In-Hospital Mortality and Major Adverse Cardiovascular Events after Kidney Transplantation in the United States
Conclusion: Despite increases in age at the time of KT, the absolute risk of perioperative MACEs has remained stable from 2004 to 2013. HF is a major component of postoperative MACEs in KT. Malnutrition and pulmonary hypertension are major nontraditional predictors of perioperative MACE outcomes.Cardiorenal Med 2019;9:51 –60 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - November 14, 2018 Category: Urology & Nephrology Source Type: research
Derived Subendocardial Viability Ratio and Cardiovascular Events in Patients with Chronic Kidney Disease
Conclusions: An SEVR #x3c; 130% predicts fatal and non-fatal cardiovascular events in non-dialysis CKD patients.Cardiorenal Med 2019;9:41 –50 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - November 8, 2018 Category: Urology & Nephrology Source Type: research
Enteral Baicalin, a Flavone Glycoside, Reduces Indicators of Cardiac Surgery-Associated Acute Kidney Injury in Rats
Conclusion: Our data indicated that baicalin mediated CPB/CA-induced AKI by decreasing the oxidative stress and inflammation in the renal tissues, and that baicalin possesses the potential to be developed as a therapeutic tool in clinical use for CSA-AKI.Cardiorenal Med 2019;9:31 –40 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - November 7, 2018 Category: Urology & Nephrology Source Type: research
Early Left Ventricular Dysfunction Detected by Speckle Tracking in Long-Term Hemodialysis Patients with Valvular Calcification
Conclusions: Cardiac VC diagnosed by echocardiography when it occurs in long-term hemodialysis patients may indicate more severe LVH, myocardial damage, and worse heart function in comparison to those without VC. Tissue Doppler imaging and 2D-STE can detect the subtle change of heart function in this population in the early stage of LV dysfunction when LVEF is normal.Cardiorenal Med 2019;9:22 –30 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - October 31, 2018 Category: Urology & Nephrology Source Type: research
Chronic Hyperkalemia in Cardiorenal Patients: Risk Factors, Diagnosis, and New Treatment Options
Chronic hyperkalemia (HK) is a serious medical condition that often manifests in patients with chronic kidney disease (CKD) and heart failure (HF) leading to poor outcomes and necessitating careful management by cardionephrologists. CKD, HF, diabetes, and renin-angiotensin-aldosterone system inhibitors use is known to induce HK. Current therapeutic options are not optimal, as pointed out by a large number of CKD and HF patients with HK. The following review will focus on the main risk factors for developing HK and also aims to provide a guide for a correct diagnosis and present new approaches to therapy.Cardiorenal Med 201...
Source: Cardiorenal Medicine - October 25, 2018 Category: Urology & Nephrology Source Type: research
Acknowledgement to the Reviewers
Cardiorenal Med 2018;8:340 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - October 10, 2018 Category: Urology & Nephrology Source Type: research
Contents Vol. 8, 2018
Cardiorenal Med 2018;8:I –V (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - October 10, 2018 Category: Urology & Nephrology Source Type: research
Impact of KDIGO-Defined Acute Kidney Injury on Mortality after Percutaneous Coronary Intervention for Acute Myocardial Infarction
Conclusion: A slight increase in serum creatinine was associated with a progressive increase in long-term mortality in patients with AKI according to the KDIGO definition.Cardiorenal Med 2018;8:332 –339 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - September 17, 2018 Category: Urology & Nephrology Source Type: research
Hepatorenal Syndrome or Hepatocardiorenal Syndrome: Revisiting Basic Concepts in View of Emerging Data
Background: Accumulating evidence on the pathophysiology of hepatorenal syndrome has challenged the conventional model of liver-kidney connection. While liver cirrhosis is traditionally considered the origin of a cascade of pathophysiologic mechanisms directly affecting other organs such as the kidney, emerging data point to the heart as the potential mediator of the untoward renal effects.Summary: Herein, we briefly review the often-overlooked contribution of the heart to circulatory dysfunction in hepatorenal syndrome and put forward evidence arguing for the involvement of systemic inflammation and endothelial dysfunctio...
Source: Cardiorenal Medicine - September 17, 2018 Category: Urology & Nephrology Source Type: research
Levels of Proinflammatory Cytokines, Oxidative Stress, and Tissue Damage Markers in Patients with Acute Heart Failure with and without Cardiorenal Syndrome Type 1
Conclusion: Patients affected by CRS type 1 present increased levels of proinflammatory cytokines and oxidative stress markers, increased levels of tissue damage markers, and lower hemoglobin levels. All these factors may be implicated in the pathophysiology of CRS type 1 syndrome.Cardiorenal Med 2018;8:321 –331 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - September 11, 2018 Category: Urology & Nephrology Source Type: research
Urine Cofilin-1 Detection for Predicting Type 1 Cardiorenal Syndrome in the Coronary Care Unit: A Gold Nanoparticle- and Laser-Based Approach
Conclusions: The gold nanoparticle-based immunoassay LSPCFB could exploit the potential of urine cofilin-1 as a single biomarker to predict CRS among CCU patients.Cardiorenal Med 2018;8:302 –310 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - August 17, 2018 Category: Urology & Nephrology Source Type: research
Relationship between Plasma Proprotein Convertase Subtilisin/Kexin Type 9 and Estimated Glomerular Filtration Rate in the General Chinese Population
Conclusion: In this single-center study with moderate sample size, the data showed no relationship of PCSK9 levels with normal or decreased eGFR in untreated patients with normal SCr, suggesting that further studies may be needed to understand the relationship between PCSK9 and lipid disorder in different stage of kidney dysfunction.Cardiorenal Med 2018;8:311 –320 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - August 17, 2018 Category: Urology & Nephrology Source Type: research
Cardionephrology: Proposal for a Futuristic Educational Approach to a Contemporary Need
The field of cardiorenal medicine is vast, rapidly expanding, and complex. Conventional nephrology training programs provide the fellows with the necessary core knowledge to provide general care for patients with renal and cardiovascular diseases. However, there is a need for focused training of interested physicians to master the specialized aspects of these exceedingly common clinical scenarios and optimize the care of such patients. A cardionephrology-focused training can add value to the nephrology subspecialty and potentially increase its attractiveness for a significant subset of trainees. Herein, we provide a propos...
Source: Cardiorenal Medicine - August 8, 2018 Category: Urology & Nephrology Source Type: research
Detection of Atherosclerotic Cardiovascular Disease in Patients with Advanced Chronic Kidney Disease in the Cardiology and Nephrology Communities
Conclusions: The survey results reveal a lack of consensus among providers caring for patients with advanced CKD about the management of ASCVD in this setting. Future randomized controlled trials will be needed to better inform the clinical management of ASCVD in these patients. The limitations of the study include its small sample size and the relatively low response rate among the respondents.Cardiorenal Med 2018;8:285 –295 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - August 3, 2018 Category: Urology & Nephrology Source Type: research
Hyponatremia in Acute Heart Failure in Relation to Hematocrit Levels: Clinical Relevance and Prognostic Implication
Conclusions: Low hematocrit levels in AHF patients with hyponatremia characterize a population that is more difficult to decongest and has poor clinical outcome. In contrast, patients with hyponatremia but normal hematocrit are better decongested and have better short-term outcome.Cardiorenal Med 2018;8:259 –270 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - July 25, 2018 Category: Urology & Nephrology Source Type: research
