Pseudolymphomatous Reaction to Red Tattoo Pigment
We describe the clinical, histological, and molecular aspects of a pseudolymphomatous reaction to red tattoo pigment.Case Rep Dermatol 2018;10:162 –168 (Source: Case Reports in Dermatology)
Source: Case Reports in Dermatology - June 14, 2018 Category: Dermatology Source Type: research
Bullous Pemphigoid as an Adverse Reaction to Pembrolizumab: Two Case Reports
We present 2 cases of bullous pemphigoid, as adverse reactions to pembrolizumab-treated MM.Case Rep Dermatol 2018;10:154 –157 (Source: Case Reports in Dermatology)
Source: Case Reports in Dermatology - June 5, 2018 Category: Dermatology Source Type: research
A Case of Annular Elastolytic Giant Cell Granuloma Associated with Syphilis
We report a case of 55-year-old man with AEGCG in association with syphilis, whose condition improved when hydroxychloroquine sulfate and topical tacrolimus were administered over a 2-month period.Case Rep Dermatol 2018;10:158 –161 (Source: Case Reports in Dermatology)
Source: Case Reports in Dermatology - June 5, 2018 Category: Dermatology Source Type: research
Efficacy and Tolerability of Topical Green Tea Extract (Polyphenon E) Application in a “Therapy-Resistant” Plantar Wart
Plantar warts account for 30% of all cutaneous warts. These lesions could be very painful, especially if the lesion is located over pressure sites such as the metatarsal head. Plantar wart treatment remains a challenging therapeutic problem. A 67-year-old immunocompetent nonsmoking man presented with a large mosaic plantar wart on his right foot. The lesion had been present for 5 years. Several cryotherapy sessions (a total of 6 procedures) had been performed with no success. The lesion was therefore treated with a 5-fluorouracil (5-FU) regimen and then with a topical combination of 5-FU and salicylic acid, but also these ...
Source: Case Reports in Dermatology - May 29, 2018 Category: Dermatology Source Type: research
Basal Cell Carcinoma Mimicking Desmoplastic Trichoepithelioma: A Case with Correlation of Dermoscopy and Histology
Basal cell carcinoma (BCC) is the most common cancer in humans worldwide. Many highly specific dermoscopic criteria for BCC are well established in the literature. On the contrary, other malignant or benign skin tumors may mimic BCC by exhibiting similar or even the same dermoscopic features and therefore obscuring the diagnosis of BCC in certain situations. We herein report a case of BCC with dermoscopic features of both BCC and desmoplastic trichoepithelioma (DT). We would like to remind of the often neglected differential diagnosis of DT in a lesion with arborizing vessels and otherwise unusual dermoscopic presentation....
Source: Case Reports in Dermatology - May 29, 2018 Category: Dermatology Source Type: research
Nevus Lipomatosis Cutaneous Superficialis: A Single-Center Case Series of 5 Patients
Conclusion: This is the first study about this rare type of skin tumor in Saudi Arabia and highlights the need for awareness of this clinical condition among dermatologists.Case Rep Dermatol 2018;10:138 –144 (Source: Case Reports in Dermatology)
Source: Case Reports in Dermatology - May 29, 2018 Category: Dermatology Source Type: research
Bullous Pemphigoid Associated with Adalimumab Therapy in a Patient with Ulcerative Colitis
Bullous pemphigoid (BP) is a blistering autoimmune disease mainly observed in elderly patients. Several triggers are known for this autoimmune disease and some drugs are known to be a cause of BP. However, there are only few case reports on the induction of BP under adalimumab therapy. Other autoimmune diseases, such as lupus erythematosus, are also known to occur under TNF inhibition. Here, we report on an 81-year-old patient who received adalimumab for ulcerative colitis and subsequently developed BP. Other causes of BP (tumors, other drugs, viral or toxoplasma infections) were excluded. We initiated a topical and system...
Source: Case Reports in Dermatology - May 29, 2018 Category: Dermatology Source Type: research
Methotrexate-Associated Lymphoproliferative Disorder: Dermoscopic Features
Methotrexate-related lymphoproliferative disorder (MTX-LPD) is a rare disorder caused by long-term MTX therapy for autoimmune diseases. There has been no report of the dermoscopic features of MTX-LPD to date. A 64-year-old female presented with a slightly elevated indurated erythematous plaque with scales on her right thigh. The patient had been treated for rheumatic arthritis with MTX and prednisolone for more than 15 years, and 18 mg/week MTX without prednisolone had been administered in the last year. Dermoscopy revealed dotted vessels and glomerular vessels on pink homogeneous areas and multiple surface scales. Enhance...
Source: Case Reports in Dermatology - May 29, 2018 Category: Dermatology Source Type: research
Porphyria Cutanea Tarda Presenting with Scleroderma, Ichthyosis, Alopecia, and Vitiligo
We report a complex case of PCT in a 67-year-old woman with an unusual constellation of cutaneous findings: scleroderma, acquired ichthyosis, and nonscarring alopecia. Possible triggers for her PCT include tamoxifen treatment for breast cancer and carrier status of the hemochromatosis gene. High-dose chloroquine was used to successfully achieve clinical remission and normalize her uroporphyrins. While on chloroquine she developed extensive classic vitiligo. It is not clear if this is another feature of her complex and unusual PCT, or a consequence of her antimalarial therapy.Case Rep Dermatol 2018;10:115 –121 (Source: Ca...
Source: Case Reports in Dermatology - May 17, 2018 Category: Dermatology Source Type: research
Chronic Prurigo: An Unusual Presentation of Hodgkin Lymphoma
Conclusion: This case report of chronic prurigo as the first manifestation of a systemic malignancy reminds us of the importance of a systematic diagnostic approach to this kind of patients initially and throughout time, especially if the symptoms do not respond to treatment. Our case may question the role of imaging examinations in the management and follow-up of a persistent prurigo nodularis.Case Rep Dermatol 2018;10:122 –126 (Source: Case Reports in Dermatology)
Source: Case Reports in Dermatology - May 17, 2018 Category: Dermatology Source Type: research
Anti-MDA5 Antibody-Positive Dermatomyositis Presenting with Cellulitis-Like Erythema on the Mandible as an Initial Symptom
We present here a 51-year-old Japanese woman with an anti-MDA5 antibody-positive DM who initially had cellulitis-like erythema on her right mandible. Histopathological findings showed a subcutaneous lobular infiltration of lymphocytes. The patient developed typical skin eruptions of DM/CADM, rapidly progressive interstitial lung disease, and severe muscle weakness 2 weeks after the first visit. After the diagnosis of anti-MDA5 antibody-positive DM, she was treated with intravenous steroid pulse therapy (methylprednisolone, 1,000 mg/day for 3 days), oral prednisolone at 1.0 mg/kg/day, and tacrolimus at 4.0 mg/day. The lesio...
Source: Case Reports in Dermatology - May 4, 2018 Category: Dermatology Source Type: research
Unilateral Focal Dermal Hypoplasia (Goltz Syndrome): Case Report and Literature Review
We report a case of unilateral FDH or Goltz syndrome in a 16-year-old girl presenting with hypopigmented-reticulated atrophic macules and patches in a linear pattern distributed along the lines of Blaschko over the right side of the face and the right arm. Also she is having hypoplasia of the right breast with dental enamel abnormality and partial anodontia in the lower jaw. Sparse hair and partial alopecia on the right side (scalp, eyebrows, and eyelashes) were also observed.Case Rep Dermatol 2018;10:101 –109 (Source: Case Reports in Dermatology)
Source: Case Reports in Dermatology - May 3, 2018 Category: Dermatology Source Type: research
Successful Treatment of Pityriasis Rubra Pilaris with Ixekizumab
Pityriasis rubra pilaris is an inflammatory dermatologic disorder of unknown cause and often confounded with psoriasis. It is characterised by hyperkeratotic follicular papules, scaly erythematous plaques, palmoplantar keratoderma, and a progression to generalised erythroderma. Here, we report the case of a 68-year-old man with pityriasis rubra pilaris, who was successfully treated with ixekizumab, an interleukin-17A inhibitor.Case Rep Dermatol 2018;10:97 –100 (Source: Case Reports in Dermatology)
Source: Case Reports in Dermatology - May 2, 2018 Category: Dermatology Source Type: research
Juvenile Localized Scleroderma with Hyaline Deposits in the Renal Arteriole
We report a 10-year-old boy with localized scleroderma of the linear and plaque type, who showed proteinuria and hematuria. In this patient, skin, articular, and renal manifestations appeared successively and then began to resolve in the same order. A renal biopsy specimen demonstrated mild mesangial cell proliferation, exudate of immunoglobulin in the glomerular capillary, and large electron-dense deposits in the afferent arteriole. We consider that there were some transient factors that had caused the skin and articular manifestations, which also induced renal vascular inflammatory responses.Case Rep Dermatol 2018;10:89 ...
Source: Case Reports in Dermatology - April 24, 2018 Category: Dermatology Source Type: research
Hereditary Leukonychia Totalis: A Case Report and Review of the Literature
We report a case of a 7-year-old Thai boy who developed asymptomatic white discoloration of all the nails since birth, with an absence of any predisposing factors or associated conditions.Case Rep Dermatol 2018;10:82 –88 (Source: Case Reports in Dermatology)
Source: Case Reports in Dermatology - April 12, 2018 Category: Dermatology Source Type: research
