Patients with gestational diabetes mellitus may be treated in both early and late pregnancy, especially in patients with pre-pregnancy overweight: A cross-sectional study in Japan
In conclusion, patients with GDM using the IADPSG criteria in early pregnancy may be treated, especially in patients with pre-pregnancy overweight. (Source: Diabetology International)
Source: Diabetology International - July 16, 2023 Category: Endocrinology Source Type: research
Correction: A consensus statement from the Japan Diabetes Society (JDS): a proposed algorithm for pharmacotherapy in people with type 2 diabetes
(Source: Diabetology International)
Source: Diabetology International - July 14, 2023 Category: Endocrinology Source Type: research
Association between dietary carbohydrate intake and risk of type 2 diabetes: a systematic review and meta-analysis of cohort studies
ConclusionsThis updated meta-analysis showed that, overall, carbohydrate intake is not associated with the risk of T2D; nevertheless, a significant association exists among Asian populations. To confirm the association between dietary carbohydrate intake and T2D risk observed in this study, further evidence from long-term observational studies of Asian populations is required. (Source: Diabetology International)
Source: Diabetology International - July 4, 2023 Category: Endocrinology Source Type: research
Impact of prediabetes with a high risk of diabetes stratified by glycated hemoglobin level on the severity of coronavirus disease 2019 during admission
ConclusionPrediabetes with a high risk of diabetes is associated with the worst COVID-19 symptom in terms of severity during admission. Our findings could aid in more efficient allocation of healthcare resources to a narrower population of prediabetic patients. (Source: Diabetology International)
Source: Diabetology International - July 1, 2023 Category: Endocrinology Source Type: research
Lost in translation: assessing the nomenclature change for diabetic kidney disease in Japan
AbstractRecently in Japan, the term"tonyobyo sei jinzobyo", the Japanese translation of"diabetic kidney disease", has been increasingly used in place of the term"tonyobyo sei jinsho", the Japanese translation of"diabetic nephropathy". Many international diabetes and nephrology guidelines have defined diabetic kidney disease as a condition caused by diabetes, typically presenting with albuminuria, similar to or identical to current and historical definitions for diabetic nephropathy. However, recent guidelines from the Japanese Society of Nephrology propose a broader disease concept f...
Source: Diabetology International - June 21, 2023 Category: Endocrinology Source Type: research
In vivo relationship between bound and free insulin in patients with diabetes having anti-insulin antibodies
ConclusionOur study suggests that the one-site (high-affinity site) of anti-insulin antibodies accounts, for the most part, for insulin pharmacokinetics within physiological insulin concentrations. (Source: Diabetology International)
Source: Diabetology International - June 20, 2023 Category: Endocrinology Source Type: research
Use of diabetes medications in adults with T2D and CVD in Japan: secondary analysis of the CAPTURE study
ConclusionThis analysis of the CAPTURE study provided a comprehensive overview of prescription patterns for the treatment of T2D in Japan. Use of GLAs with proven CV benefit was low, even in participants with established CVD, which was comparable to the findings from the global cohort. (Source: Diabetology International)
Source: Diabetology International - June 15, 2023 Category: Endocrinology Source Type: research
Glucose-lowering effects of semaglutide compared with dulaglutide using professional continuous glucose monitoring in outpatients with type 2 diabetes mellitus: a pilot study
ConclusionsSwitching from 0.75 mg DG to 0.5 mg SG in patients with T2DM improved glycemic variability, mean glycemic index, and daily variability without increasing the hypoglycemic index. The results suggest that switching to SG may be a useful option in patients experiencing inadequate glycemic control with DG. (Source: Diabetology International)
Source: Diabetology International - June 6, 2023 Category: Endocrinology Source Type: research
Anemia combined with albuminuria increases the risk of cardiovascular and renal events, regardless of a reduced glomerular filtration rate, in patients with type 2 diabetes: a prospective observational study
ConclusionAnemia combined with albuminuria is a risk factor for vascular events in patients with type 2 diabetes, regardless of the eGFR. (Source: Diabetology International)
Source: Diabetology International - May 30, 2023 Category: Endocrinology Source Type: research
Correction to: Role of insulin action in the pathogenesis of diabetic complications
(Source: Diabetology International)
Source: Diabetology International - May 27, 2023 Category: Endocrinology Source Type: research
Determinants of phase angle in Japanese patients with diabetes
AbstractPhase angle, obtained using bioelectrical impedance analysis, non-invasively reflects the whole-body cellular condition and nutritional status and may be helpful as a prognostic factor. Patients with diabetes had a smaller phase angle than healthy subjects. However, the clinical significance of phase angle has not yet been elucidated. Therefore, the purpose of this study was to clarify the relationship between phase angle and HbA1c in patients with diabetes and the clinical relevance of phase angle. A retrospective, multicenter, cross-sectional study was conducted with Japanese patients with diabetes. Body composit...
Source: Diabetology International - May 25, 2023 Category: Endocrinology Source Type: research
Hypertriglyceridemia contributes significantly to high prevalence of small dense LDL-cholesterol in patients with type 2 diabetes, even when LDL-C targets are achieved
ConclusionsThe TG cut-off for high-sdLDL-C was well below 150 mg/dL in a diabetic population. Amelioration of hypertriglyceridemia is needed even when LDL-C targets for diabetes are achieved. (Source: Diabetology International)
Source: Diabetology International - May 15, 2023 Category: Endocrinology Source Type: research
Concurrent bacterial liver abscess and mild encephalitis/encephalopathy with reversible splenial lesion in a patient with poorly controlled type 2 diabetes
AbstractA 34-year-old man with poorly controlled type 2 diabetes was admitted to our hospital because of fever, headache, vomiting, and impaired consciousness. His hemoglobin A1c level was as high as 11.0%. Abdominal computed tomography revealed a bacterial liver abscess, while head magnetic resonance imaging simultaneously showed a high-signal lesion on diffusion-weighted imaging and a low-signal lesion on the apparent diffusion coefficient map of the splenium of the corpus callosum. No significant findings were detected in the cerebrospinal fluid. The latter findings led to a diagnosis of mild encephalitis/encephalopathy...
Source: Diabetology International - May 15, 2023 Category: Endocrinology Source Type: research
Diabetic lipemia as a predisposing state to acute pancreatitis: a case report and literature review
We report the case of a 4-year-old girl with new-onset DKA associated with remarkable hypertriglyceridemia. Her serum triglyceride (TG) level was as high as 2490 mg/dL on admission and 11,072 mg/dL on day two during treatment with hydration and intravenous insulin infusion, whereas the critical situation was successfully stabilized by standard treatment for DKA without the occurrence of pancreatitis. We reviewed 27 cases of diabetic lipemia with or without pancreatitis that were described in the relevant literature to identify risk factors for the occurrence of pancreatitis in children with DKA. As a result, the severi...
Source: Diabetology International - April 29, 2023 Category: Endocrinology Source Type: research
Correction: Time course change of the insulin requirements during the perioperative period in hepatectomy and pancreatectomy by using an artificial pancreas STG-55
(Source: Diabetology International)
Source: Diabetology International - April 28, 2023 Category: Endocrinology Source Type: research
