Target Hemoglobin May Be Achieved with Intravenous Iron Alone in Anemic Patients with Cardiorenal Syndrome: An Observational Study
Conclusion: Our observational study suggests that IV iron treatment without ESAs may substantially raise the Hb level to ≥11 g/dl in CRS patients. This treatment strategy may reduce the use of ESAs and hence its potential adverse effects.Cardiorenal Med 2015;5:246-253 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - July 4, 2015 Category: Urology & Nephrology Source Type: research
Influence of Chronic Kidney Disease on Physical Function and Quality of Life in Patients after Coronary Artery Bypass Grafting
Conclusion: Post-CABG patients with CKD had worse body composition, physical function, and QOL than those without CKD, and this might be associated with a worse NYHA class.Cardiorenal Med 2015;5:237-245 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - June 27, 2015 Category: Urology & Nephrology Source Type: research
Evidence of Mild Liver Dysfunction Identifies Stable Heart Failure Outpatients with Reversible Renal Dysfunction
Conclusions: Biochemical evidence of mild liver dysfunction is significantly associated with IRF in stable HF outpatients. Given the widespread availability and low cost of these markers, additional research is necessary to determine the utility of these parameters in identifying patients with reversible RD who may benefit from cardiorenal interventions.Cardiorenal Med 2015;5:229-236 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - June 6, 2015 Category: Urology & Nephrology Source Type: research
Contrast Medium-Induced Acute Kidney Injury
This article presents high-yield information on the above-mentioned aspects of CI-AKI, primarily based on results of randomised controlled trials, meta-analyses, systematic reviews and international consensus guidelines.Cardiorenal Med 2015;5:219-228 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - June 5, 2015 Category: Urology & Nephrology Source Type: research
Arrhythmogenic Remodeling in Murine Models of Deoxycorticosterone Acetate-Salt-Induced and 5/6-Subtotal Nephrectomy-Salt-Induced Cardiorenal Disease
Conclusion: DOCA-salt and SNx-salt treatment induced renal dysfunction, which resulted in structural and electrical cardiac remodeling and enhanced arrhythmogenicity. The reduced Cx43 expression and increased fibrosis levels in these hearts are likely candidates for the formation of the arrhythmogenic substrate.Cardiorenal Med 2015;5:208-218 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - June 5, 2015 Category: Urology & Nephrology Source Type: research
Comparison of Carvedilol and Metoprolol for Preventing Contrast-Induced Nephropathy after Coronary Angiography
Conclusion: When compared to metoprolol, carvedilol might decrease oxidative stress and subsequent development of CIN.Cardiorenal Med 2015;5:199-207 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - May 29, 2015 Category: Urology & Nephrology Source Type: research
Admission Glucose Levels and the Risk of Acute Kidney Injury in Nondiabetic ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
Conclusion: Severe admission hyperglycemia is an independent risk factor for the development of AKI among nondiabetic STEMI patients undergoing primary PCI.Cardiorenal Med 2015;5:191-198 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - May 29, 2015 Category: Urology & Nephrology Source Type: research
Ambulatory Blood Pressure Monitoring in Lean, Obese and Diabetic Children and Adolescents
Conclusion: Adolescent Ob and T2DM groups share adverse risk factors, which may be harbingers of adult cardiovascular events.Cardiorenal Med 2015;5:183-190 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - April 29, 2015 Category: Urology & Nephrology Source Type: research
Hyperuricemia: A Biomarker of Renal Hemodynamic Impairment
Background: Many epidemiological, clinical, and experimental reports have demonstrated an association between serum uric acid concentration and a variety of cardiovascular and renal diseases, particularly in hypertension. At present, there seems to be no resolution to the question whether this relationship is causal or coincidental. Summary: This discussion examines a number of biological, pathophysiological, fundamental, and clinical relationships between serum uric acid concentration and several of these disorders. To this end, discussion and review provide some specific insight conclusions and recommendations related to...
Source: Cardiorenal Medicine - April 24, 2015 Category: Urology & Nephrology Source Type: research
The Relationship between Serum Oxalic Acid, Central Hemodynamic Parameters and Colonization by Oxalobacter formigenes in Hemodialysis Patients
Conclusions: This is the first study that demonstrates the absence of O. formigenes as well as a relation between serum oxalic acid and cASBP, cADBP and PWV in HD patients. Replacement of O. formigenes with pre- and probiotics might decrease serum oxalic acid levels and improve cardiovascular outcomes in HD patients.Cardiorenal Med 2015;5:164-174 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - April 17, 2015 Category: Urology & Nephrology Source Type: research
Long-Term Risk of Progressive Chronic Kidney Disease in Patients with Severe Acute Kidney Injury Requiring Dialysis after Coronary Artery Bypass Surgery
Conclusion: Patients with severe AKI after CABG are at high risk of long-term renal dysfunction and should be monitored regularly for deterioration.Cardiorenal Med 2015;5:157-163 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - April 16, 2015 Category: Urology & Nephrology Source Type: research
Peritoneal Dialysis in Patients with Refractory Congestive Heart Failure: A Systematic Review
This study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. An electronic search of PubMed, Embase, and the Cochrane Library was performed to identify relevant studies published from January 1951 to February 2014. Eligible studies selected were prospective or retrospective adult population studies on PD in the setting of RCHF. The following clinical outcomes were used to assess PD therapy: (1) hospitalization rates; (2) heart function; (3) renal function; (4) fluid overload, and (5) adverse clinical outcomes. Summary: Of 864 citations, we excluded 843 citati...
Source: Cardiorenal Medicine - March 26, 2015 Category: Urology & Nephrology Source Type: research
Alteration of Cardiovascular Structure and Function in Patients Undergoing Peritoneal Dialysis
Conclusions: The results suggest several novel modifiable mechanisms related to the short-term effects of dialysis that are potentially implicated in the development of uremic cardiomyopathy.Cardiorenal Med 2015;5:135-144 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - March 24, 2015 Category: Urology & Nephrology Source Type: research
Effect of Contrast-Induced Nephropathy on the Long-Term Outcome of Patients with Non-ST Segment Elevation Myocardial Infarction
Conclusion: The effect of CIN on the long-term outcome of patients with NSTEMI was substantially influenced by confounding factors. CIN was a marker, rather than a mediator, of increased cardiovascular risk, and the baseline renal function was more conclusive as a long-term prognosticator.Cardiorenal Med 2015;5:116-124 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - February 27, 2015 Category: Urology & Nephrology Source Type: research
Direct Evidence of Podocyte Damage in Cardiorenal Syndrome Type 2: Preliminary Evidence
Conclusions: CRS-2 may be associated with glomerular damage as evidenced by an elevated urinary podocin/Cr ratio. Modulators of RAAS may have a protective effect on urinary podocin loss.Cardiorenal Med 2015;5:125-134 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - February 27, 2015 Category: Urology & Nephrology Source Type: research
