Continuity of diabetes care among elderly Japanese patients: a medical record review study in a specialized diabetes clinic
ConclusionsOur findings indicated that continuous outpatient visits were difficult in elderly Japanese patients with diabetes. Older age ( ≥ 75 years) independently affected withdrawal. Future multicenter studies with adequate populations and social and geriatric factors are necessary to confirm our findings. (Source: Diabetology International)
Source: Diabetology International - January 24, 2022 Category: Endocrinology Source Type: research
Factors associated with atrial fibrillation in Japanese patients with type 2 diabetes mellitus: a cross-sectional study
ConclusionsOlder age, male sex, and reduced eGFR were associated with AF in Japanese patients with T2D. (Source: Diabetology International)
Source: Diabetology International - January 24, 2022 Category: Endocrinology Source Type: research
Incidence of interventions for diabetic retinopathy and serious lower-limb complications and its related factors in patients with type 2 diabetes using a real-world large claims database
ConclusionsWe showed the incidences of the first retinopathy interventions and lower-limb amputations and their secular trends in patients with diabetes, stratified by whether the antidiabetic medication was newly initiated or not. Older age, insulin use, and being dependents were risk factors of these interventions for diabetic complications. (Source: Diabetology International)
Source: Diabetology International - January 13, 2022 Category: Endocrinology Source Type: research
Effect of ultra-rapid insulin aspart on glycemic control in children with type 1 diabetes: the experience of a Portuguese tertiary centre
ConclusionAlthough the advantage of faster aspart had already been demonstrated in pediatric patients under MDI, “real-world” studies, including patients under CSII, are still lacking. This study highlights the important impact of faster aspart on metabolic control in children with T1D, particularly among adolescents under CSII. (Source: Diabetology International)
Source: Diabetology International - January 7, 2022 Category: Endocrinology Source Type: research
Leukocytic dysregulation in children with type 1 diabetes: relation to diabetic vascular complications
ConclusionChildren with T1D had significantly higher NLR and lower PLR compared to controls. These changes were more evident in those with diabetic microvascular complications than those without. Furthermore, NLR was positively correlated and PLR was negatively correlated to HbA1C, diabetes duration and hyperlipidemia. Hence, NLR and PLR can be a potential indicator for the risk of development of diabetic microvascular complications in children with T1D. (Source: Diabetology International)
Source: Diabetology International - January 7, 2022 Category: Endocrinology Source Type: research
Illness perception, medication adherence and glycemic control among primary health-care patients with type 2 diabetes mellitus at Port Said City, Egypt
ConclusionHigher HbA1c levels were linked to a higher BMI, a positive family history of T2DM, insulin users, high illness perception, and poor medication adherence. (Source: Diabetology International)
Source: Diabetology International - January 5, 2022 Category: Endocrinology Source Type: research
Correction to: Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity
(Source: Diabetology International)
Source: Diabetology International - December 7, 2021 Category: Endocrinology Source Type: research
Correction to: Decline in the estimated glomerular filtration rate (eGFR) following metabolic control and its relationship with baseline eGFR in type 2 diabetes with microalbuminuria or macroalbuminuria
(Source: Diabetology International)
Source: Diabetology International - November 27, 2021 Category: Endocrinology Source Type: research
Clinical practice of diabetic foot, nephropathy, and retinopathy in Japan: cross-sectional study using local and nationwide questionnaire surveys
ConclusionWe considered that interruption and non-attendance of eye examinations were a barrier to prevent severe retinopathy. Our results also suggested that some of the specialized facilities may be inadequate in their efforts to detect and prevent these complications. (Source: Diabetology International)
Source: Diabetology International - November 26, 2021 Category: Endocrinology Source Type: research
Correction to: Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity
(Source: Diabetology International)
Source: Diabetology International - November 26, 2021 Category: Endocrinology Source Type: research
Combined treatment with glucagon-like peptide-1 receptor agonist exendin-4 and metformin attenuates breast cancer growth
AbstractCancer is a major cause of death in patients with diabetes. Incretin therapy has received much attention because of its tissue-protective effects. We have previously reported an anti-breast cancer effect of glucagon-like peptide-1 receptor agonist exendin-4 (Ex-4). An anti-cancer effect of metformin is well recognized. Therefore, we examined the effect of combined treatment with Ex-4 and metformin in breast cancer cells. In human breast cancer cell lines MCF-7, MDA-MB-231, and KPL-1, 0.1 –10 mM metformin significantly reduced the cell number in growth curve analysis in a dose-dependent manner. Furthermore, combi...
Source: Diabetology International - November 25, 2021 Category: Endocrinology Source Type: research
Metabolic surgery in treatment of obese Japanese patients with type 2 diabetes: a joint consensus statement from the Japanese Society for Treatment of Obesity, the Japan Diabetes Society, and the Japan Society for the Study of Obesity
AbstractBariatric surgery has been shown to have a variety of metabolically beneficial effects for patients with type 2 diabetes (T2D), and is now also called metabolic surgery. At the 2nd Diabetes Surgery Summit held in 2015 in London, the indication for bariatric and metabolic surgery was included in the “algorithm for patients with type T2D”. With this background, the Japanese Society for Treatment of Obesity (JSTO), the Japan Diabetes Society (JDS) and the Japan Society for the Study of Obesity (JASSO) have formed a joint committee to develop a consensus statement regarding bariatric and metab olic surgery for the ...
Source: Diabetology International - November 8, 2021 Category: Endocrinology Source Type: research
Nurses ’ knowledge, attitude, and practice regarding oral management for outpatients with type 2 diabetes: a national survey on certified diabetes educators
AbstractThe association among certified diabetes educator nurses ’ knowledge, attitudes, and practices related to oral management has not been well examined. The aim of this study was to examine the association between knowledge and attitude as variables for nurses’ practice of oral management as certified diabetes educators at medical facilities in Japan. Th e questionnaires were administered to 300 certified diabetes educator nurses from 1277 medical facilities. The items regarding knowledge, attitude, and practice of oral management were assessed using items from the guidelines, reports, and books on diabetes and pe...
Source: Diabetology International - November 2, 2021 Category: Endocrinology Source Type: research
Current clinical state of type 1 diabetes in Saitama prefecture
ConclusionsThe glycemic control in T1D patients in Saitama was equivalent to that observed in previous nationwide surveys. Moreover, approximately one-quarter of T1D patients had obesity. Future studies should address whether our findings reflect those throughout Japan. (Source: Diabetology International)
Source: Diabetology International - November 1, 2021 Category: Endocrinology Source Type: research
Anthropometric measurements and serum TNF- α, IL-6 and adiponectin in type 2 diabetes
ConclusionsPrevention of obesity and central adiposity is an important factor to prevent elevations in inflammatory cytokine levels in diabetic patients. (Source: Diabetology International)
Source: Diabetology International - October 29, 2021 Category: Endocrinology Source Type: research
