Left Ventricular Strain and Dyssynchrony in Young and Middle-Aged Peritoneal Dialysis Patients and Healthy Controls: A Case-Matched Study
Conclusions: Despite preserved LVEF, young and middle-aged PD patients developed LV dysfunction and myocardial systolic dyssynchrony earlier compared with controls.Cardiorenal Med 2018;8:271 –284 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - July 25, 2018 Category: Urology & Nephrology Source Type: research
CXCL12 in Patients with Chronic Kidney Disease and Healthy Controls: Relationships to Ambulatory 24-Hour Blood Pressure and Echocardiographic Measures
Conclusions: The results of our study point towards a link between CXCL12 and LVH as well as blood pressure control among patients with CKD, supporting the thesis that CXCL12 may be regarded as a new potential uremic toxin.Cardiorenal Med 2018;8:249 –258 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - July 18, 2018 Category: Urology & Nephrology Source Type: research
Plasma Level of Retinol-Binding Protein 4, N-Terminal proBNP and Renal Function in Older Patients Hospitalized for Heart Failure
Conclusion: Our results show that RBP4 is affected by GFR but cannot be considered as an independent biomarker of heart muscle dysfunction.Cardiorenal Med 2018;8:237 –248 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - July 4, 2018 Category: Urology & Nephrology Source Type: research
Differential Impact of Chronic Kidney Disease on Coronary Calcification and Atherosclerosis in Asymptomatic Individuals with or without Diabetes: Analysis from a Coronary Computed Tomographic Angiography Registry
Conclusions: The presence of CKD did not have a significant impact on the development of coronary atherosclerosis, but affected the progression of coronary calcification more markedly from the stage of moderate CKD in nondiabetics. However, in diabetics, the deterioration of renal function was significantly associated with the development of coronary atherosclerosis and calcification from the stage of mild CKD.Cardiorenal Med 2018;8:228 –236 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - June 29, 2018 Category: Urology & Nephrology Source Type: research
Metabolic Syndrome and the Iodine-Dose/Creatinine Clearance Ratio as Determinants of Contrast-Induced Acute Kidney Injury
Conclusions: We showed that MetS is a strong risk factor for CI-AKI in nondiabetic patients undergoing elective coronary interventions; and the I-dose/CrCl ratio is a strong predictor of CI-AKI in these patients. We suggest that clinicians identify MetS patients and calculate their I-dose/CrCl ratio before coronary interventions.Cardiorenal Med 2018;8:217 –227 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - June 15, 2018 Category: Urology & Nephrology Source Type: research
Determinants of Monocyte Apoptosis in Cardiorenal Syndrome Type 1
Conclusion: CRS type 1 induces dual apoptotic pathway activation in monocytes; the two pathways converged on caspase-3. Many factors may induce activation of both intrinsic and extrinsic apoptotic pathways in CRS type 1 patients, such as upregulation of proinflammatory cytokines and hypoxia/ischemia. Further investigations are necessary to corroborate the present findings, and to better understand the pathophysiological mechanism and consequent therapeutic and prognostic implications for CRS type 1.Cardiorenal Med 2018;8:208 –216 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - May 30, 2018 Category: Urology & Nephrology Source Type: research
Epicardial Fat Thickness in Patients with Autosomal Dominant Polycystic Kidney Disease
Conclusion: Our data showed that EAT was higher in ADPKD patients than in EH subjects and independently correlated with LVMi. EAT measurement can be a useful marker for the cardiovascular risk stratification in ADPKD.Cardiorenal Med 2018;8:199 –207 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - May 4, 2018 Category: Urology & Nephrology Source Type: research
Revascularization versus Medical Management of Coronary Artery Disease in Prerenal Transplant Patients: A Meta-Analysis
Introduction: End-stage renal disease requiring renal transplantation comprises a growing patient population at risk for cardiovascular disease (CVD) morbidity and mortality in large part due to accelerated atherosclerosis. Consequently, these patients are at even higher risk of major surgical CVD mortality. A paucity of research has addressed the posttransplantation CVD outcomes related to different treatment strategies in this patient population and therefore, there are no specific preoperative guidelines regarding management of coronary artery disease in this high-risk population undergoing renal transplantation.Objecti...
Source: Cardiorenal Medicine - May 2, 2018 Category: Urology & Nephrology Source Type: research
ω-3 Polyunsaturated Fatty Acid Postconditioning Protects the Isolated Perfused Rat Heart from Ischemia-Reperfusion Injury
Conclusion:ω-3 PUFA postconditioning possesses good cardioprotective effects and may be developed into a therapeutic strategy for myocardial I/R injury.Cardiorenal Med 2018;8:173 –182 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - April 11, 2018 Category: Urology & Nephrology Source Type: research
Pulmonary Catherization Data Correlate Poorly with Renal Function in Heart Failure
Conclusion: These findings suggest that, as assessed by pulmonary artery catherization, none of the factors – PCWP, PASP, PADP, or CI – play a prominent role in cardiorenal syndromes.Cardiorenal Med 2018;8:183 –191 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - April 10, 2018 Category: Urology & Nephrology Source Type: research
Preeclampsia as a Form of Type 5 Cardiorenal Syndrome: An Underrecognized Entity in Women ’s Cardiovascular Health
Background: Preeclampsia is a multisystem vascular disorder of pregnancy that remains a leading cause of maternal and fetal morbidity and mortality. Preeclampsia remains an underrecognized risk factor for future cardiovascular and kidney disease in women and represents the confluence of preexisting vascular risk factors with superimposed endothelial injury from placental mediated anti-angiogenic factors.Summary: This review highlights the close relationship between preeclampsia and future cardiovascular and kidney disease. It describes the pathophysiology and current understanding of biomarkers that form the molecular sign...
Source: Cardiorenal Medicine - April 4, 2018 Category: Urology & Nephrology Source Type: research
Impact of Chronic Kidney Disease on Cardiovascular and Renal Events in Patients Undergoing Percutaneous Coronary Intervention with Everolimus-Eluting Stent: Risk Stratification with C-Reactive Protein
Conclusion: CKD combined with CRP predicted more clinical events in patients undergoing PCI with EES.Cardiorenal Med 2018;8:151 –159 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - March 27, 2018 Category: Urology & Nephrology Source Type: research
Personalized Statin Therapy and Coronary Atherosclerotic Plaque Burden in Asymptomatic Low/Intermediate-Risk Individuals
Conclusion: These findings suggest that individuals with higher coronary plaque burden are more likely to get greater benefit from statin therapy even among asymptomatic individuals with low cardiovascular risk.Cardiorenal Med 2018;8:140 –150 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - March 26, 2018 Category: Urology & Nephrology Source Type: research
lncRNA UCA1 Is a Novel Regulator in Cardiomyocyte Hypertrophy through Targeting the miR-184/HOXA9 Axis
Cardiac hypertrophy is closely associated with a series of cardiovascular diseases, including heart failure and sudden death in particular. An in-depth comprehension of the pathogenesis of cardiac hypertrophy will improve the diagnosis and therapy of cardiac hypertrophy. It has been acknowledged that long noncoding RNAs/microRNAs (lncRNAs/miRNAs) are crucial regulators in diverse biological processes, including various cardiovascular diseases, in multiple manners. Nevertheless, the biological roles of lncRNA UCA1 and miR-184 in cardiac hypertrophy are scarcely reported. In this paper, qRT-PCR analysis exhibited that lncRNA...
Source: Cardiorenal Medicine - March 21, 2018 Category: Urology & Nephrology Source Type: research
High Right Ventricular Stroke Work Index Is Associated with Worse Kidney Function in Patients with Heart Failure with Preserved Ejection Fraction
Conclusion: High right ventricular workload indicated by high RVSWI is associated with worse renal function in patients with Cpc-PH. Further prospective studies are needed to better understand this association.Cardiorenal Med 2018;8:123 –129 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - February 28, 2018 Category: Urology & Nephrology Source Type: research
