Notable Papers
(Source: Heart Rhythm)
Source: Heart Rhythm - March 26, 2024 Category: Cardiology Source Type: research

Catheter-related and clinical complications associated with contact force –sensing irrigated ablation catheter
TactiFlex ™ Ablation Catheter, Sensor Enabled™ (Abbott, Minneapolis, MN) is an open-irrigation radiofrequency ablation catheter that merges contact force–sensing technology in a flexible tip design with real-time assessment of contact force vector and deflection indicator on the catheter tip. In additio n, the laser-cut flexible tip directs irrigation toward the area of greatest tissue contact, thus allowing more efficient cooling and less overall flow, facilitating high radiofrequency power delivery. (Source: Heart Rhythm)
Source: Heart Rhythm - March 26, 2024 Category: Cardiology Authors: Jakrin Kewcharoen, Kuldeep Shah, Rahul Bhardwaj, Mohit K. Turagam, Tahmeed Contractor, Ravi Mandapati, Dhanunjaya Lakkireddy, Jalaj Garg Tags: Research Letter Source Type: research

Catheter-related and Clinical Complications Associated with Contact Force-Sensing Irrigated Ablation Catheter
TactiFlex ™ Ablation Catheter, Sensor Enabled™ (Abbott,Minneapolis,MN) is an open-irrigation radiofrequency(RF) ablation catheter that merges contact force-sensing technology with a flexible tip design with real-time assessment of contact force vector and deflection indicator on the catheter tip.In additi on,the laser-cut flexible tip directs irrigation towards the area of greatest tissue contact thus allowing for more efficient cooling,less overall flow,and facilitates high RF power delivery.With continuous technological advances in catheter ablation,new device issues may arise with short- and long- term implications....
Source: Heart Rhythm - March 26, 2024 Category: Cardiology Authors: Jakrin Kewcharoen, Kuldeep Shah, Rahul Bhardwaj, Mohit K. Turagam, Tahmeed Contractor, Ravi Mandapati, Dhanunjaya Lakkireddy, Jalaj Garg Source Type: research

Pulsed Field Ablation: A Promise with Future Broad-based Applicability or a Pause needing Further Analysis
Recent scientific data has positioned pulsed-field ablation (PFA) as a possible replacement for traditional AF ablation approaches delivering radiofrequency or cryoablation thermal energy. PFA uses non-thermal, high-voltage electrical fields applied to cardiac tissue to create nanopores in the cellular membrane that disrupt cellular integrity, resulting in cellular necrosis and irreversible electroporation (IRE). (Source: Heart Rhythm)
Source: Heart Rhythm - March 26, 2024 Category: Cardiology Authors: Thomas F. Deering, T. Jared Bunch, Dhanunjaya Lakkireddy, Christopher F. Liu, Jonathan P. Piccini, Anne Marie Smith Source Type: research

To the Editor —Anterior mitral line and pulsed field ablation: Different energy source, similar results?
I read with great interest the paper by Wenzel and coworkers1 on the feasibility and efficacy of focal pulsed field ablation (PFA) for creating an anterior mitral line (AML) in 19 patients. The authors are to be congratulated on their innovative study, which establishes a new foundation for deploying an AML using a different energy source. In this context, it is important to compare this work with the most recent literature on AML using conventional radiofrequency (RF) ablation. (Source: Heart Rhythm)
Source: Heart Rhythm - March 21, 2024 Category: Cardiology Authors: Marco Bergonti Source Type: research

Reply to the Editor — Anterior mitral line and pulsed field ablation: Different energy source, similar results?
We would like to express our gratitude to Dr Bergonti for the valuable points of discussion regarding our manuscript “Repeat pulmonary vein isolation and anterior line ablation using a novel point-by-point pulsed-field ablation system.”1 We, too, have read his work on radiofrequency (RF) ablation of the anterior line with great interest.2 (Source: Heart Rhythm)
Source: Heart Rhythm - March 21, 2024 Category: Cardiology Authors: Bruno Reissmann, Jan-Per Wenzel, Marc D. Lemoine, Laura Rottner, Ilaria My, Fabian Moser, Julius Obergassel, Moritz Nies, Jan Rie ß, Djemail Ismaili, Julius Nikorowitsch, Paulus Kirchhof, Andreas Rillig, Andreas Metzner, Feifan Ouyang Source Type: research

Anterior Mitral Line and Pulsed Filed Ablation: different energy source, similar results?
We read with great interest the paper by Wenzel et al. on the feasibility and efficacy of focal pulsed-field ablation (PFA) for creating an anterior mitral line (AML) in 19 patients.1 The authors are to be congratulated on their innovative study, which establishes a new foundation for deploying an AML using a different energy source. In this context, it is important to compare this work with the most recent literature on AML using conventional radiofrequency (RF) ablation. (Source: Heart Rhythm)
Source: Heart Rhythm - March 21, 2024 Category: Cardiology Authors: Marco Bergonti Source Type: research

In Search of AV Synchrony
It is difficult to underestimate the impact of leadless pacemakers on cardiac rhythm management. The significant reduction in complications, which can exceed 60%1,2, appears to be predominantly related to a reduction in pocket infections, hematomas and the need for lead revisions. Patient satisfaction is harder to measure though equally impactful. The high implant success rate has led to the wide adoption of leadless technology. However, its initial single chamber design significantly limited the number of patients who could benefit due to the lack of atrioventricular synchrony (AVS). (Source: Heart Rhythm)
Source: Heart Rhythm - March 21, 2024 Category: Cardiology Authors: Larry Chinitz Source Type: research

Author ´s Reply to Anterior Mitral Line and Pulsed Filed Ablation: different energy source, similar results?
We would like to express our gratitude to Dr. Bergonti for the valuable points of discussion regarding our manuscript Repeat pulmonary vein isolation and anterior line ablation using a novel point-by-point pulsed-field ablation system.1 We too have read his work on RF ablation of the anterior line with great interest.2 (Source: Heart Rhythm)
Source: Heart Rhythm - March 21, 2024 Category: Cardiology Authors: Bruno Reissmann, Jan-Per Wenzel, Marc D. Lemoine, Laura Rottner, Ilaria My, Fabian Moser, Julius Obergassel., Moritz Nies, Jan Rie ß, Djemail Ismaili, Julius Nikorowitsch, Paulus Kirchhof, Andreas Rillig, Andreas Metzner, Feifan Ouyang Source Type: research

Relative contribution of contact force to lesion depth using high-power short-duration radiofrequency applications
High-power short-duration (HPSD) applications of radiofrequency (RF) electrical current are increasingly being used to create transmural lesions on the left atrial posterior wall. RF heats tissue by a combination of immediate resistive heating and delayed conductive heating, and the relative contribution of each has an impact on lesion geometry.1 Previous research has demonstrated wider, shallower lesions with HPSD, possibly minimizing injury to the esophagus.2 With resistive heating during the initial few seconds of lesion formation, contact force may not be as important in achieving the desired lesion depth; however, it ...
Source: Heart Rhythm - March 20, 2024 Category: Cardiology Authors: Nathaniel Steiger, Logan McClennen, Justin Bilenker, Lucas Vander Elst, Carlos Matos, Ely Gracia, Victor Nauffal, Paul C. Zei, Jorge E. Romero, William H. Sauer Tags: Research Letter Source Type: research

Relative Contribution of Contact Force to Lesion Depth Using High Power Short Duration Radiofrequency Applications
High Power Short Duration (HPSD) applications of radiofrequency (RF) electrical current are increasingly being used to create transmural lesions on the left atrial posterior wall. RF heats tissue via a combination of immediate resistive heating and delayed conductive heating and the relative contribution of each impacts lesion geometry.(1) Previous research has demonstrated wider, shallower lesions using HPSD, possibly minimizing injury to the esophagus.(2) With resistive heating during the initial few seconds of lesion formation, contact force may not be as important in achieving the desired lesion depth, however, it rema...
Source: Heart Rhythm - March 20, 2024 Category: Cardiology Authors: Nathaniel Steiger, Logan McClennen, Justin Bilenker, Lucas Vander Elst, Carlos Matos, Ely Gracia, Victor Nauffal, Paul C. Zei, Jorge E. Romero, William H. Sauer Source Type: research

Regional Differences in the Outcomes of Catheter Ablation for Ventricular Tachycardia in the United States
Earlier studies have shown regional variations in outcomes after invasive cardiovascular procedures (1). However, there is a paucity of such data concerning VT ablation in the United States. Therefore, we sought to analyze the regional differences in the in-hospital outcomes of patients undergoing VT ablation from a large nationally representative sample of the United States population. (Source: Heart Rhythm)
Source: Heart Rhythm - March 19, 2024 Category: Cardiology Authors: Siddharth Agarwal, Zain Ul Abideen Asad, Muhammad Bilal Munir, Gurukripa N. Kowlgi, Abhishek Deshmukh, Christopher V. DeSimone Source Type: research

To the Editor —Electrical impulse conduction through superior septal connections as a mechanism to bundle branch block correction is a verifiable assumption
When Karl Popper was asked how he would apply his falsifiability standard to the gravitational law espoused by Isaac Newton, he gave the example of an apple moving from the ground up to a branch and then dancing from one branch to another.1 His answer, obviously provided with tongue in cheek, reminds us that in science, philosophical postulates are best applied with restraint. The simpler explanation, offered without the need to make improbable assumptions and that does not ignore known facts, is usually closer to the truth. (Source: Heart Rhythm)
Source: Heart Rhythm - March 18, 2024 Category: Cardiology Authors: Rehan Mahmud, Damian Sanchez-Quintana, Yolanda Macias, Marcos C élio de Almeida, Robert H. Anderson, Eduardo Back Sternick Tags: Letter to the Editor Source Type: research

Effects of envelopes on cardiac implantable electronic device pocket healing: A head-to-head preclinical evaluation
The healing response to cardiac implantable electronic device (CIED) implantation results in inflammation that can lead to fibrous pocket formation, which may disrupt pocket healing or complicate future interventions. second-generation TYRX ™ absorbable antibacterial envelope (Source: Heart Rhythm)
Source: Heart Rhythm - March 18, 2024 Category: Cardiology Authors: Renu Virmani, Francois Philippon, Suneet Mittal, Aloke Finn, D ’Anne Kudlik, Nicole Kirchhof, Daniel Lexcen, John Kassotis Source Type: research

Effects of envelopes on CIED pocket healing: A head-to-head pre-clinical evaluation
The healing response to cardiac implantable electronic device (CIED) implantation results in inflammation that can result in fibrous pocket formation which may disrupt pocket healing or complicate future interventions. (Source: Heart Rhythm)
Source: Heart Rhythm - March 18, 2024 Category: Cardiology Authors: Renu Virmani, Francois Philippon, Suneet Mittal, Aloke Finn, D ’Anne Kudlik, Nicole Kirchhof, Daniel Lexcen, John Kassotis Source Type: research