Ex vivo mRNA expression of toll-like receptors during latent tuberculosis infection
Understanding immune mechanisms, particularly the role of innate immune markers during latent TB infection remains elusive. The main objective of this study was to evaluate mRNA gene expression patterns of tol... (Source: BMC Immunology)
Source: BMC Immunology - January 28, 2021 Category: Allergy & Immunology Authors: Birhan Alemnew, Soren T. Hoff, Tamrat Abebe, Markos Abebe, Abraham Aseffa, Rawleigh Howe and Liya Wassie Tags: Research Source Type: research
Clinical observations of bone marrow transfusion for promoting bone marrow reconstruction after chemotherapy for AIDS-related lymphoma
This study investigates the effect of autologous bone marrow transfusion (BMT) on the reconstruction of both bone marrow and the immune system in patients with AIDS-related lymphoma (ARL). (Source: BMC Immunology)
Source: BMC Immunology - January 28, 2021 Category: Allergy & Immunology Authors: Yixuan Liu, Suhong Xie, Lei Li, Yanhui Si, Weiwei Zhang, Xin Liu, Lin Guo, Baochi Liu and Renquan Lu Tags: Research article Source Type: research
Changes in inflammatory factors in the Brown Norway rat model of food allergy
The role of serum S100A8/A9 in intestinal inflammation has been confirmed, and its role in food allergy is currently being investigated. (Source: BMC Immunology)
Source: BMC Immunology - January 26, 2021 Category: Allergy & Immunology Authors: Qingling Zhu, Junli Wang, Jingqiu Ma, Xiaoyang Sheng and Feng Li Tags: Research article Source Type: research
Neutrophil extracellular traps are present in the airways of ENaC-overexpressing mice with cystic fibrosis-like lung disease
Neutrophils are key components of the exacerbated inflammation and tissue damage in cystic fibrosis (CF) airways. Neutrophil extracellular traps (NETs) trap and kill extracellular pathogens. While NETs are abu... (Source: BMC Immunology)
Source: BMC Immunology - January 21, 2021 Category: Allergy & Immunology Authors: Samantha L. Tucker, Demba Sarr and Bal ázs Rada Tags: Research article Source Type: research
Adaptive immune responses mediated age-related Plasmodium yoelii 17XL and 17XNL infections in 4 and 8-week-old BALB/c mice
It is important to expound the opposite clinical outcomes between children and adulthood for eradicate malaria. There remains unknown about the correlation between adaptive immune response and age-related in m... (Source: BMC Immunology)
Source: BMC Immunology - January 11, 2021 Category: Allergy & Immunology Authors: Qiu-bo Wang, Yun-ting Du, Fei Liu, Xiao-dan Sun, Xun Sun, Guang Chen, Wei Pang and Ya-Ming Cao Tags: Research article Source Type: research
Enhancement of Zika virus infection by antibodies from West Nile virus seropositive individuals with no history of clinical infection
Recent outbreaks of Zika Virus (ZIKV) infection and associated microcephaly has raised multiple scientific questions. The close antigenic relatedness between flaviviruses makes diagnosis of specific infection ... (Source: BMC Immunology)
Source: BMC Immunology - January 9, 2021 Category: Allergy & Immunology Authors: Himanshu Garg, Rose Yeh, Douglas M. Watts, Tugba Mehmetoglu-Gurbuz, Robert Resendes, Bruce Parsons, Fernando Gonzales and Anjali Joshi Tags: Research article Source Type: research
The role of β2 integrin in dendritic cell migration during infection
Dendritic cells (DCs) play a key role in shaping T cell responses. To do this, DCs must be able to migrate to the site of the infection and the lymph nodes to prime T cells and initiate the appropriate immune ... (Source: BMC Immunology)
Source: BMC Immunology - January 6, 2021 Category: Allergy & Immunology Authors: Tarfa Altorki, Werner Muller, Andrew Brass and Sheena Cruickshank Tags: Research Source Type: research
CXCL9 secreted by tumor-associated dendritic cells up-regulates PD-L1 expression in bladder cancer cells by activating the CXCR3 signaling
Tumor-associated dendritic cells (TADCs) can interact with tumor cells to suppress anti-tumor T cell immunity. However, there is no information on whether and how TADCs can modulate programmed death-ligand 1 (... (Source: BMC Immunology)
Source: BMC Immunology - January 6, 2021 Category: Allergy & Immunology Authors: Weigang Xiu and Jingjing Luo Tags: Research article Source Type: research
Utility of basophil activation test for predicting the outcome of wheezing in children: a pilot study
In this study, we analyzed the differences in basophil activation test (BAT) results among children with re... (Source: BMC Immunology)
Source: BMC Immunology - January 6, 2021 Category: Allergy & Immunology Authors: Jingyang Li, Jinhong Wu, Haipei Liu, Li Hua, Quanhua Liu, Dingzhu Fang, Yi Chen, Ruoxu Ji, Jianhua Zhang and Wenwei Zhong Tags: Research Source Type: research
D-mannose ameliorates autoimmune phenotypes in mouse models of lupus
Systemic lupus erythematosus is an autoimmune disease characterized by an overproduction of autoantibodies resulting from dysregulation in multiple immune cell types. D-mannose is a C − 2 epimer of glucose that ex... (Source: BMC Immunology)
Source: BMC Immunology - January 5, 2021 Category: Allergy & Immunology Authors: Haiting Wang, Xiangyu Teng, Georges Abboud, Wei Li, Shuang Ye and Laurence Morel Tags: Research article Source Type: research
Extracellular signal-regulated kinase 1/2 is required for complement component C1q and fibronectin dependent enhancement of Fc γ- receptor mediated phagocytosis in mouse and human cells
C1q is a soluble pattern recognition protein that regulates multiple leukocyte functions, and deficiency in C1q results in autoimmunity. C1q stimulates enhanced phagocytic function through multiple mechanisms ... (Source: BMC Immunology)
Source: BMC Immunology - December 14, 2020 Category: Allergy & Immunology Authors: Emily A. Willmann, Vesna Pandurovic, Anna Jokinen, Danielle Beckley and Suzanne S. Bohlson Tags: Research Source Type: research
Sex and FOXP3 gene rs2232365 polymorphism may be associated with the clinical and pathological aspects of chronic viral diseases
The forkhead box protein 3 (FOXP3) transcription factor is one of the main markers of immunological suppression in different pathological profiles, and the presence of polymorphic variants may alter the gene e... (Source: BMC Immunology)
Source: BMC Immunology - November 19, 2020 Category: Allergy & Immunology Authors: Leonn Mendes Soares Pereira, Max Willy da Silva Madureira, Renata Bezerra Hermes de Castro, Isabella Nogueira Abreu, Simone Regina Souza da Silva Conde, S âmia Demachki, Maisa Silva de Sousa, Maria Alice Freitas Queiroz, Andrea Nazaré M. Rangel da Silva Tags: Research article Source Type: research
The role of CXCR3 and its ligands expression in Brucellar spondylitis
Brucellar spondylitis (BS) is one of the most serious complications of brucellosis. CXCR3 is closely related to the severity of disease infection. This research aimed to study the degree of BS inflammatory dam... (Source: BMC Immunology)
Source: BMC Immunology - November 18, 2020 Category: Allergy & Immunology Authors: Xin Hu, Xiaoqian Shang, Liang Wang, Jiahui Fan, Yue Wang, Jie Lv, Shaxika Nazierhan, Hao Wang, Jing Wang and Xiumin Ma Tags: Research article Source Type: research
Assessing the expression of immunosuppressive cytokines in the newly diagnosed systemic lupus Erythematosus patients: a focus on B cells
The immunosuppressive effects of regulatory B-cells (Bregs) and their immunosuppressive cytokines on immune responses in autoimmune disorders, mainly systemic lupus erythematosus (SLE), have been recently esta... (Source: BMC Immunology)
Source: BMC Immunology - November 16, 2020 Category: Allergy & Immunology Authors: Mitra Abbasifard, Zahra Kamiab, Mohammad Hasani, Amir Rahnama, Pooya Saeed-Askari and Hossein Khorramdelazad Tags: Research article Source Type: research
Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients
Extracellular vesicles (EVs) are nano-sized particles secreted by most cells. EVs carry nucleic acids that hold promise as potential biomarkers in various diseases. Human immunodeficiency virus type 1 (HIV) in... (Source: BMC Immunology)
Source: BMC Immunology - November 11, 2020 Category: Allergy & Immunology Authors: Sukrutha Chettimada, David R. Lorenz, Vikas Misra, Steven M. Wolinsky and Dana Gabuzda Tags: Research article Source Type: research
