Serum IL-5, POSTN and IL-33 levels in chronic rhinosinusitis with nasal polyposis correlate with clinical severity
Chronic rhinosinusitis (CRS) is a group of heterogeneous diseases characterized by epithelial inflammation and tissue eosinophilic infiltration. IL-5, POSTN, and IL-33 are important factors that act as chemoat... (Source: BMC Immunology)
Source: BMC Immunology - June 25, 2022 Category: Allergy & Immunology Authors: Hanna Zieli ńska-Bliźniewska, Milena Paprocka-Zjawiona, Anna Merecz-Sadowska, Radosław Zajdel, Katarzyna Bliźniewska-Kowalska and Katarzyna Malinowska Tags: Research Source Type: research
The effect of probiotics on immunogenicity of spermatozoa in couples suffering from recurrent spontaneous abortion
Impaired spermatozoa immunogenicity can result in pregnancy complications such as recurrent spontaneous abortion (RSA). Given that spermatozoa contact with microbiota, it is possible that inappropriate microbi... (Source: BMC Immunology)
Source: BMC Immunology - June 20, 2022 Category: Allergy & Immunology Authors: Mitra Rafiee, Nasrin Sereshki, Razieh Alipour, Vahid Ahmadipanah, Davod Pashoutan Sarvar and David Wilkinson Tags: Research Source Type: research
In Vitro Generation of BK polyomavirus-specific T cells for adoptive cell therapy in refractory cystitis hemorrhagic patients after hematopoietic stem cell transplantation
BKPyV associated hemorrhagic cystitis (BKPyV-HC) is a major and prevalent outcome of hematopoietic stem cell transplantation (HSCT) with no standard treatment option. Adoptive T cell therapy (ACT) against tran... (Source: BMC Immunology)
Source: BMC Immunology - June 10, 2022 Category: Allergy & Immunology Authors: Maryam Mohammadi Najafabadi, Masoud Soleimani, Mohammad Ahmadvand, Mina Soufi Zomorrod and Seied Asadollah Mousavi Tags: Research Source Type: research
Comprehensive evaluation of the effects of long-term cryopreservation on peripheral blood mononuclear cells using flow cytometry
Human peripheral blood mononuclear cells (PBMCs) originate from hematopoietic stem cells in the bone marrow, which mainly includes lymphocytes (T cells, B cells, and natural killer cells) and monocytes. Cryopr... (Source: BMC Immunology)
Source: BMC Immunology - June 7, 2022 Category: Allergy & Immunology Authors: Bo Li, Chunmei Yang, Gui Jia, Yansheng Liu, Na Wang, Fangfang Yang, Rui Su, Yulong Shang and Ying Han Tags: Research Source Type: research
Lack of autoantibodies against collagen and related proteins in collagenous colitis
Collagenous colitis (CC) is a common cause of chronic diarrhea and is characterized by a subepithelial thickened collagen layer in the colonic mucosa. (Source: BMC Immunology)
Source: BMC Immunology - June 6, 2022 Category: Allergy & Immunology Authors: Larsson JK, Roth B, Ohlsson B and Sj öberg K Tags: Research Source Type: research
The correlation of EZH2 expression with the progression and prognosis of hepatocellular carcinoma
Enhancer of Zeste homologue 2 (EZH2) is a polycomb group gene and an epigenetic regulator that inhibits transcription, a modification associated with gene silencing. EZH2 plays an essential role in humoral and... (Source: BMC Immunology)
Source: BMC Immunology - June 4, 2022 Category: Allergy & Immunology Authors: Shi-yi Wu, Zhao-yu Xie, Lu-yu Yan, Xiao-fang Liu, Yue Zhang, Da-an Wang, Jie Dong and Hong-tao Sun Tags: Research Source Type: research
Immunological characteristics of MAV/06 strain of varicella-zoster virus vaccine in an animal model
Varicella-zoster virus (VZV) is a pathogen that causes chickenpox and shingles in humans. Different types of the varicella vaccines derived from the Oka and MAV/06 strains are commercially available worldwide.... (Source: BMC Immunology)
Source: BMC Immunology - June 3, 2022 Category: Allergy & Immunology Authors: Duckhyang Shin, Younchul Shin, Eunmi Kim, Hyojung Nam, Haiyan Nan and Jaewoo Lee Tags: Research Source Type: research
Increased serum IL-2, IL-4, IL-5 and IL-12p70 levels in AChR subtype generalized myasthenia gravis
Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular junctions. Cytokines play important roles in facilitating the immune response and augmenting the pathogenic antibody production. The cur... (Source: BMC Immunology)
Source: BMC Immunology - May 27, 2022 Category: Allergy & Immunology Authors: Xiao Huan, Rui Zhao, Jie Song, Huahua Zhong, Manqiqige Su, Chong Yan, Ying Wang, Sheng Chen, Zhirui Zhou, Jiahong Lu, Jianying Xi, Sushan Luo and Chongbo Zhao Tags: Research Source Type: research
Lack of STAT6 enhances murine acute lung injury through NLRP3/p38 MAPK signaling pathway in macrophages
Signal transducer and activator of transcription 6 (STAT6) is an intracelluar transcriotion factor and NLRP3 (Nod-like receptor containing a pyrin domain 3) is a component of NLRP3 inflammasome in pyroptotic c... (Source: BMC Immunology)
Source: BMC Immunology - May 23, 2022 Category: Allergy & Immunology Authors: Lu Hu, Changzhou Shao, Linyue Pan and Zhilong Jiang Tags: Research Source Type: research
Immune correlates of cardiovascular co-morbidity in HIV infected participants from South India
Understanding the immune correlates of cardiovascular disease (CVD) risk in HIV infection is an important area of investigation in the current era of aging with HIV infection. Less is known about CVD risk and ... (Source: BMC Immunology)
Source: BMC Immunology - May 17, 2022 Category: Allergy & Immunology Authors: Bagavathi Kausalya, Shanmugam Saravanan, Suresh Pallikkuth, Rajendra Pahwa, Shelly Rani Saini, Syed Iqbal, Sunil Solomon, Kailapuri G. Murugavel, Selvamuthu Poongulali, Nagalingeswaran Kumarasamy and Savita Pahwa Tags: Research Source Type: research
Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma
Asthma is a common chronic airway disease in the world. The purpose of this study was to explore the expression of IL1-RL1 in sputum and its correlation with Th1 and Th2 cytokines in asthma. (Source: BMC Immunology)
Source: BMC Immunology - May 16, 2022 Category: Allergy & Immunology Authors: Changyi Xu, Lijuan Du, Fengjia Chen, Kun Tang, Lu Tang, Jia Shi, Lisha Xiao, Zhimin Zeng, Yuxia Liang and Yubiao Guo Tags: Research Source Type: research
Influenza virus-like particle vaccine containing both apical membrane antigen 1 and microneme-associated antigen proteins of Plasmodium berghei confers protection in mice
Apical membrane antigen 1 (AMA1) and microneme-associated antigen (MIC) of Plasmodium parasites are important factors involved in host cell invasion. (Source: BMC Immunology)
Source: BMC Immunology - April 25, 2022 Category: Allergy & Immunology Authors: Min-Ju Kim, Ki-Back Chu, Hae-Ji Kang, Keon-Woong Yoon, Dong-Hun Lee, Su-Hwa Lee, Eun-Kyung Moon and Fu-Shi Quan Tags: Research Source Type: research
High resolution HLA-DRB1 analysis and shared molecular amino acid signature of DR β1 molecules in Occult hepatitis B infection
To investigate the association of human leukocyte antigen (HLA)-DRB1 alleles and the variations of polymorphic amino acid changes in DR β1 chain in Shaanxi Han population with Occult hepatitis B infection (OBI). (Source: BMC Immunology)
Source: BMC Immunology - April 25, 2022 Category: Allergy & Immunology Authors: Tianju Wang, Chunmei Shen, Hengxin Li, Liping Chen, Sheng Liu and Jun Qi Tags: Article Source Type: research
Macrophage-targeted anti-CCL2 immunotherapy enhances tumor sensitivity to 5-fluorouracil in a Balb/c-CT26 murine colon carcinoma model measured using diffuse reflectance spectroscopy
Immunotherapy in colorectal cancer (CRC) regulates specific immune checkpoints and, when used in combination with chemotherapy, can improve patient prognosis. One specific immune checkpoint is the recruitment ... (Source: BMC Immunology)
Source: BMC Immunology - April 23, 2022 Category: Allergy & Immunology Authors: Shelby N. Bess, Gage J. Greening, Narasimhan Rajaram and Timothy J. Muldoon Tags: Research Source Type: research
Three important short-chain fatty acids (SCFAs) attenuate the inflammatory response induced by 5-FU and maintain the integrity of intestinal mucosal tight junction
5-Fluorouracil (5-FU) is a used chemotherapy drug for cancer, and its main side effect is intestinal mucositis which causes chemotherapy to fail. It was known that short-chain fatty acids (SCFAs) can inhibit i... (Source: BMC Immunology)
Source: BMC Immunology - April 21, 2022 Category: Allergy & Immunology Authors: Xi Yue, Sun Wen, Ding Long-kun, Yan Man, Sun Chang, Zhang Min, Li Shuang-yu, Qian Xin, Ma Jie and Wu Liang Tags: Research Source Type: research
