Elevated cystatin-C levels are associated with increased mortality in acute coronary syndrome patients: An HIJ-PROPER Sub-Analysis
Background and aims: We investigated the association between serum cystatin-C levels and cardiovascular events in patients with acute coronary syndrome. Methods: Data of 1,100 patients from the prospective parent study were included. Patients hospitalized for acute coronary syndrome were divided into four groups based on quartiles (Q) of cystatin-C levels (mg/L) within 24-hours of admission: Q1, ≤0.82; Q2, 0.82 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - February 9, 2022 Category: Urology & Nephrology Source Type: research

Clinical Utility of a Biomarker to Detect Contrast-Induced Acute Kidney Injury during Percutaneous Cardiovascular Procedures
Conclusion: This study suggests L-FABP as a clinical marker for assessing the risk of potential CI-AKI, has clinical utility, and can lead to more accurate diagnosis and treatment.Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - January 14, 2022 Category: Urology & Nephrology Source Type: research

Association of trimethylamine-N-oxide levels with risk of cardiovascular disease and mortality among elderly subjects: a systematic review and meta-analysis
Conclusions: The findings of this review revealed that the TMAO level is associated with all-cause mortality and adverse cardiovascular events. (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - December 16, 2021 Category: Urology & Nephrology Source Type: research

Acknowledgement to the Reviewers
Cardiorenal Med 2021;11:254 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - December 13, 2021 Category: Urology & Nephrology Source Type: research

Effect of Oral Hydration on Contrast-Induced Acute Kidney Injury among Patients after Primary Percutaneous Coronary Intervention
Conclusion: OHV/W ≥15.6 mL/kg for 24 h post-procedure may be an effective preventive strategy of CI-AKI. In addition, male patients may particularly benefit from OHV to prevent CI-AKI.Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - November 25, 2021 Category: Urology & Nephrology Source Type: research

Heart Failure in Patients with Diabetes and Chronic Kidney Disease: Challenges and Opportunities
Background: Heart failure (HF), diabetes mellitus (DM), and chronic kidney disease (CKD) are commonly occurring and interlinked conditions. Approximately 25% –40% of patients with HF have DM, and approximately 40%–50% of patients with HF have CKD. Both DM and CKD are associated with increased risk of incident HF. Furthermore, 40% of people with DM develop CKD, making DM the leading cause of kidney failure globally. Importantly, 16% of patients with H F have both comorbid DM and CKD, and the combination of these 3 comorbidities is associated with substantially increased risk for hospitalization and mortality. Mechanisms...
Source: Cardiorenal Medicine - November 19, 2021 Category: Urology & Nephrology Source Type: research

When Heart Failure Collides with Diabetes and Chronic Kidney Disease: Challenges and Opportunities
Background: Heart failure (HF), diabetes mellitus (DM), and chronic kidney disease (CKD) are commonly occurring and interlinked conditions. Approximately 25% to 40% of patients with HF have DM, and approximately 40% to 50% of patients with HF have CKD. Both DM and CKD are associated with increased risk of incident HF. Further, 40% of people with DM develop CKD, making DM the leading cause of kidney failure globally. Importantly, 16% of patients with HF have both comorbid DM and CKD, and the combination of these 3 comorbidities is associated with substantially increased risk for hospitalization and mortality. Mechanisms tha...
Source: Cardiorenal Medicine - November 19, 2021 Category: Urology & Nephrology Source Type: research

Effect of Beta-Blocker Cardioselectivity on Vascular Refilling in Hemodialysis Patients
Conclusions: Administering β-blockers before HD associated a higher risk of IDH and a decrease inFref. Patients dialyzed under carvedilol effect showed an impaired refilling, probably related to its noncardioselectivity and lower dializability.Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - November 16, 2021 Category: Urology & Nephrology Source Type: research

Patterns of Use and Clinical Outcomes with Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Acute Heart Failure and Changes in Kidney Function: An Analysis of the Veterans ’ Health Administrative Database
Conclusion: Higher SCr at admission is an important determinant of ACEI/ARB being discontinued or withheld in patients admitted with AHF. ACEI/ARB at discharge was associated with lower mortality in patients with AHF.Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - October 1, 2021 Category: Urology & Nephrology Source Type: research

The Role of Cell-Free Plasma DNA in Patients with Cardiorenal Syndrome Type 1
Conclusion: Our study explores the premise of cfDNA as a marker for apoptosis and inflammation in CRS type 1 patients. cfDNA could potentially serve as an index for noninvasive monitoring of tissue damage and apoptosis in patients with AKI induced by AHF.Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - September 9, 2021 Category: Urology & Nephrology Source Type: research

Editorial
Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - September 3, 2021 Category: Urology & Nephrology Source Type: research

The Association of Pre-Kidney Transplant Dialysis Modality with de novo Posttransplant Heart Failure
Conclusions: Our results suggest that choice of pretransplant dialysis modality may impact the development of posttransplant HF.Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - September 2, 2021 Category: Urology & Nephrology Source Type: research

Erratum
Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - August 24, 2021 Category: Urology & Nephrology Source Type: research

Major Adverse Renal and Cardiovascular Events following Intra-Arterial Contrast Media Administration in Hospitalized Patients with Comorbid Conditions
Conclusion: Intra-arterial administration using IOCM in at-risk patients is associated with lower rates of MARCE than the use of LOCM. This difference is especially apparent in patients with a combination of CKD 3 –4 and diabetes and in patients with CTO, providing real-world data validation with meaningful NNT in favor of IOCM.Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - August 12, 2021 Category: Urology & Nephrology Source Type: research

The Contribution of Known Familial Cardiovascular Disease Genes to Sudden Cardiac Death in Patients Undergoing Hemodialysis
Conclusions: We found no associations between genes known to be associated with ICCs and SCD in our sample of patients undergoing hemodialysis. This suggests that genetic causes are unlikely to be a major pathogenic factor in SCD in hemodialysis patients, although our sample size limits definitive conclusions.Cardiorenal Med (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - August 10, 2021 Category: Urology & Nephrology Source Type: research