Potential role of anti-Idiotype responses on the neurological effects of post-acute sequelae of COVID-19 (PASC)
Brain Behav Immun. 2023 Dec 18:S0889-1591(23)00399-9. doi: 10.1016/j.bbi.2023.12.017. Online ahead of print.NO ABSTRACTPMID:38123027 | DOI:10.1016/j.bbi.2023.12.017 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 20, 2023 Category: Neurology Authors: William J Murphy Craig P Collins Paul Ashwood Source Type: research
Microglia and age-related cognitive decline: Primed for sex differences
Brain Behav Immun. 2023 Dec 12:S0889-1591(23)00382-3. doi: 10.1016/j.bbi.2023.12.011. Online ahead of print.NO ABSTRACTPMID:38096924 | DOI:10.1016/j.bbi.2023.12.011 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 14, 2023 Category: Neurology Authors: Benedetta Leuner Source Type: research
Microglia and age-related cognitive decline: Primed for sex differences
Brain Behav Immun. 2023 Dec 12:S0889-1591(23)00382-3. doi: 10.1016/j.bbi.2023.12.011. Online ahead of print.NO ABSTRACTPMID:38096924 | DOI:10.1016/j.bbi.2023.12.011 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 14, 2023 Category: Neurology Authors: Benedetta Leuner Source Type: research
Microglia and age-related cognitive decline: Primed for sex differences
Brain Behav Immun. 2023 Dec 12:S0889-1591(23)00382-3. doi: 10.1016/j.bbi.2023.12.011. Online ahead of print.NO ABSTRACTPMID:38096924 | DOI:10.1016/j.bbi.2023.12.011 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 14, 2023 Category: Neurology Authors: Benedetta Leuner Source Type: research
Microglia and age-related cognitive decline: Primed for sex differences
Brain Behav Immun. 2023 Dec 12:S0889-1591(23)00382-3. doi: 10.1016/j.bbi.2023.12.011. Online ahead of print.NO ABSTRACTPMID:38096924 | DOI:10.1016/j.bbi.2023.12.011 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 14, 2023 Category: Neurology Authors: Benedetta Leuner Source Type: research
Microglia and age-related cognitive decline: Primed for sex differences
Brain Behav Immun. 2023 Dec 12:S0889-1591(23)00382-3. doi: 10.1016/j.bbi.2023.12.011. Online ahead of print.NO ABSTRACTPMID:38096924 | DOI:10.1016/j.bbi.2023.12.011 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 14, 2023 Category: Neurology Authors: Benedetta Leuner Source Type: research
Interleukin-10 signaling in somatosensory neurons controls CCL2 release and inflammatory response
In conclusion, we showed that IL-10 binds to its receptor on sensory neurons to downregulate CCL2 and contribute to immunoregulation by reducing the attraction of immune cells by DRG neuron-derived CCL2. This is the first evidence that anti-inflammatory cytokines limit inflammation through direct binding to receptors on sensory neurons. Our data also add to the growing literature that sensory neurons have immunomodulatory functions.PMID:38081433 | DOI:10.1016/j.bbi.2023.12.013 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 11, 2023 Category: Neurology Authors: Sabrina de Souza Jes ús Rosario-Claudio Jaewon Sim Kufreobong E Inyang Andrew Dagenais Karli Monahan Beenhwa Lee Hariharan Ramakrishnan Visha Parmar Matan Geron Gr égory Scherrer Joseph K Folger Geoffroy Laumet Source Type: research
Association of persistent musculoskeletal pain with dementia risk score in adults aged 45 years or older: The China health and retirement longitudinal study
CONCLUSIONS: Promoting the management of musculoskeletal pain may be beneficial in reducing the dementia risk score.PMID:38081434 | DOI:10.1016/j.bbi.2023.12.015 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 11, 2023 Category: Neurology Authors: Ya-Nan Zheng Hui Liu Pei-Jie Chen Xue-Qiang Wang Source Type: research
Neuroimmune activation and increased brain aging in chronic pain patients after the COVID-19 pandemic onset
This study underscores the broad impact of the pandemic on human health, which extends beyond the morbidity solely mediated by the virus itself.PMID:38081435 | DOI:10.1016/j.bbi.2023.12.016 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 11, 2023 Category: Neurology Authors: Ludovica Brusaferri Zeynab Alshelh Jack H Schnieders Angelica Sandstr öm Mehrbod Mohammadian Erin J Morrissey Minhae Kim Courtney A Chane Grace C Grmek Jennifer P Murphy Julia Bialobrzewski Alexa DiPietro Julie Klinke Yi Zhang Angel Torrado-Carvajal Nath Source Type: research
The biology of hope: Inflammatory and neuroendocrine profiles in ovarian cancer patients
CONCLUSIONS: These data suggest a biological signature of hope associated with less inflammation and more normalized diurnal cortisol in ovarian cancer. These findings have potential clinical utility but need replication with more diverse samples and validated assessments of hope.PMID:38081436 | DOI:10.1016/j.bbi.2023.12.014 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 11, 2023 Category: Neurology Authors: Susan K Lutgendorf Rachel M Telles Brendan Whitney Premal H Thaker George M Slavich Michael J Goodheart Frank J Penedo Alyssa E Noble Steven W Cole Anil K Sood Benjamin W Corn Source Type: research
Interleukin-10 signaling in somatosensory neurons controls CCL2 release and inflammatory response
In conclusion, we showed that IL-10 binds to its receptor on sensory neurons to downregulate CCL2 and contribute to immunoregulation by reducing the attraction of immune cells by DRG neuron-derived CCL2. This is the first evidence that anti-inflammatory cytokines limit inflammation through direct binding to receptors on sensory neurons. Our data also add to the growing literature that sensory neurons have immunomodulatory functions.PMID:38081433 | DOI:10.1016/j.bbi.2023.12.013 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 11, 2023 Category: Neurology Authors: Sabrina de Souza Jes ús Rosario-Claudio Jaewon Sim Kufreobong E Inyang Andrew Dagenais Karli Monahan Beenhwa Lee Hariharan Ramakrishnan Visha Parmar Matan Geron Gr égory Scherrer Joseph K Folger Geoffroy Laumet Source Type: research
Association of persistent musculoskeletal pain with dementia risk score in adults aged 45 years or older: The China health and retirement longitudinal study
CONCLUSIONS: Promoting the management of musculoskeletal pain may be beneficial in reducing the dementia risk score.PMID:38081434 | DOI:10.1016/j.bbi.2023.12.015 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 11, 2023 Category: Neurology Authors: Ya-Nan Zheng Hui Liu Pei-Jie Chen Xue-Qiang Wang Source Type: research
Neuroimmune activation and increased brain aging in chronic pain patients after the COVID-19 pandemic onset
This study underscores the broad impact of the pandemic on human health, which extends beyond the morbidity solely mediated by the virus itself.PMID:38081435 | DOI:10.1016/j.bbi.2023.12.016 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 11, 2023 Category: Neurology Authors: Ludovica Brusaferri Zeynab Alshelh Jack H Schnieders Angelica Sandstr öm Mehrbod Mohammadian Erin J Morrissey Minhae Kim Courtney A Chane Grace C Grmek Jennifer P Murphy Julia Bialobrzewski Alexa DiPietro Julie Klinke Yi Zhang Angel Torrado-Carvajal Nath Source Type: research
The biology of hope: Inflammatory and neuroendocrine profiles in ovarian cancer patients
CONCLUSIONS: These data suggest a biological signature of hope associated with less inflammation and more normalized diurnal cortisol in ovarian cancer. These findings have potential clinical utility but need replication with more diverse samples and validated assessments of hope.PMID:38081436 | DOI:10.1016/j.bbi.2023.12.014 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 11, 2023 Category: Neurology Authors: Susan K Lutgendorf Rachel M Telles Brendan Whitney Premal H Thaker George M Slavich Michael J Goodheart Frank J Penedo Alyssa E Noble Steven W Cole Anil K Sood Benjamin W Corn Source Type: research
Interleukin-10 signaling in somatosensory neurons controls CCL2 release and inflammatory response
In conclusion, we showed that IL-10 binds to its receptor on sensory neurons to downregulate CCL2 and contribute to immunoregulation by reducing the attraction of immune cells by DRG neuron-derived CCL2. This is the first evidence that anti-inflammatory cytokines limit inflammation through direct binding to receptors on sensory neurons. Our data also add to the growing literature that sensory neurons have immunomodulatory functions.PMID:38081433 | DOI:10.1016/j.bbi.2023.12.013 (Source: Brain, Behavior, and Immunity)
Source: Brain, Behavior, and Immunity - December 11, 2023 Category: Neurology Authors: Sabrina de Souza Jes ús Rosario-Claudio Jaewon Sim Kufreobong E Inyang Andrew Dagenais Karli Monahan Beenhwa Lee Hariharan Ramakrishnan Visha Parmar Matan Geron Gr égory Scherrer Joseph K Folger Geoffroy Laumet Source Type: research
