Matrix Metalloproteinase Neutrophil Gelatinase-Associated Lipocalin Complex Predicts Atrial Fibrillation Recurrence after Electrical Cardioversion in Obese Patients
Conclusions: It is known that the greater the BMI at baseline, the higher the likelihood of progression from paroxysmal to permanent AF. However, European Society of Cardiology (ESC) guidelines do not consider obese patients a population with a low likelihood of success of cardioversion. That is why we need a sensitive marker to predict sinus rhythm maintenance in such a population. We found that MMP-NGAL complex may predict AF recurrence after successful cardioversion in obese patients.Cardiorenal Med 2017;7:11-20 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - August 11, 2016 Category: Urology & Nephrology Source Type: research
Aging Male Spontaneously Hypertensive Rat as an Animal Model for the Evaluation of the Interplay between Contrast-Induced Acute Kidney Injury and Cardiorenal Syndrome in Humans
Background: Although there are some animal models for biomarkers of contrast-induced acute kidney injury (CI-AKI), for cardiorenal syndrome (CRS) and for acute renal failure, the interplay between CI-AKI and CRS has yet to be evaluated. Insight into the pathogenesis of CRS is urgently needed from animal models in order to foster the discovery and implementation of novel biomarkers for this disease. Specially designed animal models for type 1 and 3 CRS, particularly CI-AKI, have not yet emerged. Summary: We hypothesize that the aging male spontaneously hypertensive rat (SHR) is likely to be a suitable model. The SHR model i...
Source: Cardiorenal Medicine - July 20, 2016 Category: Urology & Nephrology Source Type: research
Evaluation of Nephroprotective Efficacy of Hypoxic Preconditioning in Patients Undergoing Coronary Artery Bypass Surgery
Conclusion: The results of our study showed that (i) HP exerts nephroprotection in patients undergoing on-pump CABG, and (ii) determination of the lipocalin-2 level can be used for early diagnosis of acute kidney injury in cardiac surgery patients.Cardiorenal Med 2016;6:328-336 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - June 22, 2016 Category: Urology & Nephrology Source Type: research
High-NaCl Diet Aggravates Cardiac Injury in Rats with Adenine-Induced Chronic Renal Failure and Increases Serum Troponin T Levels
Conclusion: Two weeks of high-NaCl diet in rats with ACRF produces LV injury and aggravates increases in serum cTnT levels, presumably by causing hypertension-induced small artery lesions leading to myocardial ischemia. This model may be suitable for studying pathophysiological mechanisms in chronic renicardiac syndromes.Cardiorenal Med 2016;6:317-327 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - June 22, 2016 Category: Urology & Nephrology Source Type: research
Brain Natriuretic Peptide and Body Fluid Composition in Patients with Chronic Kidney Disease: A Cross-Sectional Study to Evaluate the Relationship between Volume Overload and Malnutrition
Conclusion: Fluid volume imbalance between intra- and extracellular water regulated by decreased cell mass was independently associated with BNP levels, which may explain the reserve capacity for fluid accumulation in patients with CKD.Cardiorenal Med 2016;6:337-346 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - June 22, 2016 Category: Urology & Nephrology Source Type: research
Association between Age at Menarche and Cardiovascular Disease Risk Factors in China: A Large Population-Based Investigation
Conclusions: Earlier AAM were positively associated with incident CVD events, hypertension and ‘college or above' educational level.Cardiorenal Med 2016;6:307-316 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - May 25, 2016 Category: Urology & Nephrology Source Type: research
Genetic Variants in Toll-Like Receptor 4 Gene and Their Association Analysis with Estimated Glomerular Filtration Rate in Mexican American Families
Conclusion: We show for the first time that Asp(299)Gly variants of TLR4 are associated with decrease in renal function in Mexican Americans.Cardiorenal Med 2016;6:301-306 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - May 20, 2016 Category: Urology & Nephrology Source Type: research
Association of Inflammation prior to Kidney Transplantation with Post-Transplant Diabetes Mellitus
Conclusion: Our in vitro and clinical observations suggest that TNFα could contribute to PTDM through an effect on adiponectin. Our study proposes that inflammation is involved in glucose regulation after kidney transplantation.Cardiorenal Med 2016;6:289-300 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - May 17, 2016 Category: Urology & Nephrology Source Type: research
Predictive Value of the Mehran Score for Contrast-Induced Nephropathy after Transcatheter Aortic Valve Implantation in Patients with Aortic Stenosis
Conclusion: MS is a predictor of CIN development after TAVI. We think that the use of MS in clinical practice may decrease renal complications after TAVI.Cardiorenal Med 2016;6:279-288 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - May 4, 2016 Category: Urology & Nephrology Source Type: research
Impact of Cardiorenal Anemia Syndrome on Short- and Long-Term Clinical Outcomes in Patients Hospitalized with Heart Failure
Background: Dysfunctional interplay between the heart and kidneys may lead to the development of anemia. The aim of this study was to evaluate the impact of cardiorenal anemia syndrome (CRAS) on short- and long-term outcomes among patients hospitalized with heart failure (HF). Methods: We enrolled 303 patients hospitalized with HF. We divided the patients into two groups: a CRAS group (n = 64) and a non-CRAS group (n = 239). We defined CRAS as HF accompanied by (1) an estimated glomerular filtration rate (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - April 28, 2016 Category: Urology & Nephrology Source Type: research
Beta-Blocker Use Is Associated with Higher Renal Tissue Oxygenation in Hypertensive Patients Suspected of Renal Artery Stenosis
Conclusions: In addition to known benefits to reduce cardiovascular mortality in patients with renal disease, beta-blockers may reduce or prevent the progression of renal dysfunction in patients with hypertension, diabetes, and renovascular disease, partly by reducing renal oxygen consumption. These observations may have important implications for the treatment of patients with CKD.Cardiorenal Med 2016;6:261-268 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - April 22, 2016 Category: Urology & Nephrology Source Type: research
Angiogenic Factors and Risks of Technique Failure and Cardiovascular Events in Patients Receiving Peritoneal Dialysis
Conclusion: Elevated PlGF and sFlt-1 are significantly associated with high transport membrane status. PlGF may be a useful predictor of technique survival and cardiovascular events in PD patients.Cardiorenal Med 2016;6:251-259 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - March 30, 2016 Category: Urology & Nephrology Source Type: research
Risk Factors for Acute Kidney Injury after Cardiovascular Surgery: Evidence from 2,157 Cases and 49,777 Controls - A Meta-Analysis
Conclusions: Our results support that preoperative, intraoperative, and postoperative factors are associated with AKI-CS. Ejection fraction, BMI, acute myocardial infarction, type of surgery, and congestive heart failure were not absolutely associated with AKI.Cardiorenal Med 2016;6:237-250 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - March 17, 2016 Category: Urology & Nephrology Source Type: research
Clinical and Echocardiographic Factors Associated with Right Ventricular Systolic Dysfunction in Hemodialysis Patients
Background: Chronic kidney disease is a disorder of epidemic proportions that impairs cardiac function. Cardiovascular diseases are the leading cause of death in hemodialysis patients, and the understanding of new nontraditional predictors of mortality could improve their outcomes. Right ventricular systolic dysfunction (RVSD) has recently been recognized as a predictor of cardiovascular death in heart failure and hemodialysis patients. However, the factors contributing to RVSD in hemodialysis patients remain unknown. The aim of this study was to evaluate the clinical and echocardiographic factors associated with RVSD in h...
Source: Cardiorenal Medicine - March 10, 2016 Category: Urology & Nephrology Source Type: research
Risk Factors for Acute Kidney Injury after Coronary Artery Bypass Surgery and Its Detection Using Neutrophil Gelatinase-Associated Lipocalin
Conclusion: The number of stenotic coronary arteries, EF, CCA-IMT and HCT are all important risk factors. Early postoperative NGAL results were highly specific for the early recognition of AKI.Cardiorenal Med 2016;6:216-229 (Source: Cardiorenal Medicine)
Source: Cardiorenal Medicine - March 10, 2016 Category: Urology & Nephrology Source Type: research
