significantly lower, and is a potential prognostic indicator, in patients with AECOPD who died during hospitalization. (Source: Lung)
Source: Lung - September 15, 2022 Category: Respiratory Medicine Source Type: research

EUS-B-FNA Enhances the Diagnostic Yield of EBUS Bronchoscope for Intrathoracic Lesions
ConclusionPulmonologists are able to enhance diagnostic yields by acquiring the EUS-B-FNA technique. (Source: Lung)
Source: Lung - September 8, 2022 Category: Respiratory Medicine Source Type: research

Trajectories of Severe Exacerbations of Chronic Obstructive Pulmonary Disease and Their Relationship with Mortality Risk
ConclusionDifferent possible trajectories of severe AECOPD before and after a first specialized consultation are associated with different mortality risks. An inconsistent pattern of exacerbations has a mortality risk between Ex and NEx, with no clear differences between CONV-Ex and CONV-NEx. (Source: Lung)
Source: Lung - September 5, 2022 Category: Respiratory Medicine Source Type: research

Comparison of a 22G Crown-Cut Needle with a Conventional 22G Needle with EBUS Guidance in Diagnosis of Sarcoidosis
ConclusionsDespite equivalence in diagnostic accuracy, the crown-cut needle was superior to the conventional needle in detecting granulomas and histiocytes. This indicates greater potential for obtaining higher quality sample material with the crown-cut needle in cases of granulomatous inflammation. (Source: Lung)
Source: Lung - September 1, 2022 Category: Respiratory Medicine Source Type: research

Avanafil as a Novel Therapeutic Agent Against LPS-Induced Acute Lung Injury via Increasing CGMP to Downregulate the TLR4-NF- κB-NLRP3 Inflammasome Signaling Pathway
ConclusionWe suggest that avanafil may prevent the progression of ALI and be effective in its treatment. We hope that this study will be supported by future clinical studies to yield a new indication for avanafil. (Source: Lung)
Source: Lung - August 30, 2022 Category: Respiratory Medicine Source Type: research