The development of a highly sensitive and quantitative SARS-CoV-2 rapid antigen test applying newly developed monoclonal antibodies to an automated chemiluminescent flow-through membrane immunoassay device
Rapid and accurate diagnosis of individuals with SARS-CoV-2 infection is an effective way to prevent and control the spread of COVID-19. Although the detection of SARS ‐CoV‐2 viral RNA by RT‐qPCR is the gold st... (Source: BMC Immunology)
Source: BMC Immunology - September 26, 2023 Category: Allergy & Immunology Authors: Kengo Nishimura, Hiroaki Kitazawa, Takashi Kawahata, Kosuke Yuhara, Takahiro Masuya, Toshihiro Kuroita, Kentarou Waki, Seiichi Koike, Masaharu Isobe and Nobuyuki Kurosawa Tags: Research Source Type: research
Evaluation of the relationship between serum interleukin-1 β levels and expression of inflammasome-related genes in patients with COVID-19
This study aimed to evaluate the expression of NLR family pyrin domain containing 1 (NLRP1), NLRP3, and Apoptosis-asso... (Source: BMC Immunology)
Source: BMC Immunology - September 18, 2023 Category: Allergy & Immunology Authors: Zahra Bagheri-Hosseinabadi, Ali Shamsizadeh, Fatemeh Bahrehmand and Mitra Abbasifard Tags: Research Source Type: research
Comparison of the effect of autoclaved and non-autoclaved live soil exposure on the mouse immune system
. Lack of exposure to the natural microbial diversity of the environment has been linked to dysregulation of the immune system and numerous noncommunicable diseases, such as allergies and autoimmune disorders.... (Source: BMC Immunology)
Source: BMC Immunology - September 9, 2023 Category: Allergy & Immunology Authors: Laura Kummola, Mart ín I. González-Rodríguez, Pertti Marnila, Noora Nurminen, Tanja Salomaa, Lotta Hiihtola, Iida Mäkelä, Olli H. Laitinen, Heikki Hyöty, Aki Sinkkonen and Ilkka S. Junttila Tags: Research Source Type: research
The effect of serum origin on cytokines induced killer cell expansion and function
Cytokine-induced killer (CIK) cells have shown promising results in adoptive immunotherapy. However, serum may play a determining role in the large-scale expansion of these cells for clinical applications. Acc... (Source: BMC Immunology)
Source: BMC Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Zahra Jabbarpour, Seyed Sajjad Aghayan, Kobra Moradzadeh, Sasan Ghaffari and Naser Ahmadbeigi Tags: Research Source Type: research
Efficacy and safety of immune checkpoint inhibitors in Proficient Mismatch Repair (pMMR)/ Non-Microsatellite Instability-High (non-MSI-H) metastatic colorectal cancer: a study based on 39 cohorts incorporating 1723 patients
This study was designed to investigate the efficacy and safety of immune checkpoint inhibitors (ICIs)-based therapy in proficient mismatch repair (pMMR)/non-microsatellite instability-high (non-MSI-H) metastat... (Source: BMC Immunology)
Source: BMC Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Qing Wu, Ziming Wang, Yang Luo and Xianhe Xie Tags: Research Source Type: research
Higher plasma interleukin − 6 levels are associated with lung cavitation in drug-resistant tuberculosis
This study aimed to determine the relationship between systemic inflammation and lung cavitation in drug-resistant TB ... (Source: BMC Immunology)
Source: BMC Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Thando Glory Maseko, Slindile Ngubane, Marothi Letsoalo, Santhuri Rambaran, Derseree Archary, Natasha Samsunder, Rubeshan Perumal, Surie Chinappa, Nesri Padayatchi, Kogieleum Naidoo and Aida Sivro Tags: Research Source Type: research
HIV specific Th1 responses are altered in Ugandans with HIV and Schistosoma mansoni coinfection
Fishing communities surrounding Lake Victoria in Uganda have HIV prevalence of 28% and incidence rates of 5 per 100 person years. More than 50% of the local fishermen are infected with Schistosoma mansoni (S. man... (Source: BMC Immunology)
Source: BMC Immunology - August 29, 2023 Category: Allergy & Immunology Authors: Andrew Ekii Obuku, Jacqueline Kyosiimire Lugemwa, Andrew Abaasa, Moses Joloba, Song Ding, Justin Pollara, Guido Ferrari, Alexandre Harari, Giuseppe Pantaleo and Pontiano Kaleebu Tags: Research Source Type: research
Higher cytotoxic activities of CD8+ T cells and natural killer cells from peripheral blood of early diagnosed lung cancer patients
Cytotoxic (CD8+) and natural killer (NK) cells play critical roles in anti-tumor immunity. Dysfunction in these cells is considered as one of the extrinsic mechanisms for tumor relapse. (Source: BMC Immunology)
Source: BMC Immunology - August 14, 2023 Category: Allergy & Immunology Authors: Mohamed Labib Salem, Ismail Atia and Nehal M. Elmashad Tags: Research Source Type: research
Platelet-derived extracellular vesicles promote endothelial dysfunction in sepsis by enhancing neutrophil extracellular traps
The role of platelet-derived extracellular vesicles (PEVs) in the development of sepsis was investigated in this study. (Source: BMC Immunology)
Source: BMC Immunology - August 9, 2023 Category: Allergy & Immunology Authors: Meini Jiang, Weidong Wu, Yanmei Xia, Xiuzhe Wang and Jifang Liang Tags: Research Source Type: research
Brachytherapy for targeting the immune system in cervical cancer patients
The objective was to evaluate the impact of brachyth... (Source: BMC Immunology)
Source: BMC Immunology - August 9, 2023 Category: Allergy & Immunology Authors: Isabel Linares, Miguel Ángel Berenguer Frances, Rut Cañas, Dina Najjari, Cristina Gutiérrez, Susanna Marín, Silvia Comas, Ferran Guedea and Monica Pujol Tags: Research Source Type: research
Blood monocyte and dendritic cell profiles among people living with HIV with Mycobacterium tuberculosis co-infection
Understanding the complex interactions of the immune response mediated by Mycobacterium tuberculosis and HIV co-infection is fundamental to disease biomarker discovery, vaccine, and drug development. Using flow c... (Source: BMC Immunology)
Source: BMC Immunology - July 21, 2023 Category: Allergy & Immunology Authors: Santhuri Rambaran, Thando Glory Maseko, Lara Lewis, Razia Hassan-Moosa, Derseree Archary, Sinaye Ngcapu, Nigel Garrett, Lyle R. McKinnon, Nesri Padayatchi, Kogieleum Naidoo and Aida Sivro Tags: Research Source Type: research
A survey of the adaptive immune genes of the polka-dot batfish Ogcocephalus cubifrons
The anglerfish, belonging to the teleost order Lophiiformes, are a diverse and species-rich group of fish that are known to exhibit a number of unique morphological, reproductive and immunological adaptations. Wo... (Source: BMC Immunology)
Source: BMC Immunology - July 21, 2023 Category: Allergy & Immunology Authors: Jeremy B. Swann, Christiane Grammer, Michael Schorpp and Thomas Boehm Tags: Research Source Type: research
Identification of key genes and the pathophysiology associated with allergen-specific immunotherapy for allergic rhinitis
This study is carried out for revealing... (Source: BMC Immunology)
Source: BMC Immunology - July 10, 2023 Category: Allergy & Immunology Authors: Kai Fan, Shican Zhou, Ling Jin, Shiwang Tan, Ju Lai, Zimu Zhang, Jingwen Li, Xiayue Xu, Chunyan Yao, Zhiqiang Yan and Shaoqing Yu Tags: Research Source Type: research
Decreased frequency of Th22 cells and IL-22 cytokine in kidney transplant patients with active cytomegalovirus infection
The immunity of CD4+ T cell subsets against human cytomegalovirus (HCMV) is considerable due to their essential role in controlling the infection in transplant individuals. Previously explained CD4+ subsets such ... (Source: BMC Immunology)
Source: BMC Immunology - July 4, 2023 Category: Allergy & Immunology Authors: Yashgin Hassanzadeh, Ramin Yaghobi, Parviz Pakzad and Bita Geramizadeh Tags: Research Source Type: research
TRPA1 activation and Hsp90 inhibition synergistically downregulate macrophage activation and inflammatory responses in vitro
Transient receptor potential ankyrin 1 (TRPA1) channels are known to be actively involved in various pathophysiological conditions, including neuronal inflammation, neuropathic pain, and various immunological ... (Source: BMC Immunology)
Source: BMC Immunology - June 30, 2023 Category: Allergy & Immunology Authors: Anukrishna Radhakrishnan, Tathagata Mukherjee, Chandan Mahish, P Sanjai Kumar, Chandan Goswami and Subhasis Chattopadhyay Tags: Research Source Type: research
