A Wide-QRS Tachycardia with an Extreme QRS Right Axis Deviation
A 64-year-old man presented with epigastric discomfort and palpitations after a festive meal. He reported taking no medications. His examination was normal (with a blood pressure of 120/70mmHg) except for tachycardia (Figure 1). (Source: Heart Rhythm)
Source: Heart Rhythm - February 29, 2024 Category: Cardiology Authors: Bernard Belhassen, Ayelet Shauer Source Type: research
EP Corner: Oscillations
Electrophysiology study is performed for treatment of paroxysmal tachycardia. Wide and narrow QRS tachycardias are inducible with the transition captured in the tracing shown (Figure1). What is the mechanism of tachycardia and why does it terminate? (Source: Heart Rhythm)
Source: Heart Rhythm - February 29, 2024 Category: Cardiology Authors: William G. Stevenson, Travis D. Richardson Source Type: research
Symptomatic bradyarrhythmias in the athlete —Underlying mechanisms and treatments
Bradyarrhythmias including sinus bradycardia and atrioventricular (AV) block are frequently encountered in endurance athletes especially at night. While these are well tolerated by the young athlete, there is evidence that generally from the fifth decade of life onward, such arrhythmias can degenerate into pathological symptomatic bradycardia requiring pacemaker therapy. For many years, athletic bradycardia and AV block have been attributed to high vagal tone, but work from our group has questioned this widely held assumption and demonstrated a role for intrinsic electrophysiological remodeling of the sinus node and the AV...
Source: Heart Rhythm - February 28, 2024 Category: Cardiology Authors: Sami Al-Othman, Mark R. Boyett, Gwilym M. Morris, Aneil Malhotra, Pietro Mesirca, Matteo E. Mangoni, Alicia D ’Souza Tags: Contemporary Review Source Type: research
Symptomatic bradyarrhythmias in the athlete - underlying mechanisms and treatments
Bradyarrhythmias including sinus bradycardia and atrioventricular (AV) block are frequently encountered in endurance athletes especially at night. While these are well tolerated by the young athlete, there is evidence that generally from the fifth decade of life onwards, such arrhythmias can degenerate into pathological symptomatic bradycardia requiring pacemaker therapy. For many years, athletic bradycardia and AV block have been attributed to high vagal tone, but work from our group has questioned this widely-held assumption and demonstrated a role for intrinsic electrophysiological remodelling of the sinus node and the ...
Source: Heart Rhythm - February 28, 2024 Category: Cardiology Authors: Sami Al-Othman, Mark R. Boyett, Gwilym M. Morris, Aneil Malhotra, Pietro Mesirca, Matteo E. Mangoni, Alicia D ’Souza Source Type: research
Automated Electronic Alert for the Detection of Infected Cardiovascular Implantable Electronic Devices in Patients with Bacteremia
Cardiovascular implantable electronic device (CIED) infection is associated with high morbidity and mortality without proper treatment. Early transvenous lead extraction (TLE) has been associated with reduced adverse events and improved one-year survival1,2. However, a recent analysis of the Medicare database demonstrated that fewer than 20% of patients with CIED infection undergo TLE within 30 days of diagnosis3. While the etiology of delay is often multifactorial, a survey of 43 countries in the European Society of Cardiology reported over 50% of physicians felt a deficiency in knowledge and skills to make the diagnosis ...
Source: Heart Rhythm - February 28, 2024 Category: Cardiology Authors: Andrew Y. Lin, Francesca Torriani, Kevin Sung, Emily Trefethen, Nicholas Near, Gordon Ho, Travis Pollema, Ulrika Birgersdotter-Green Source Type: research
Complications of left bundle branch area pacing compared with biventricular pacing in candidates for resynchronization therapy: Results of a propensity score-matched analysis from a multicenter registry
Cardiac resynchronization therapy (CRT) with biventricular pacing (BVP) is a well-established therapy in patients with reduced left ventricular ejection fraction (LVEF), heart failure, and left bundle branch (LBB) block. LBB area pacing (LBBAP) has recently been shown to be a feasible and effective alternative to BVP. Comparative data on the risk of complications between LBBAP and BVP among patients undergoing CRT are lacking. (Source: Heart Rhythm)
Source: Heart Rhythm - February 28, 2024 Category: Cardiology Authors: Pietro Palmisano, Gabriele Dell ’Era, Federico Guerra, Ernesto Ammendola, Matteo Ziacchi, Mattia Laffi, Paolo Donateo, Alessandro Guido, Chiara Ghiglieno, Antonio Parlavecchio, Antonio Dello Russo, Gerardo Nigro, Mauro Biffi, Germano Gaggioli, Jacopo Se Source Type: research
Both HFpEF and HFmrEF should be included in calculating CHA2DS2-VASc score: A Taiwanese longitudinal cohort
Congestive heart failure (CHF) as a risk of stroke in patients with atrial fibrillation (AF) mainly referred to patients with left ventricular systolic dysfunction. Whether this should include patients with preserved ejection fraction is debatable. (Source: Heart Rhythm)
Source: Heart Rhythm - February 27, 2024 Category: Cardiology Authors: Chien-Chien Cheng, Pang-Shuo Huang, Jien-Jiun Chen, Fu-Chun Chiu, Sheng-Nan Chang, Yi-Chih Wang, Cho-Kai Wu, Juey-Jen Hwang, Chia-Ti Tsai Source Type: research
Impact of COVID-19 Pandemic on the Volume, Cost, and Outcomes of Cardiac Electrophysiology Procedures in the United States.
During the COVID-19 pandemic, professional societies recommended deferral of elective procedures for optimal resource utilization. (Source: Heart Rhythm)
Source: Heart Rhythm - February 27, 2024 Category: Cardiology Authors: Ahmed M. Altibi, Anas Hashem, Fares Ghanem, Saket Sanghai, Babak Nazer, Eric C. Stecker, Charles A. Henrikson Source Type: research
Both HFpEF and HFmrEF Should be Included in Calculating CHA2DS2 –VASc score: a Taiwanese Longitudinal Cohort
Congestive heart failure (CHF) as a risk of stroke in AF patients mainly referred to patients with left ventricular systolic dysfunction (HFrEF). Whether this should include patients with preserved ejection fraction (HFpEF) is debatable. (Source: Heart Rhythm)
Source: Heart Rhythm - February 27, 2024 Category: Cardiology Authors: Chien-Chien Cheng, Pang-Shuo Huang, Jien-Jiun Chen, Fu-Chun Chiu, Sheng-Nan Chang, Yi-Chih Wang, Cho-Kai Wu, Juey-Jen Hwang, Chia-Ti Tsai Source Type: research
Top stories in Wolff-Parkinson-White syndrome (2022 –2023)
The Copenhagen Baby Heart Study, a multicenter, prospective, population-based cohort study of 17,489 neonates younger than 30 days, identified 17 with a WPW pattern, a prevalence of 0.1%.1 This was more frequent in boys and was not associated with structural heart disease. Accessory pathways (APs) were primarily left-sided. At follow-up, the WPW pattern had disappeared in most, suggesting either an intermittent nature or that normalization occurs. (Source: Heart Rhythm)
Source: Heart Rhythm - February 26, 2024 Category: Cardiology Authors: Susan P. Etheridge, Maully Shah Tags: Top Stories: Pediatric Electrophysiology Source Type: research
Atrial fibrillation begets atrial fibrillation: The role of electroanatomic remodeling
Back in the early 1990s, it was generally believed that the transition from paroxysmal to permanent AF was due to aging and/or the effect of an underlying cardiovascular disease such as hypertension, valvular defects, or heart failure. At that time, we were involved in experimental studies of AF, and during one of our discussions, suddenly the question came up whether AF itself might have a deleterious effect on the atria. Once asked, this intriguing “what if” question could not be ignored and we decided to design a small pilot experiment to test the hypothesis. (Source: Heart Rhythm)
Source: Heart Rhythm - February 26, 2024 Category: Cardiology Authors: Maurits A. Allessie Tags: Iconic Figure Source Type: research
Top stories on gene therapy for genetic heart disease (2024)
Gene therapy is defined as the modification of gene expression via the introduction of therapeutic nucleic acid with the intention to treat or prevent disease. Mechanistically, gene therapy strategies aim to (1) replace/supplement a defective gene (eg, loss-of-function [LOF] disorders caused by haploinsufficiency) with a functional copy; (2) suppress/silence a defective gene (eg, gain-of-function [GOF] disorders); (3) suppress the normal and mutant allele and replace with normal gene in a hybrid manner (eg, for dominant negative LOF disorders); or (4) directly edit the genome to remove a disease-causative genetic lesion. (...
Source: Heart Rhythm - February 26, 2024 Category: Cardiology Authors: Michael J. Ackerman, John R. Giudicessi Tags: Top Stories: Clinical Electrophysiology Source Type: research
Editorial Board
(Source: Heart Rhythm)
Source: Heart Rhythm - February 26, 2024 Category: Cardiology Source Type: research
Table of Contents
(Source: Heart Rhythm)
Source: Heart Rhythm - February 26, 2024 Category: Cardiology Source Type: research
Reviewer Thanks
(Source: Heart Rhythm)
Source: Heart Rhythm - February 26, 2024 Category: Cardiology Source Type: research
