Identification of Idiopathic Pulmonary Fibrosis and Prediction of Disease Severity via Machine Learning Analysis of Comprehensive Metabolic Panel and Complete Blood Count Data
ConclusionAnalysis of CMP and CBC data via proposed ML methodology offers the potential to distinguish IPF from CTD-ILD and predict severity on associated PFT with accuracy that meets or exceeds current clinical practice. (Source: Lung)
Source: Lung - February 20, 2024 Category: Respiratory Medicine Source Type: research
Missing Nuts and Bolts: Translating Pulmonary Fibrosis from Preclinical Murine Models to Human Clinical Trials
(Source: Lung)
Source: Lung - February 7, 2024 Category: Respiratory Medicine Source Type: research
Cardiovascular Events with the Use of Long-Acting Muscarinic Receptor Antagonists: An Analysis of the FAERS Database 2020 –2023
ConclusionOur study suggests that inhaled LAMAs are not free from cardiac AE risks. This risk may be more evident when the newer LAMAs are used, but it is generally significantly reduced when COPD patients are treated with dual bronchodilators or triple therapy. However, these results do not prove that LAMAs cause CV AEs, as FAERS data alone are not indicative of a drug ’s safety profile. Given the frequency with which COPD and cardiovascular disease co-exist, a large study in the general population could shed light on this very important issue. (Source: Lung)
Source: Lung - February 6, 2024 Category: Respiratory Medicine Source Type: research
LUNG Year in Review: 2023
(Source: Lung)
Source: Lung - February 2, 2024 Category: Respiratory Medicine Source Type: research
Efficacy and Safety of Re-administration of Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor (EGFR-TKI) After EGFR-TKI-Induced Interstitial Lung Disease (CS-Lung-005)
ConclusionThis study showed that EGFR-TKI re-administration is a feasible and effective treatment for patients who recovered from EGFR-TKI-induced ILD. Our results indicate that re-administration of EGFR-TKI is an important option for long-term prognosis after recovery from EGFR-TKI-induced ILD. (Source: Lung)
Source: Lung - January 24, 2024 Category: Respiratory Medicine Source Type: research
Predictors of Early and Late Lung Function Improvement in Severe Eosinophilic Asthma on Type2-Biologics in the PRISM Study
ConclusionFactors predicting the efficacy of biological agents that improve lung function in SEA vary according to the stage of response. (Source: Lung)
Source: Lung - January 22, 2024 Category: Respiratory Medicine Source Type: research
Elevated Eosinophil Counts in Acute Exacerbations of Bronchiectasis: Unveiling a Distinct Clinical Phenotype
ConclusionsThese findings suggest that EB presents a distinct pattern of bronchiectasis features, confirming the notion that it is a specific phenotype. (Source: Lung)
Source: Lung - January 16, 2024 Category: Respiratory Medicine Source Type: research
