Putative novel outer membrane antigens multi-epitope DNA vaccine candidates identified by Immunoinformatic approaches to control Acinetobacter baumannii
Multi-epitope polypeptide vaccines, a fusion protein, often have a string-of-beads system composed of various specific peptide epitopes, potential adjuvants, and linkers. When choosing the sequence of various ... (Source: BMC Immunology)
Source: BMC Immunology - November 18, 2023 Category: Allergy & Immunology Authors: Niloofar Sadat Tabibpour, Abbas Doosti and Ali Sharifzadeh Tags: Research Source Type: research
Long-term humoral and cellular immunity after primary SARS-CoV-2 infection: a 20-month longitudinal study
SARS-CoV-2 remains a world-wide health issue. SARS-CoV-2-specific immunity is induced upon both infection and vaccination. However, defining the long-term immune trajectory, especially after infection, is limi... (Source: BMC Immunology)
Source: BMC Immunology - November 16, 2023 Category: Allergy & Immunology Authors: Astrid Korning Hvidt, Huaijian Guo, Rebecca Andersen, Stine Sofie Frank Lende, Line Khalidan Vibholm, Ole Schmeltz S øgaard, Marianne Hoegsbjerg Schleimann, Victoria Russell, Angela Man-Wei Cheung, Eustache Paramithiotis, Rikke Olesen and Martin Tolstrup Tags: Research Source Type: research
Exploration of biomarkers for systemic lupus erythematosus by machine-learning analysis
In recent years, research on the pathogenesis of systemic lupus erythematosus (SLE) has made great progress. However, the prognosis of the disease remains poor, and high sensitivity and accurate biomarkers are... (Source: BMC Immunology)
Source: BMC Immunology - November 10, 2023 Category: Allergy & Immunology Authors: Xingyun Zhao, Lishuang Duan, Dawei Cui and Jue Xie Tags: Research Source Type: research
Increased infiltration of CD4+ T cell in the complement deficient lymphedema model
Lymphedema is an intractable disease that can be caused by injury to lymphatic vessels, such as by surgical treatments for cancer. It can lead to impaired joint mobility in the extremities and reduced quality ... (Source: BMC Immunology)
Source: BMC Immunology - November 8, 2023 Category: Allergy & Immunology Authors: Toshihiko Nishioka, Kei-ichi Katayama, Shinji Kumegawa, Kyoichi Isono, Takashi Baba, Hiroshi Tsujimoto, Gen Yamada, Norimitsu Inoue and Shinichi Asamura Tags: Research Source Type: research
Tacrolimus reverses pemphigus vulgaris serum-induced depletion of desmoglein in HaCaT cells via inhibition of heat shock protein 27 phosphorylation
Glucocorticoids are the first-line treatment for Pemphigus vulgaris (PV), but its serious side effects can be life-threatening for PV patients. Tacrolimus (FK506) has been reported to have an adjuvant treatmen... (Source: BMC Immunology)
Source: BMC Immunology - November 8, 2023 Category: Allergy & Immunology Authors: Zhimin Xie, Xiangnong Dai, Qingqing Li, Sifan Lin and Xingdong Ye Tags: Research Source Type: research
Vitamin D and biomarkers of inflammation and oxidative stress among pregnant women: a systematic review of observational studies
This systematic review aimed to map the evidence evaluated the relationship between vitamin D and redox and inflammatory status during gestation. (Source: BMC Immunology)
Source: BMC Immunology - October 27, 2023 Category: Allergy & Immunology Authors: Soudabe Motamed, Razieh Anari, Somayeh Motamed and Reza Amani Tags: Research Source Type: research
The upregulation of peripheral CD3-CD56+CD16+ natural killer cells correlates with Th1/Th2 imbalance in asthma patients during acute upper respiratory viral infections
The aim of this study is to clarify the changes of peripheral CD3 −CD56+CD16+ NK cells and their correlation with Th1/Th2 immunity profiles in asthma during the phase of acute upper respiratory viral infections (A... (Source: BMC Immunology)
Source: BMC Immunology - October 21, 2023 Category: Allergy & Immunology Authors: Meixuan Liu, Yunxuan Zhang, Yunqian Hu, Zhongliang Guo and Lin Dong Tags: Research Source Type: research
Humoral immune response and changes in peritoneal cell populations in rats immunized against two Leptospira serovars; serovar patoc and serovar pyrogenes
Leptospirosis is a zoonotic disease caused by Leptospira species. Variations in lipopolysaccharide (LPS) structure in Leptospira are known to be associated with the serovar diversity and antigenicity. Development... (Source: BMC Immunology)
Source: BMC Immunology - October 17, 2023 Category: Allergy & Immunology Authors: Dakshika Gangani, Wathsala Dissanayake, Rajiva de Silva, Kaushalya Anuradha, Lilani Karunanayake, Narmada Fernando, Senaka Rajapakse, Sunil Premawansa and Shiroma Handunnetti Tags: Research Source Type: research
Methionine enkephalin(MENK) upregulated memory T cells in anti-influenza response
Novel prophylactic drugs and vaccination strategies for protection against influenza virus should induce specific effector T-cell immune responses in pulmonary airways and peripheral lymphoid organs. Designing... (Source: BMC Immunology)
Source: BMC Immunology - October 12, 2023 Category: Allergy & Immunology Authors: Jing Tian, Wenrui Fu, Zifeng Xie, Xiaonan Wang, Miao Miao, Fengping Shan and Xiaodong Yu Tags: Research Source Type: research
Transcriptomic analysis identifies CYP27A1 as a diagnostic marker for the prognosis and immunity in lung adenocarcinoma
The association between lipid metabolism disorder and carcinogenesis is well-established, but there is limited research on the connection between lipid metabolism-related genes (LRGs) and lung adenocarcinoma (... (Source: BMC Immunology)
Source: BMC Immunology - October 10, 2023 Category: Allergy & Immunology Authors: Yi Yin, Muqun He, Yunjian Huang and Xianhe Xie Tags: Research Source Type: research
Bcl-3 regulates T cell function through energy metabolism
Bcl-3 is a member of the I κB protein family and an essential modulator of NF-κB activity. It is well established that Bcl-3 is critical for the normal development, survival and differentiation of adaptive immu... (Source: BMC Immunology)
Source: BMC Immunology - October 4, 2023 Category: Allergy & Immunology Authors: Hui Liu, Lin Zeng, Mengmeng Pan, Liwenhui Huang, Hanying Li, Mengxia Liu, Xinqing Niu, Chenguang Zhang and Hui Wang Tags: Research Source Type: research
The digestive system and autoimmunity
Digestive autoimmune conditions are a growing challenge to global health. Risk factors associated with autoimmune digestive diseases are complex, including genetic variation, immunological dysfunction, and var... (Source: BMC Immunology)
Source: BMC Immunology - October 4, 2023 Category: Allergy & Immunology Authors: Lina Sun and Baojun Zhang Tags: Editorial Source Type: research
Function and autophagy of monocyte-derived dendritic cells is affected by hepatitis B virus infection
In this study, we carefully examined the phenotype, f... (Source: BMC Immunology)
Source: BMC Immunology - September 26, 2023 Category: Allergy & Immunology Authors: Hua Xu, Juan Kang, Shan Zhong, Min Chen, Peng Hu, Hong Ren, Zhi Zhou and Yu Lei Tags: Research Source Type: research
Development and validation of a machine learning-based nomogram for predicting HLA-B27 expression
HLA-B27 positivity is normal in patients undergoing rheumatic diseases. The diagnosis of many diseases requires an HLA-B27 examination. (Source: BMC Immunology)
Source: BMC Immunology - September 26, 2023 Category: Allergy & Immunology Authors: Jichong Zhu, Weiming Tan, Xinli Zhan, Qing Lu, Tuo Liang, JieJiang, Hao Li, Chenxing Zhou, Shaofeng Wu, Tianyou Chen, Yuanlin Yao, Shian Liao, Chaojie Yu, Liyi Chen and Chong Liu Tags: Research Source Type: research
Immune cell profiles of idiopathic inflammatory myopathy patients expressed anti-aminoacyl tRNA synthetase or anti-melanoma differentiation-associated gene 5 autoantibodies
Patients with idiopathic inflammatory myopathy (IIM) often express a different type of myositis-specific autoantibodies (MSAs), each associated with different clinical symptoms. Understanding the immunopathoge... (Source: BMC Immunology)
Source: BMC Immunology - September 26, 2023 Category: Allergy & Immunology Authors: Joung-Liang Lan, Shih-Hsin Chang, Gregory J. Tsay, Der-Yuan Chen, Yu-Hua Chao and Ju-Pi Li Tags: Research Source Type: research
