Evaluation of the Predictive Value of the Serum Calcium-Magnesium Ratio for All-Cause and Cardiovascular Mortality in Incident Dialysis Patients
Conclusion: A high Ca-Mg ratio was significantly associated with all-cause and cardiovascular mortality, and it was more accurate than serum Mg.Cardiorenal Med 2018;8:50-60 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - October 25, 2017 Category: Urology & Nephrology Source Type: research
Acknowledgement to the Reviewers
Cardiorenal Med 2017;7:342 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - October 10, 2017 Category: Urology & Nephrology Source Type: research
Contents Vol. 7, 2017
Cardiorenal Med 2017;7:I-VI (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - October 10, 2017 Category: Urology & Nephrology Source Type: research
Evaluation of the Predictive Value of the Serum Calcium-Magnesium Ratio for All-Cause and Cardiovascular Mortality in Incident Dialysis Patients
Conclusion: A high Ca-Mg ratio was significantly associated with all-cause and cardiovascular mortality, and it was more accurate than serum Mg.Cardiorenal Med 2018;8:50-60 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - October 10, 2017 Category: Urology & Nephrology Source Type: research
Insulin Resistance in Kidney Disease: Is There a Distinct Role Separate from That of Diabetes or Obesity?
Insulin resistance is a central component of the metabolic dysregulation observed in obesity, which puts one at risk for the development of type 2 diabetes and complications related to diabetes such as chronic kidney disease. Insulin resistance and compensatory hyperinsulinemia place one at risk for other risk factors such as dyslipidemia, hypertension, and proteinuria, e.g., development of kidney disease. Our traditional view of insulin actions focuses on insulin-sensitive tissues such as skeletal muscle, liver, adipose tissue, and the pancreas. However, insulin also has distinct actions in kidney tissue that regulate gro...
Source: Cardiorenal Medicine - September 29, 2017 Category: Urology & Nephrology Source Type: research
Elevated Phosphate Levels Trigger Autophagy-Mediated Cellular Apoptosis in H9c2 Cardiomyoblasts
Conclusion: The results suggest that hyperphosphate in H9c2 cardiomyoblasts would lead to cellular apoptosis via autophagy, which is mediated by the pAMPK signaling pathway. Our findings revealed the possible mechanism responsible for the heart damage under hyperphosphatemia.Cardiorenal Med 2018;8:31-40 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - September 29, 2017 Category: Urology & Nephrology Source Type: research
Eicosapentaenoic Acid as a Potential Therapeutic Approach to Reduce Cardiovascular Risk in Patients with End-Stage Renal Disease on Hemodialysis: A Review
Background: Patients with end-stage renal disease on hemodialysis have excess cardiovascular disease (CVD) burden with substantially increased CV event rates compared with the general population.Summary: Traditional interventions that, according to standard clinical guidelines, reduce CV risk such as antihypertensive therapy, diet, exercise, and statins are not similarly effective in the hemodialysis population. This raises the question of whether additional risk factors, such as enhanced inflammation and oxidative stress, may drive the increased CVD burden in hemodialysis patients. Eicosapentaenoic acid (EPA), an omega-3 ...
Source: Cardiorenal Medicine - September 15, 2017 Category: Urology & Nephrology Source Type: research
Role of Body Mass Index in Acute Kidney Injury Patients after Cardiac Surgery
Background/Aims: To explore the association of body mass index (BMI) with the risk of developing acute kidney injury after cardiac surgery (CS-AKI) and for AKI requiring renal replacement therapy (AKI-RRT) after cardiac surgery.Methods: Clinical data of 8,455 patients undergoing cardiac surgery, including demographic preoperative, intraoperative, and postoperative data were collected. Patients were divided into underweight (BMI (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - September 15, 2017 Category: Urology & Nephrology Source Type: research
Relevance of Endothelial Cell-Specific Molecule 1 (Endocan) Plasma Levels for Predicting Pulmonary Infection after Cardiac Surgery in Chronic Kidney Disease Patients: The Endolung Pilot Study
Conclusion: This pilot study showed that a specific study to assess the link between endocan plasma levels and pulmonary infection after cardiac surgery in CKD patients is of potential utility.Cardiorenal Med 2018;8:1-8 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - August 30, 2017 Category: Urology & Nephrology Source Type: research
A Profile of Renal Function in Northern Cameroonians with Essential Hypertension
Background/Aim: The two-way cause and effect relationship existing between high blood pressure and kidney dysfunction is currently a well-documented phenomenon with patients in either category being almost equally predisposed to the other pathology. Our goal was to assess the renal function capacity of hypertensive patients in our setting.Methods: This cross-sectional descriptive study involved the determination of blood pressure levels and the collection of blood and urine samples for the measurement of renal function markers. Hypertensive patients who came for medical follow-up constituted the study participants, and wer...
Source: Cardiorenal Medicine - August 16, 2017 Category: Urology & Nephrology Source Type: research
One-Year Conservative Care Using Sodium Bicarbonate Supplementation Is Associated with a Decrease in Electronegative LDL in Chronic Kidney Disease Patients: A Pilot Study
Background: Chronic kidney disease (CKD) patients develop metabolic acidosis when approaching stages 3 and 4, a period in which accelerated atherogenesis may ensue. Studies in vitro show that low pH may increase low-density lipoprotein (LDL) oxidation, suggesting a role for chronic metabolic acidosis in atherosclerosis. The present study attempted to evaluate the effects of conservative care using oral sodium bicarbonate (NaHCO3) supplementation on the electronegative LDL [LDL(-)], a minimally oxidized LDL, plasma levels in CKD patients.Methods: Thirty-one CKD patients were followed by a multidisciplinary team during 15 mo...
Source: Cardiorenal Medicine - August 16, 2017 Category: Urology & Nephrology Source Type: research
Contrast-Induced Nephropathy Is Less Common in Patients with Good Coronary Collateral Circulation
Background/Aims: Contrast-induced nephropathy (CIN) is a typically reversible type of acute renal failure that develops after exposure to contrast agents; underlying endothelial dysfunction is thought to be an important risk factor for CIN. Although the mechanism of coronary collateral circulation (CCC) is not fully understood, a pivotal role of the endothelium has been reported in many studies. The aim of this study was to investigate whether there is a relationship between CCC and CIN.Methods: Patients with at least one occluded major coronary artery and blood creatinine analyses performed before and on the second day af...
Source: Cardiorenal Medicine - August 3, 2017 Category: Urology & Nephrology Source Type: research
Clinical Usefulness of Urinary Liver Fatty Acid-Binding Protein Excretion for Predicting Acute Kidney Injury during the First 7 Days and the Short-Term Prognosis in Acute Heart Failure Patients with Non-Chronic Kidney Disease
Conclusions: The u-LFABP level is an effective biomarker for predicting AKI during the first 7 days of hospitalization and an adverse outcome in AHF patients with non-CKD.Cardiorenal Med 2017;7:301-315 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - July 14, 2017 Category: Urology & Nephrology Source Type: research
The Relationship between Hypertriglyceridemic Waist Phenotype and Early Diabetic Nephropathy in Type 2 Diabetes
Conclusion: There was a significant correlation between HW phenotype and early diabetic nephropathy in type 2 diabetes.Cardiorenal Med 2017;7:295-300 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - July 12, 2017 Category: Urology & Nephrology Source Type: research
Long-Term Progression of Coronary Artery Calcification Is Independent of Classical Risk Factors, C-Reactive Protein, and Parathyroid Hormone in Renal Transplant Patients
Conclusion: CAC progression continued over the long-term follow-up of renal transplant patients. This phenomenon was unaccounted for by classical and nontraditional risk factors, as well as by biomarkers of renal dysfunction and renal damage.Cardiorenal Med 2017;7:284-294 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - July 12, 2017 Category: Urology & Nephrology Source Type: research
