Catheter Ablation Versus Medical Therapy for Atrial Fibrillation in Patients with Heart Failure with Preserved Ejection Fraction: A Systematic Review and Meta-analysis
The benefit of catheter ablation in patients with atrial fibrillation (AF) for patients with heart failure with preserved ejection fraction (HFpEF) remains uncertain. (Source: Heart Rhythm)
Source: Heart Rhythm - April 15, 2024 Category: Cardiology Authors: El ísio Bulhões, Vanio L.J. Antunes, Roberto Mazetto, Maria L.R. Defante, Anselmo C. Garcia, Camila Guida Source Type: research
Efficacy and safety of once-daily carvedilol in atrial fibrillation patients: a randomized, double-blind, placebo-controlled trial
Heart rate (HR) control is a mainstay of atrial fibrillation (AF) management. Guidelines recommend first-line β-blockers for HR control in paroxysmal, persistent, or permanent AF.1 Carvedilol, a non-selective β-blocker, has a documented HR-lowering effect; in a dose-escalation study of Japanese patients with chronic AF (AF Carvedilol study), each dose of carvedilol (5, 10 or 20 mg, once daily) significant ly reduced HR from baseline (HR ≥80 bpm) during 6 weeks of treatment.2 Although off-label carvedilol indications include AF,3 there are currently no phase 3 clinical trial data to support carvedilol use for HR control...
Source: Heart Rhythm - April 14, 2024 Category: Cardiology Authors: Jong-Il Choi, Yae Min Park, Yong-Seog Oh, Jin-Bae Kim, Seongwook Han, Jong-Sung Park, Young keun On, Kee-Joon Choi, Gyo-Seung Hwang, Moon-Hyoung Lee, Dong-Gu Shin, Nam-Ho Kim, Dae-Kyeong Kim, June Namgung, Dae-Hyeok Kim, Hyung-Wook Park, Hwan-Cheol Park, Source Type: research
Incidence of Newly Recognized Atrial Fibrillation in Patients with Obstructive Hypertrophic Cardiomyopathy Treated with Mavacamten
Mavacamten is a cardiac myosin inhibitor that has been shown to reduce left ventricular outflow tract obstruction in obstructive hypertrophic cardiomyopathy (oHCM).1 In late-stage clinical trials, atrial fibrillation (AF) represented an adverse event in 2-4 % of the patients randomized to mavacamten.1,2 However, the effect of mavacamten on the frequency and management of new/recurrent AF episodes in oHCM receiving mavacamten following its Food and Drug Administration (FDA) approval remains only partially explored. (Source: Heart Rhythm)
Source: Heart Rhythm - April 13, 2024 Category: Cardiology Authors: Matteo Castrichini, Said Alsidawi, Jeffrey B. Geske, Darrell B. Newman, Adelaide M. Arruda-Olson, J. Martijn Bos, Steve R. Ommen, Konstantinos C. Siontis, Michael J. Ackerman, John R. Giudicessi Source Type: research
Atrial Fibrillation Ablation in Patients with Pulmonary Hypertension: Multicenter Experience
Pulmonary hypertension (PH) is a progressive condition characterized by pulmonary vascular remodeling and elevated pulmonary arterial pressure. Atrial arrhythmias are common in PH and may contribute to right ventricular failure and death1,2. We retrospectively identified patients with pre-capillary PH who underwent catheter ablation for AF at four high-volume ablation centers. Included patients had an established clinical diagnosis of PH, with suspected pre-capillary etiology, and at least one right heart catheterization showing mean pulmonary artery pressure>20 mm Hg and pulmonary capillary wedge pressure ≤15 mm Hg. (Source: Heart Rhythm)
Source: Heart Rhythm - April 13, 2024 Category: Cardiology Authors: Thomas A. Boyle, Bao Ha, Ikram Haq, Ammar Killu, Ritu Yadav, David Spragg, Christopher X. Wong, Babikir Kheiri, Joshua D. Moss, Francis E. Marchlinski, David S. Frankel Source Type: research
Long-term outcomes after catheter ablation for idiopathic atypical atrial flutter
Idiopathic atypical (non-cavotricupid isthmus [CTI]-dependent) atrial flutter (IAAFL) may be seen in patients without structural heart disease and without previous cardiac surgery or ablation. (Source: Heart Rhythm)
Source: Heart Rhythm - April 12, 2024 Category: Cardiology Authors: Daisuke Yakabe, Kisho Ohtani, Masahiro Araki, Shujiro Inoue, Toshihiro Nakamura Source Type: research
Predicting Impaired Cardiopulmonary Exercise Capacity in Patients with Atrial Fibrillation Using a Simple Echocardiographic Marker
Exercise intolerance is a common symptom associated with atrial fibrillation (AF). However, echocardiographic markers that can predict impaired exercise capacity are lacking. (Source: Heart Rhythm)
Source: Heart Rhythm - April 11, 2024 Category: Cardiology Authors: Hung-Jui Chuang, Lung-Chun Lin, An-Li Yu, Yen-Bin Liu, Lian-Yu Lin, Hui-Chun Huang, Li-Ting Ho, Ling-Ping Lai, Wen-Jone Chen, Yi-Lwung Ho, Ssu-Yuan Chen, Chih-Chieh Yu Source Type: research
SCN5A gene variants and arrhythmic risk in Brugada Syndrome: an updated systematic review and meta-analysis
A rare gene variant in SCN5A can be found in approximately 20-25% of patients with Brugada syndrome (BrS). (Source: Heart Rhythm)
Source: Heart Rhythm - April 10, 2024 Category: Cardiology Authors: Ioannis Doundoulakis, Luigi Pannone, Sotirios Chiotis, Domenico Giovanni Della Rocca, Antonio Sorgente, Panagiotis Tsioufis, Alvise Del Monte, Giampaolo Vetta, Christos Piperis, Ingrid Overeinder, Gezim Bala, Alexandre Almorad, Erwin Str öker, Juan Sieir Source Type: research
Biomarkers to Predict Improvement of Left Ventricular Ejection Fraction after Atrial Fibrillation Ablation
Atrial fibrillation (AF) and heart failure (HF) frequently coexist. Prediction of left ventricular ejection fraction (LVEF) recovery after catheter ablation (CA) for AF remains difficult. (Source: Heart Rhythm)
Source: Heart Rhythm - April 10, 2024 Category: Cardiology Authors: Teodor Serban, Elisa Hennings, Ivo Strebel, Sven Knecht, Jeanne du Fay de Lavallaz, Philipp Krisai, Rebecca Arnet, Gian V öllmin, Stefan Osswald, Christian Sticherling, Michael Kühne, Patrick Badertscher Source Type: research
Pulsed-field vs. Cryoballoon vs. Radiofrequency ablation: outcomes after pulmonary vein isolation in patients with persistent atrial fibrillation
Pulsed-field ablation (PFA) has shown promising data in terms of safety and procedural efficiency for pulmonary vein isolation (PVI), with similar long-term outcomes compared to radiofrequency ablation (RFA) and cryoballoon ablation (CBA) in patient with paroxysmal atrial fibrillation (AF) (Source: Heart Rhythm)
Source: Heart Rhythm - April 10, 2024 Category: Cardiology Authors: Thomas Kueffer, Robin Stettler, Jens Maurhofer, Antonio Madaffari, Anita Stefanova, Salik ur Rehman Iqbal, Gregor Thalmann, Nikola A. Kozhuharov, Oskar Galuszka, Helge Servatius, Andreas Haeberlin, Fabian Noti, Hildegard Tanner, Laurent Roten, Tobias Reic Source Type: research
Acute Kidney Injury after Catheter Ablation of Atrial Fibrillation: Comparison between Different Energy Sources
Pulsed field ablation (PFA) is an innovative technology recently adopted for treating atrial fibrillation (AF). Preclinical and clinical studies have reported a reassuring safety profile because of its tissue-specific effect, sparing adjacent tissues.1 However, two cases of acute kidney injury (AKI) secondary to hemolysis after PFA have recently been reported after an uncommonly high number of applications.2,3 Similarly, a subsequent pilot study reported the occurrence of AKI in 4/28 patients after PFA for AF. (Source: Heart Rhythm)
Source: Heart Rhythm - April 10, 2024 Category: Cardiology Authors: Fabian Jordan, Sven Knecht, Corinne Isenegger, Rebecca Arnet, Philipp Krisai, Gian V öllmin, Jeanne du Fay de Lavallaz, David Spreen, Stefan Osswald, Christian Sticherling, Michael Kühne, Patrick Badertscher Source Type: research
Left bundle branch block-induced cardiomyopathy: a distinctive form of cardiomyopathy that might require a dedicated form of treatment.
The His-Purkinje system is the ventricular component of the cardiac conduction system that orchestrates the electrical impulse propagation which underlies every contraction of the heart. It originates from the AV-node and runs down to the interventricular septum and subdivides into the left and right bundle branches. These major branches divide further and spread diffusely along the sub endocardium. [1],[2] Damage in one of those branches may result in impaired electrical conduction. (Source: Heart Rhythm)
Source: Heart Rhythm - April 10, 2024 Category: Cardiology Authors: Manon Kloosterman, K.Peter Loh, Toon A.B. van Veen Source Type: research
Feasibility and efficacy of real-time ultrasound-guided venous closure with suture-mediated vascular closure device
Complications of venous vascular access are usually non-fatal but are the most common complications after transvenous catheter intervention. Vascular closure devices (VCD) have recently become available for venous closure. (Source: Heart Rhythm)
Source: Heart Rhythm - April 10, 2024 Category: Cardiology Authors: Masaya Tachi, Akihito Tanaka, Tsubasa Teraoka, Tappei Furuta, Etsushi Matsushita, Kazunori Hayashi, Masafumi Shimojo, Satoshi Yanagisawa, Yasuya Inden, Toyoaki Murohara Source Type: research
Relationship between wait-times and post-atrial fibrillation ablation outcomes: a population based study
Rhythm control is a cornerstone of atrial fibrillation (AF) management. Shorter time between diagnosis of AF and receipt of catheter ablation is associated with greater rates of therapy success. Prior work considered diagnosis-to-ablation time as a binary or categorical variable and did not consider the unique risk profile of patients once a referral for ablation is made. (Source: Heart Rhythm)
Source: Heart Rhythm - April 10, 2024 Category: Cardiology Authors: Denis Qeska, Feng Qiu, Ragavie Manoragavan, Harindra C. Wijeysundera, Christopher C. Cheung Source Type: research
Electrophysiologic mechanism and ablation strategy for macroreentrant biatrial tachycardias after Cox-maze procedures
Different types of recurrent atrial tachycardia (AT) after Cox-maze procedures have been reported, whereas biatrial tachycardia (BiAT) has not been systematically analyzed. (Source: Heart Rhythm)
Source: Heart Rhythm - April 9, 2024 Category: Cardiology Authors: Jinlin Zhang, Guanghui Cheng, Chenggang Deng, Anquan Zhao Source Type: research
Prognosis of patients in end-stage heart failure with atrial fibrillation treated with ablation: Insights from CASTLE-HTx
The CASTLE-HTx trial demonstrated the benefit of atrial fibrillation (AF) ablation compared with medical therapy in decreasing mortality, need for left ventricular assist device implantation, or heart transplantation (HTx) in patients with end-stage heart failure (HF). (Source: Heart Rhythm)
Source: Heart Rhythm - April 9, 2024 Category: Cardiology Authors: Maximilian Moersdorf, Jan G.P. Tijssen, Nassir F. Marrouche, Harry J.G.M. Crijns, Angelika Costard-Jaeckle, Leonard Bergau, Gerhard Hindricks, Nikolaos Dagres, Samuel Sossalla, Rene Schramm, Henrik Fox, Thomas Fink, Mustapha El Hamriti, Vanessa Sciacca, F Source Type: research
