An unruly case of functional two-to-one atrioventricular block
A newborn male was delivered via cesarean section at term due to acute fetal distress and fetal bradycardia, necessitating emergency pacemaker implantation. Physical examination revealed dysmorphic facial features and syndactyly in both upper and lower limbs. An electrocardiogram (ECG) showed a two-to-one atrioventricular (AV) block and a prolonged QT interval, along with biphasic T-waves in V3 (Figure 1A). During hospitalization, the infant experienced multiple seizures and episodes of hypoglycemia. (Source: Heart Rhythm)
Source: Heart Rhythm - March 8, 2024 Category: Cardiology Authors: Muhammed Ali EKSI, Yasemin OZDEMIR SAHAN, Serhat KOCA, Ozcan OZEKE Source Type: research

Effect of reference electrode on intracardiac electrograms: Close indifferent electrode vs Wilson central terminal
Unipolar electrograms (uni-EGMs) are an essential part of intracardiac mapping. Although Wilson central terminal (WCT) is conventionally used as a reference for signals, avoidance of contamination by far-field and nonphysiologic signals is challenging. (Source: Heart Rhythm)
Source: Heart Rhythm - March 7, 2024 Category: Cardiology Authors: Tasuku Yamamoto, Masateru Takigawa, Takatoshi Shigeta, Claire A. Martin, Junji Yamaguchi, Miki Amemiya, Takashi Ikenouchi, Miho Negishi, Iwanari Kawamura, Kentaro Goto, Takuro Nishimura, Tomomasa Takamiya, Susumu Tao, Shinsuke Miyazaki, Masahiko Goya, Tet Source Type: research

Effect of Reference Electrode on Intracardiac Electrograms: Close Indifferent Electrode vs. Wilson Central Terminal
Unipolar electrograms (Uni-EGM) are an essential part of intracardiac mapping. Although Wilson Central Terminal (WCT) is conventionally used as a reference for signals, avoiding contamination by far-field and non-physiological signals is challenging. (Source: Heart Rhythm)
Source: Heart Rhythm - March 7, 2024 Category: Cardiology Authors: Tasuku Yamamoto, Masateru Takigawa, Takatoshi Shigeta, Claire A. Martin, Junji Yamaguchi, Miki Amemiya, Takashi Ikenouchi, Miho Negishi, Iwanari Kawamura, Kentaro Goto, Takuro Nishimura, Tomomasa Takamiya, Susumu Tao, Shinsuke Miyazaki, Masahiko Goya, Tet Source Type: research

Pulsed field ablation prevents left atrial restrictive physiology after posterior wall isolation in patients with persistent atrial fibrillation
Extensive ablation, including posterior wall isolation (PWI) is advocated for radiofrequency ablation (RFA) of persistent atrial fibrillation (peAF) to decrease the high recurrence-rates reported when only pulmonary vein isolation (PVI) is performed.1 However, extensive RFA of the posterior wall may cause fibrosis and “stiff-left-atrium” syndrome.2 3 Magnetic resonance imaging after PVI demonstrates that edema and delayed enhancement are permanent after RFA, but short-lasting after pulsed field ablation (PFA). (Source: Heart Rhythm)
Source: Heart Rhythm - March 7, 2024 Category: Cardiology Authors: Ariel Banai, Ehud Chorin, Arie Lorin Schwartz, Yuval Levi, Hend Sliman, Omri Feder, Dana Viskin, Sami Viskin, Shmuel Banai, Raphael Rosso Source Type: research

Arrhythmia detection using an implantable loop recorder after a negative electrophysiology study in Brugada syndrome: observations from a multicenter international registry
Risk stratification in Brugada syndrome (BrS) remains controversial. In this respect, the role of electrophysiology study (EPS) has been subject of debate. In some centers, it is common practice to use an implantable loop recorder (ILR) after a negative EPS to help risk stratification. However, the diagnostic value of this approach has never been specifically addressed. (Source: Heart Rhythm)
Source: Heart Rhythm - March 6, 2024 Category: Cardiology Authors: Eusebio Garc ía-Izquierdo, Chiara Scrocco, Julián Palacios-Rubio, Amira Assaf, Tomás Ripoll-Vera, Iván Hernandez-Betancor, Pablo Ramos-Ruiz, Antonio Melero-Pita, Melodie Segura-Domínguez, Diego Jiménez-Sánchez, Victor Castro-Urda, Jorge Toquero-Ram Source Type: research

Collateral coronary flow in the interventricular septum detected on intracardiac echocardiographic imaging
A 72-year-old man with severe coronary artery disease and coronary artery bypass grafting complicated by ischemic cardiomyopathy and ventricular tachycardia (VT) was referred for redo VT ablation. Coronary angiography (CA) before the ablation procedure showed a patent left internal mammary artery to the left anterior descending artery graft and occluded venous grafts to the obtuse marginal branch and right coronary artery (RCA) with collateral branches supplying the RCA and circumflex artery. (Source: Heart Rhythm)
Source: Heart Rhythm - March 5, 2024 Category: Cardiology Authors: Fatima M. Ezzeddine, William R. Miranda, Jeremy D. Collins, Ammar M. Killu Tags: Image Source Type: research

Collateral Coronary Flow in the Interventricular Septum Detected on Intracardiac Echocardiography Imaging
A 72-year-old man with severe coronary artery disease (CAD) and coronary artery bypass grafting complicated by ischemic cardiomyopathy and ventricular tachycardia (VT) was referred for redo VT ablation. Coronary angiography (CA) prior to the ablation procedure showed a patent left internal mammary artery (LIMA) to the left anterior descending (LAD) artery graft and occluded venous grafts to the obtuse marginal branch and right coronary artery (RCA) with collateral branches supplying the RCA and circumflex artery. (Source: Heart Rhythm)
Source: Heart Rhythm - March 5, 2024 Category: Cardiology Authors: Fatima M. Ezzeddine, William R. Miranda, Jeremy D. Collins, Ammar M. Killu Source Type: research

Characteristics of Contemporary Atrial Fibrillation Clinical Trials and Their Association With Industry Sponsorship
Industry sponsorship is an important source of funding for atrial fibrillation (AF) clinical trials, the implications of which have not been analyzed. (Source: Heart Rhythm)
Source: Heart Rhythm - March 5, 2024 Category: Cardiology Authors: Roy H. Lan, Ishan Paranjpe, Mohammad Saeed, Marco V. Perez Source Type: research

Evaluation of the in  vivo chemical reactivity of a novel copolymer insulation on cardiac leads in a single-center study
Human in  vivo data on the chemical stability of different transvenous lead materials, particularly OptimTM leads, are lacking. (Source: Heart Rhythm)
Source: Heart Rhythm - March 2, 2024 Category: Cardiology Authors: Rand Ibrahim, Kimberly Chaffin, Anand Shah, Stacy Westerman, Michael Lloyd, Neal Bhatia, Faisal M. Merchant, Mikhael El-Chami Source Type: research

Evaluation of the in-vivo Chemical Reactivity of a Novel Co-polymer Insulation on Cardiac Leads in a Single-Center Study
Human in-vivo data on the chemical stability of different transvenous lead materials and in particular Optim leads are lacking. (Source: Heart Rhythm)
Source: Heart Rhythm - March 2, 2024 Category: Cardiology Authors: Rand Ibrahim, Kimberly Chaffin, Anand Shah, Stacy Westerman, Michael Lloyd, Neal Bhatia, Faisal M. Merchant, Mikhael El-Chami Source Type: research

Corrigendum
In the editorial commentary titled “Is more, “more” when itcomes to pacing in heart transplant patients?” by J. Rod Gimbel published in February 2024 (2024;21;161-162) in Heart Rhythm, the surname of the related article’s first author, Zain Gowani, is incorrectly referred to as Gowali. This has been corrected in the online journal. The author regrets this error. (Source: Heart Rhythm)
Source: Heart Rhythm - March 1, 2024 Category: Cardiology Tags: Corrigendum Source Type: research

Optimal Cardiac Rhythm during Substrate Mapping in Scar-Related Ventricular Tachycardia: Significance of Wavefront Direction on Identifying Critical Sites
A rotational activation pattern (RAP) around the localized line of a conduction block often correlates with sites specific to the critical zones of ventricular tachycardia (VT). The wavefront direction during substrate mapping affects the manifestation of the RAP and line of block. (Source: Heart Rhythm)
Source: Heart Rhythm - March 1, 2024 Category: Cardiology Authors: Yasutoshi Shinoda, Yuki Komatsu, Masayuki Hattori, Yuka Oda, Yuto Iioka, Yuichi Hanaki, Hiro Yamasaki, Miyako Igarashi, Tomoko Ishizu, Akihiko Nogami Source Type: research

Electrocardiographic predictors of atrial mechanical sensing in leadless pacemakers
Leadless pacemakers (LP) capable of VDD pacing allow for atrioventricular synchrony through mechanical sensing of atrial contraction. Unfortunately, mechanical sensing is less reliable and less predictable than electrical sensing. (Source: Heart Rhythm)
Source: Heart Rhythm - March 1, 2024 Category: Cardiology Authors: Daniel Hofer, Fabrizio Perucchini, Hermann Blessberger, Clemens Steinwender, Samantha Zehetleitner, Nadine Molitor, Ardan M. Saguner, Mikhael F. El-Chami, George Black, Marco Schiavone, Giovanni Forleo, Alessio Gasperetti, Jan Steffel, Fabian Noti, Andrea Source Type: research

Wide QRS tachycardia with extreme QRS right-axis deviation
A 64-year-old man presented with epigastric discomfort and palpitations after consuming a festive meal. He reported taking no medications. Examination results were normal (with blood pressure of 120/70 mm Hg) except for tachycardia (Figure  1). What is the most likely diagnosis of the tachycardia? (Source: Heart Rhythm)
Source: Heart Rhythm - February 29, 2024 Category: Cardiology Authors: Bernard Belhassen, Ayelet Shauer Tags: Ecg Corner: Unknown of the Month Source Type: research

A Wide-QRS Tachycardia with an Extreme QRS Right Axis Deviation
A 64-year-old man presented with epigastric discomfort and palpitations after a festive meal. He reported taking no medications. His examination was normal (with a blood pressure of 120/70mmHg) except for tachycardia (Figure 1). (Source: Heart Rhythm)
Source: Heart Rhythm - February 29, 2024 Category: Cardiology Authors: Bernard Belhassen, Ayelet Shauer Source Type: research