Fasciculo-Ventricular Pathways As A Mechanism Of Bundle Branch Block Correction: An Intriguing But Not Unfalsifiable Hypothesis
His bundle pacing (HBP) can correct the ECG appearance of left bundle branch block (LBBB) at least as effectively as biventricular pacing for cardiac resynchronization therapy (CRT).1 Although more distal left-sided conduction system pacing, left bundle branch pacing (LBBP), has risen to prominence in recent years, HBP-CRT ’s remarkable ability to apparently normalize conduction system function in both ventricles has entrenched it as an important modality, with guideline endorsement.2 Importantly, this meteoric rise has occurred despite some uncertainty regarding the mechanism by which HBP is able to normalize the E CG a...
Source: Heart Rhythm - January 31, 2024 Category: Cardiology Authors: Ahran D. Arnold, Pugazhendhi Vijayaraman Source Type: research
Duration of Atrial Fibrillation Persistence: Implications for Recurrence Risk after Catheter Ablation and Efficacy of Additional Substrate Ablation
The optimal duration of atrial fibrillation (AF) persistence for predicting poor outcomes post-catheter ablation of longstanding-persistent AF (LsAF) and the best ablation strategy for these patients remain unclear. (Source: Heart Rhythm)
Source: Heart Rhythm - January 31, 2024 Category: Cardiology Authors: Yasuharu Matsunaga-Lee, Koichi Inoue, Nobuaki Tanaka, Masaharu Masuda, Tetsuya Watanabe, Nobuhiko Makino, Yasuyuki Egami, Takafumi Oka, Hitoshi Minamiguchi, Miwa Miyoshi, Masato Okada, Takashi Kanda, Yasuhiro Matsuda, Masato Kawasaki, Shodai Kawanami, Koh Source Type: research
The Right Atrium Affects in silico Arrhythmia Vulnerability in Both Atria
The role of the right atrium (RA) in atrial fibrillation (AF) has long been overlooked. Multiple studies have examined clinical conditions associated with AF, such as atrial enlargement, fibrosis extent, electrical remodeling, and wall thickening, but have been mainly concentrated on the left atrium (LA). AF research predominantly focuses on the LA due to two key paradigms: Firstly, the well-established view that AF onset is primarly triggered by activity originating in the pulmonary veins (PVs) of the LA [1]. (Source: Heart Rhythm)
Source: Heart Rhythm - January 30, 2024 Category: Cardiology Authors: Patricia Mart ínez Díaz, Jorge Sánchez, Nikola Fitzen, Ursula Ravens, Olaf Dössel, Axel Loewe Source Type: research
CAST: A study that rocked the cardiology world and became the poster child for evidence-based medicine
The main result of the CAST (Cardiac Arrhythmia Suppression Trial), shown in Figure 1,1 was completely unexpected: The suppression of ventricular ectopy with antiarrhythmic drugs (AADs) was associated with an increased incidence of lethal ventricular arrhythmias in patients with post–myocardial infarction (post-MI) at high risk of sudden cardiac death (SCD). (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Debra Echt Tags: Iconic Figure Source Type: research
Preventing ventricular arrhythmia after transcatheter pulmonary valve placement for repaired tetralogy of Fallot
Tetralogy of Fallot (TOF) is the most prevalent form of cyanotic congenital heart disease and has become the poster child for the evolution and success of neonatal cardiac surgery. Over the past few decades, dramatic improvements in survival have shifted focus away from early surgical repair toward preservation of cardiac mechanical and electrical stability, particularly as they relate to abnormalities of the right ventricular outflow tract (RVOT). With the advent of self-expanding transcatheter valves that can be safely deployed into the native RVOT, it is now possible to avoid repeat cardiac operations to address progres...
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Jeremy P. Moore Tags: Top Stories Source Type: research
Top stories on congenital long QT syndrome
This is a one-eyed, understandably skewed selection of recent articles on long QT syndrome (LQTS) all sharing very practical clinical implications. (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Peter J. Schwartz, Federica Dagradi, Fulvio L.F. Giovenzana Tags: Top Stories Source Type: research
Top Stories: Mitochondrial origin of inherited cardiac arrhythmias
Mitochondria control cardiac function by regulating adenosine triphosphate synthesis, reactive oxygen species (ROS) generation, intracellular calcium (Ca2+), and the cellular redox state. Yet, their role in the pathophysiology of arrhythmias remains massively underappreciated. In this Top Stories article, we shed light on this issue by focusing on recent advances in our understanding of mechanisms by which mitochondria act as central mediators of inherited arrhythmic disorders. (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Fadi G. Akar, Christoph Maack Tags: Top Stories Source Type: research
Heart Rhythm Society Quality Improvement Committee update
Heart Rhythm Society (HRS) committees have been created to advance our strategic goals, which evolve over time in response to scientific advances, clinical needs, external forces, and internal capabilities. The Quality Improvement (QI) Committee is a relatively new committee, formed in 2017. It was created to position HRS in a leadership role as value-based care models evolve and become more commonplace, with an emphasis increasingly placed on maximizing clinical outcomes while improving efficiency by decreasing unnecessary variation and minimizing waste. (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Thomas F. Deering, John N. Catanzaro, Roopinder K. Sandhu, Matthew Singleton, Srikant Das, Marc W. Deyell, Siva K. Mulpuru, Christina L. Magnelli-Reyes, Bruce A. Koplan, Gaston R. Vergara, Christopher Austin, Fabrizio R. Assis, Kun Xiang, Michelle Moore, Tags: HRS Committee/Council Viewpoints Source Type: research
Editorial Board
(Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Source Type: research
Table of Contents
(Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Source Type: research
Predictors of nonpulmonary vein triggers for atrial fibrillation: A clinical risk score
Targeting nonpulmonary vein triggers (NPVTs) after pulmonary vein isolation may reduce atrial fibrillation (AF) recurrence. Isoproterenol infusion and cardioversion of spontaneous or induced AF can provoke NPVTs but typically require vasopressor support and increased procedural time. (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Munveer Thind, Alireza Oraii, Corentin Chaumont, Mart ín R. Arceluz, Masahiro Sekigawa, Haran Yogasundaram, Alan Sugrue, Maiwand Mirwais, Ahmed B. AlSalem, Erica S. Zado, Gustavo S. Guandalini, Timothy M. Markman, Rajat Deo, Robert D. Schaller, Sanjay Di Source Type: research
Disputation on the Power and Efficacy of Phenotypical Classification in Arrhythmogenic Cardiomyopathy: Time for a Reformation?!
Representing the spark that lit the Protestant Reformation, on the 31st of October Anno Domini 1517 Reverend Martin Luther sent the manuscript entitled “Disputation on the Power and Efficacy of Indulgences” to the Archbishop of Mainz for academic disputation or, as it would be called today, external peer review. This document challenged well-established religious beliefs of the time, leading to massive changes across a society ripe for transfor mation yet deeply entrenched into outdated believes. (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Alessio Gasperetti, Babken Asatryan Source Type: research
Minimally Invasive Epicardial Surgical Left Atrial Appendage Exclusion for Atrial Fibrillation Patients at High Risk of Stroke and of Bleeding
Atrial fibrillation (AF) patients at high risk for stroke and also at high risk for bleeding may be unsuitable for either oral anticoagulation or endocardial left atrial appendage (LAA) occlusion. However, minimally invasive, epicardial LAA exclusion (LAAE) may be an option. (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: David Z. Rose, Paul DiGiorgi, Basel Ramlawi, Zulkarnain Pulungan, Christie Teigland, Hugh Calkins Source Type: research
Predictors of Non-Pulmonary Vein Triggers for Atrial Fibrillation: A Clinical Risk Score
Targeting non-pulmonary vein triggers (NPVTs) after pulmonary vein isolation may reduce atrial fibrillation (AF) recurrence. Isoproterenol infusion and cardioversion of spontaneous or induced AF can provoke NPVTs but typically require vasopressor support and increased procedure time. (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Munveer Thind, Alireza Oraii, Corentin Chaumont, Mart ín R. Arceluz, Masahiro Sekigawa, Haran Yogasundaram, Alan Sugrue, Maiwand Mirwais, Ahmed B. AlSalem, Erica S. Zado, Gustavo S. Guandalini, Timothy M. Markman, Rajat Deo, Robert D. Schaller, Sanjay Di Source Type: research
Pulsed Field Ablation of the Right Superior Pulmonary Vein Prevents Vagal Responses Via Anterior Right Ganglionated Plexus Modulation
Pulsed field ablation (PFA) is selective for the myocardium. However, vagal responses and reversible effects on ganglionated plexi (GP) are observed during pulmonary vein isolation (PVI). Anterior-right GP ablation has been proven to effectively prevent vagal responses during radiofrequency-based PVI. (Source: Heart Rhythm)
Source: Heart Rhythm - January 28, 2024 Category: Cardiology Authors: Alvise Del Monte, Domenico Giovanni Della Rocca, Luigi Pannone, Giampaolo Vetta, Mar ía Cespón Fernández, Lorenzo Marcon, Ioannis Doundoulakis, Sahar Mouram, Charles Audiat, Sarah Zeriouh, Cinzia Monaco, Maysam Al Housari, Andrés Betancur, Roberto Men Source Type: research
