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Vinegar production and cancer risk
No abstract available (Source: European Journal of Cancer Prevention)
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Letters to the Editor Source Type: research

Folate intake and risk of esophageal cancer
No abstract available (Source: European Journal of Cancer Prevention)
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Letters to the Editor Source Type: research

The risk for childhood malignancies in the offspring of mothers with previous gestational diabetes mellitus: a population-based cohort study
The hyperglycemic intrauterine environment has been shown to have long-term effects on offspring. We aimed to evaluate its effect on the long-term risk of childhood malignancies. This was a population-based cohort analysis comparing the risk for long-term childhood malignancies (≤18 years) in children born to mothers with and without gestational diabetes mellitus (GDM). Childhood malignancies were diagnosed by physicians and recorded in hospital medical files according to predefined codes based on ICD-9. Deliveries occurred between the years 1991 and 2014 in a tertiary medical center. Children to mothers with pre-GDM, wi...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Registration Source Type: research

Cancer incidence in Mozambique in 2015–2016: data from the Maputo Central Hospital Cancer Registry
There is scarce information on cancer incidence in Mozambique. We aimed to describe cancer incidence data from the Cancer Registry of the Maputo Central Hospital (MCH) in 2015–2016, for Maputo City dwellers, and to compare the incidence rates with those observed in 1956–1961. Cancers with incidence data in 2015–2016 were identified by the Cancer Registry of the MCH. Crude and age-standardized incident rates (ASIR, per 100 000) – direct method, world standard population – were computed for Maputo City, under the assumption that most cancer cases among this population were identified at the MCH. A total of 1707 i...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Registration Source Type: research

Trace of survivin in cancer
Survivin is one of the most cancer-specific proteins overexpressed in almost all malignancies, but is nearly undetectable in most normal tissues in adults. Functionally, as a member of the inhibitor of apoptosis family, survivin has been shown to inhibit apoptosis and increase proliferation. The antiapoptotic function of survivin seems to be related to its ability to inhibit caspases directly or indirectly. Furthermore, the role of survivin in cell cycle division control is related to its role in the chromosomal passenger complex. Consistent with its determining role in these processes, survivin plays a crucial role in can...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Review Article: Carcinogenesis Source Type: research

The intervention mechanism of folic acid for benzo(a)pyrene toxic effects in vitro and in vivo
In conclusion, the mechanisms by which this effect is mediated were not entirely elucidated by our study, possibly because folic acid antagonizes the toxic effects of BaP by upregulating the levels of excision repair cross complementation group 1, xeroderma pigmentosum group A, and xeroderma pigmentosum group C gene expression to improve the rate of DNA repair, in turn accelerating the speed of repair for DNA damage caused by BaP. Meanwhile, folic acid could restrain BaP-induced cyclinD1 protein expression, which could help cells return to their normal cell cycle. (Source: European Journal of Cancer Prevention)
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Carcinogenesis Source Type: research

Race and renal cell carcinoma stage at diagnosis: an analysis of the Surveillance, Epidemiology, and End Results data
In conclusion, blacks were less likely to be diagnosed at a later stage RCC than Whites regardless of cancer histology. This racial disparity may exist over time during the study period. (Source: European Journal of Cancer Prevention)
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Urologic Cancer Source Type: research

Persistent organic pollutants, pesticides, and the risk of thyroid cancer: systematic review and meta-analysis
Previous epidemiological studies have reported persistent organic pollutants (POPs) and some nonpersistent pesticides and the risk of thyroid cancer. The aim of this study was to assess the association between exposure to POPs, pesticides, and thyroid cancer by carrying out a meta-analysis. Literature searches were performed using PubMed, Embase, and reference lists of relevant articles. Summary risk estimates for thyroid cancer were calculated using fixed-effects and random-effects models. In addition, several subgroup and sensitivity analyses were carried out. Fifteen studies were reviewed, and eight studies were include...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Head & Neck Cancer Source Type: research

Cervical cancer screening uptake in women aged between 15 and 64 years in Mozambique
Cervical cancer is the most common cancer in Mozambique, reflecting the high prevalence of both human papillomavirus and HIV infections. A national screening program for cervical cancer was started in 2009, using the visual inspection with acetic acid and cryotherapy, targeting women aged 30–55 years. We aimed to estimate the self-reported prevalence and determinants of cervical cancer screening uptake in Mozambique. A cross-sectional study of a representative sample of the women aged 15–64 years (n=1888) was carried out in 2014/2015 following the WHO-Stepwise Approach to Chronic Disease Risk Factor Surveillance. The p...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Gynecological Cancer Source Type: research

Changes in health behaviours and body mass index after a breast cancer diagnosis: results from a prospective cohort study
The aim of the study was to describe changes in health behaviours and BMI after breast cancer diagnosis, depicting the potential influence of sociodemographic, clinical and psychological characteristics. A total of 428 breast cancer patients were prospectively followed for 3 years, since diagnosis. At the end of follow-up, women were classified regarding their adherence to recommendations for cancer prevention, prediagnosis and after 3 years, including not smoking, alcohol consumption up to one drink per day, intake of at least five portions per day of fruits and/or vegetables, physical activity and body mass index (BMI) l...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Breast Cancer Source Type: research

Long-term sleep habits and the risk of breast cancer among Chinese women: a case–control study
Previous observational studies have inconsistently suggested that poor sleep is a novel risk factor for breast cancer (BC). However, these studies mainly focused on sleep duration; other sleep domains were rarely reported. The aim of this study was to evaluate the association of a broad range of sleep domains with the risk of BC incidence. We used a community-based 1 : 1 individual matched case–control design that included 401 female patients with incident BC and 401 age-matched and area-matched female controls in Jiujiang, China. Long-term sleep habits were assessed comprehensively using a validated 17-item Sleep Fa...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Breast Cancer Source Type: research

Genetic polymorphism of catechol-O-methyltransferase modulates the association of green tea consumption and lung cancer
Tea polyphenols are strong antioxidants, which can be rapidly O-methylated by catechol-O-methyltransferase (COMT). Thus, it is possible that the genetic polymorphism of COMT can modulate the association of green tea consumption and lung cancer. Here, we designed a case–control study to evaluate the combined effect of green tea consumption and COMT genotypes on the risk of lung cancer. A total of 237 lung cancer patients and 474 healthy controls were recruited. Questionnaires were administered to obtain demographic data, smoking status, green tea consumption, fruits and vegetables intake, exposure to cooking fumes, and fa...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Lung Cancer Source Type: research

Metformin for lung cancer prevention and improved survival: a novel approach
This study focuses on assessing metformin association with lung cancer as reported in the literature. Recent studies and reviews investigating metformin effects on lung cancer incidence and patient survival are critically and systematically discussed. (Source: European Journal of Cancer Prevention)
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Review Article: Lung Cancer Source Type: research

Red meat intake, CYP2E1 and PPARγ polymorphisms, and colorectal cancer risk
The association between red meat intake and colorectal cancer (CRC) may be modulated by genetic polymorphisms of cytochrome P450 2E1 (CYP2E1), a key enzyme in the metabolism of nitrosamines, and peroxisome proliferator-activated receptor gamma (PPARγ), a transcription factor involved in adipogenesis and lipid and glucose metabolism. We conducted a case–control study of 971 patients with CRC and 658 controls who were admitted to two university hospitals between 1995 and 2004 in Seoul, Korea. Participants were asked about red meat intake by using a validated food frequency questionnaire. Polymorphisms of CYP2E1 (rs3813867...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Gastrointestinal Cancer Source Type: research

Helicobacter pylori seroprevalence in Spain: influence of adult and childhood sociodemographic factors
Helicobacter pylori (H. pylori) chronic infection causes severe digestive diseases, including gastric cancer, and certain strains entail a higher risk. Risk factors for this infection are still not fully understood. The aim of this study was to describe the association of adult and childhood sociodemographic factors with the seroprevalence of H. pylori, and with CagA and VacA antigen-specific seropositivity among H. pylori-seropositive individuals in the Spanish adult population. Serum antibody reactivity to H. pylori proteins was evaluated using multiplex serology in 2555 population-based controls enrolled in the MCC-Spai...
Source: European Journal of Cancer Prevention - July 1, 2019 Category: Cancer & Oncology Tags: Research Papers: Gastrointestinal Cancer Source Type: research