Catheter ablation of parahisian premature ventricular complexes in patients with and without cardiac scar
Ablation of premature ventricular complexes (PVCs) originating from the parahisian area is challenging. Late gadolinium enhanced cardiac magnetic resonance (LGE-CMR) scar may influence procedural outcomes; the impact of cardiac scar on parahisian PVCs has not been described. (Source: Heart Rhythm)
Source: Heart Rhythm - April 2, 2024 Category: Cardiology Authors: Jamie Simpson, Mohamed Al-Sadawi, Amrish Deshmukh, Jackson J. Liang, Rakesh Latchamsetty, Thomas Crawford, Krit Jongnarangsin, Hakan Oral, Frank Bogun, Michael Ghannam Source Type: research

Accurate Detection of Lead Malfunction From ECG-derived Bipolar Pacing Stimulus Amplitude
One common mode of lead failure is insulation breach which may result in myopotential noise and device malfunction. “Pseudo-unipolarization” of bipolar pacing stimuli, as observed from a routine 12-lead ECG due to stimulus current leak has been observed with insulation breaches. (Source: Heart Rhythm)
Source: Heart Rhythm - April 2, 2024 Category: Cardiology Authors: Michael S. Lloyd, Mary Pelling, Rand Ibrahim, Mikhael F. El-Chami, Shahriar Iravanian Source Type: research

Acute effects of Dantrolene on the mechanical performance of myopathic human hearts
Despite significant progress in pharmacotherapy, ventricular arrhythmia (VA) remains a challenge in heart failure (HF). Use of most conventional anti-arrhythmic drugs is limited by proarrhythmia and/or negative inotropic effects. (Source: Heart Rhythm)
Source: Heart Rhythm - April 2, 2024 Category: Cardiology Authors: Praloy Chakraborty, Mahmoud M. Bokhari, St éphane Massé, Mohammed A. Azam, Patrick F.H. Lai, Timothy Liang, Daoyuan Si, Abhishek Bhaskaran, Sheila Riazi, Filio Billia, Kumaraswamy Nanthakumar Source Type: research

Association of Chronic Kidney Disease and End-Stage Renal Disease with Procedural Complications and Inpatient Outcomes of Leadless Pacemaker Implantations Across the United States
Leadless pacemakers have emerged as a promising alternative to transvenous pacemakers in patients with kidney disease. However, studies investigating leadless pacemaker outcomes and complications based on kidney dysfunction are limited. (Source: Heart Rhythm)
Source: Heart Rhythm - April 2, 2024 Category: Cardiology Authors: Muhammad Zia Khan, Amanda Nguyen, Muhammad Usman Khan, Yasar Sattar, Waleed Alruwaili, Karthik Gonuguntla, Hafiz Muhammad Sohaib Hayat, Melody Mendez, Sameh Nassar, Zain Ul Abideen Asad, Siddharth Agarwal, Sameer Raina, Sudarshan Balla, Bao Nguyen, Dali F Source Type: research

Susceptibility of Atrial Fibrillation in Genetic Architecture and Heritability: A Genome-Wide Association Study in Taiwan
Atrial fibrillation (AF) is a common arrhythmia affecting ∼34 million people worldwide1. Epidemiological studies emphasize the heritable nature of AF2. Hence, several recent studies evaluated the genetic susceptibility of AF using conventional genetic mapping approaches and genome-wide association studies (GWASs). Many common single-nucleotide polymorphi sms (SNPs) have been identified to be associated with AF3,4. However, the genetic vulnerability to AF in the Taiwanese population remains unclear. (Source: Heart Rhythm)
Source: Heart Rhythm - April 2, 2024 Category: Cardiology Authors: Cheng-I Wu, I-Chieh Chen, Yun-Yu Chen, Yi-Ming Chen, Yenn-Jiang Lin, Yu-Chen Hsieh, Shih-Ann Chen Source Type: research

To the Editor — Risk of atrial arrhythmias in arrhythmogenic right ventricular cardiomyopathy patients undergoing ventricular tachycardia ablation
The objective of this study was to determine the type, prevalence, outcome, and risk correlates of atrial arrhythmias in arrhythmogenic right ventricular cardiomyopathy in patients undergoing ventricular tachycardia ablation. The risk score for typical atrial flutter was determined from univariate logistic regression analysis. They then found that the risk score for typical flutter included age>40 years, ≥moderate right ventricular dysfunction, ≥moderate tricuspid regurgitation, ≥moderate right atrial dilation, and right ventricular volume>250 mL, with score>4 identifying 50% prevalence of typical flutter. (Source: Heart Rhythm)
Source: Heart Rhythm - April 1, 2024 Category: Cardiology Authors: Yun Cheng, Qinggang Zhang Source Type: research

Reply to the Editor — Heart transplant, CIED implant, and mortality
We reported longer survival in orthotopic heart transplant patients receiving cardiac implantable electronic devices (CIEDs), noting an early separation of survival curves that “suggest other confounding factors at play.” Dr Wimmer and colleagues note this reflects inherent lead time bias due to time between transplantation and device placement. (Source: Heart Rhythm)
Source: Heart Rhythm - April 1, 2024 Category: Cardiology Authors: Zain Gowani, Michael R. Gold Source Type: research

Regarding the risk of atrial arrhythmias in arrhythmogenic right ventricular cardiomyopathy patients undergoing ventricular tachycardia ablation
The objective of this study was to determine the type, prevalence, outcome, and risk correlates of atrial arrhythmias (AAs) in arrhythmogenic right ventricular cardiomyopathy (ARVC) in patients undergoing ventricular tachycardia (VT) ablation. The risk score for typi cal atrial flutter was determined from univariate logistic regression analysis, then they found that the risk score for typical flutter included age>40 years, ≥moderate right ventricular dysfunction, ≥moderate tricuspid regurgitation, ≥moderate right atrial dilation, and right ventricular volume>250 cc, with score>4 identifying 50% prevalence of typical ...
Source: Heart Rhythm - April 1, 2024 Category: Cardiology Authors: Yun Cheng, Qinggang Zhang Source Type: research

Modernizing cardiovascular medicine board certification: Leveraging innovation and strengthening continuous competency and professional growth
Achieving and maintaining clinical competence in the practice of cardiovascular medicine is fundamental to providing appropriate, patient-centric, high-value health care and is part of the ethical and professional duties of all physicians in their responsibility to patients and the public. (Source: Heart Rhythm)
Source: Heart Rhythm - April 1, 2024 Category: Cardiology Authors: Jodie L. Hurwitz, B. Hadley Wilson, Joseph C. Wu, James C. Fang, George D. Dangas Tags: Editorial Source Type: research

Author ’s Reply to Heart Transplant, CIED Implant and Mortality
We reported longer survival in orthotopic heart transplant patients receiving CIEDs, noting an early separation of survival curves which “suggest other confounding factors at play”. (Source: Heart Rhythm)
Source: Heart Rhythm - April 1, 2024 Category: Cardiology Authors: Zain Gowani, Michael R. Gold Source Type: research

To the Editor — Heart transplant, CIED implant, and mortality
We read with interest the article by Gowani and colleagues.1 Our interest was due in part to our prior work examining the stability of indices of pacemaker function and need for continued pacing of orthotopic heart transplant (OHT) patients, which included a time period during which the biatrial anastomosis technique was still being performed at our institution.2 We were pleased to see a contemporary study on this topic, restricted to patients undergoing cardiac implantable electronic device (CIED) implantation after heart transplantation using the bicaval anastomosis technique. (Source: Heart Rhythm)
Source: Heart Rhythm - March 28, 2024 Category: Cardiology Authors: Alan P. Wimmer, Kevin F. Kennedy, Bethany Austin, Anthony Magalski Source Type: research

Heart Transplant, CIED Implant, and Mortality
We read with interest the article by Gowani et al.1 Our interest was due in part to our prior work examining the stability of indices of pacemaker function and need for continued pacing among orthotopic heart transplant (OHT) patients, which included a time period during which the bi-atrial anastomosis technique was still being performed at our institution.2 We were pleased to see a contemporary study on this topic, restricted to patients undergoing cardiac implantable electronic device (CIED) implant post-heart transplant using the bi-caval anastomosis technique. (Source: Heart Rhythm)
Source: Heart Rhythm - March 28, 2024 Category: Cardiology Authors: Alan P. Wimmer, Kevin F. Kennedy, Bethany Austin, Anthony Magalski Source Type: research

Upper common pathway analysis using late atrial premature depolarization in atrioventricular nodal reentry tachycardia
Anatomic and electrophysiologic findings suggest that the actual circuit of atrioventricular nodal reentrant tachycardia (AVNRT) involves the perinodal atrium. However, occasional instances in which the atrium is dissociated from the AVNRT have led to the concept of an upper common pathway (UCP). (Source: Heart Rhythm)
Source: Heart Rhythm - March 27, 2024 Category: Cardiology Authors: Soyoon Park, Jeong-Wook Park, Soohyun Kim, Hwajung Kim, Sung-Hwan Kim, Yong-Seog Oh, Young Choi Source Type: research

To the Editor — Ganglionated plexus modulation inducing vagal response during pulsed field ablation for atrial fibrillation: A blessing in disguise
We read with great interest the article by Del Monte and colleagues1 and the associated editorial.2 The authors should be congratulated on their study, concluding that initiating pulsed field ablation (PFA) from the right superior pulmonary vein (PV) could potentially prevent vagal pauses caused by PFA of the left PV antrum, thereby eliminating the necessity for pacing support. However, no predefined cutoff for temporary backup pacing was employed in the study, and therefore it is difficult to establish the bradycardia severity. (Source: Heart Rhythm)
Source: Heart Rhythm - March 27, 2024 Category: Cardiology Authors: Marco Schiavone, Claudio Tondo Tags: Letter to the Editor Source Type: research

Ultrahigh-density mapping for evaluation of antral scar extension after ablation with radiofrequency balloon catheter in atrial fibrillation patients
For pulmonary vein isolation (PVI) to be achieved fast and effectively, various “single-shot” devices aiming to create wide antral circumferential lesions have been developed. In this multicenter study, we assessed the extension of the antral scar in patients undergoing their first PVI by means of a radiofrequency (RF) balloon (HelioStar; Biosense Webster, Irvine, CA). The ultrahigh-density voltage maps, before and after ablation, were acquired in sinus rhythm with use of an octa-spline mapping catheter (Octaray; Biosense Webster). (Source: Heart Rhythm)
Source: Heart Rhythm - March 27, 2024 Category: Cardiology Authors: Teresa Strisciuglio, Sara Poggi, Assunta Iuliano, Giorgio Spiniello, Alexandre Almorad, Gian Battista Chierchia, Carlo de Asmundis, Federica Torri, Massimiliano Manfrin, Livio Bertagnolli, Claudio Pandozi, Maurizio Russo, Marco Galeazzi, Giuseppe Stabile Tags: Research Letter Source Type: research