Immune correlates of cardiovascular co-morbidity in HIV infected participants from South India
Understanding the immune correlates of cardiovascular disease (CVD) risk in HIV infection is an important area of investigation in the current era of aging with HIV infection. Less is known about CVD risk and ... (Source: BMC Immunology)
Source: BMC Immunology - May 17, 2022 Category: Allergy & Immunology Authors: Bagavathi Kausalya, Shanmugam Saravanan, Suresh Pallikkuth, Rajendra Pahwa, Shelly Rani Saini, Syed Iqbal, Sunil Solomon, Kailapuri G. Murugavel, Selvamuthu Poongulali, Nagalingeswaran Kumarasamy and Savita Pahwa Tags: Research Source Type: research

Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma
Asthma is a common chronic airway disease in the world. The purpose of this study was to explore the expression of IL1-RL1 in sputum and its correlation with Th1 and Th2 cytokines in asthma. (Source: BMC Immunology)
Source: BMC Immunology - May 16, 2022 Category: Allergy & Immunology Authors: Changyi Xu, Lijuan Du, Fengjia Chen, Kun Tang, Lu Tang, Jia Shi, Lisha Xiao, Zhimin Zeng, Yuxia Liang and Yubiao Guo Tags: Research Source Type: research

Influenza virus-like particle vaccine containing both apical membrane antigen 1 and microneme-associated antigen proteins of Plasmodium berghei confers protection in mice
Apical membrane antigen 1 (AMA1) and microneme-associated antigen (MIC) of Plasmodium parasites are important factors involved in host cell invasion. (Source: BMC Immunology)
Source: BMC Immunology - April 25, 2022 Category: Allergy & Immunology Authors: Min-Ju Kim, Ki-Back Chu, Hae-Ji Kang, Keon-Woong Yoon, Dong-Hun Lee, Su-Hwa Lee, Eun-Kyung Moon and Fu-Shi Quan Tags: Research Source Type: research

High resolution HLA-DRB1 analysis and shared molecular amino acid signature of DR β1 molecules in Occult hepatitis B infection
To investigate the association of human leukocyte antigen (HLA)-DRB1 alleles and the variations of polymorphic amino acid changes in DR β1 chain in Shaanxi Han population with Occult hepatitis B infection (OBI). (Source: BMC Immunology)
Source: BMC Immunology - April 25, 2022 Category: Allergy & Immunology Authors: Tianju Wang, Chunmei Shen, Hengxin Li, Liping Chen, Sheng Liu and Jun Qi Tags: Article Source Type: research

Macrophage-targeted anti-CCL2 immunotherapy enhances tumor sensitivity to 5-fluorouracil in a Balb/c-CT26 murine colon carcinoma model measured using diffuse reflectance spectroscopy
Immunotherapy in colorectal cancer (CRC) regulates specific immune checkpoints and, when used in combination with chemotherapy, can improve patient prognosis. One specific immune checkpoint is the recruitment ... (Source: BMC Immunology)
Source: BMC Immunology - April 23, 2022 Category: Allergy & Immunology Authors: Shelby N. Bess, Gage J. Greening, Narasimhan Rajaram and Timothy J. Muldoon Tags: Research Source Type: research

Three important short-chain fatty acids (SCFAs) attenuate the inflammatory response induced by 5-FU and maintain the integrity of intestinal mucosal tight junction
5-Fluorouracil (5-FU) is a used chemotherapy drug for cancer, and its main side effect is intestinal mucositis which causes chemotherapy to fail. It was known that short-chain fatty acids (SCFAs) can inhibit i... (Source: BMC Immunology)
Source: BMC Immunology - April 21, 2022 Category: Allergy & Immunology Authors: Xi Yue, Sun Wen, Ding Long-kun, Yan Man, Sun Chang, Zhang Min, Li Shuang-yu, Qian Xin, Ma Jie and Wu Liang Tags: Research Source Type: research

Exhausted phenotype of circulating CD8+ T cell subsets in hepatitis B virus carriers
Chronic hepatitis B virus (HBV) infection is characterized by the presence of dysfunctional exhausted CD8+ T cells that hamper viral control. We investigated the phenotypic heterogeneity of exhausted CD8+ T cells... (Source: BMC Immunology)
Source: BMC Immunology - April 20, 2022 Category: Allergy & Immunology Authors: Daixi Jiang, Can Chen, Danying Yan, Xiaobao Zhang, Xiaoxiao Liu, Dong Yan, Dawei Cui and Shigui Yang Tags: Research Source Type: research

Docosahexaenoic acid supplementation represses the early immune response against murine cytomegalovirus but enhances NK cell effector function
Docosahexaenoic acid (DHA) supplementation is beneficial for several chronic diseases; however, its effect on immune regulation is still debated. Given the prevalence of cytomegalovirus (CMV) infection and bec... (Source: BMC Immunology)
Source: BMC Immunology - April 19, 2022 Category: Allergy & Immunology Authors: Shuting Wu, Shanshan Wang, Lili Wang, Hongyan Peng, Shuju Zhang, Qinglan Yang, Minghui Huang, Yana Li, Shuzhen Guan, Wenjuan Jiang, Zhaohui Zhang, Qinghua Bi, Liping Li, Yuan Gao, Peiwen Xiong, Zhaoyang Zhong & hellip; Tags: Research Source Type: research

ThPOK inhibits the immune escape of gastric cancer cells by inducing STPG1 to inactivate the ERK pathway
This study aimed to inve... (Source: BMC Immunology)
Source: BMC Immunology - April 4, 2022 Category: Allergy & Immunology Authors: Ying Chen, Lili Jiang, Lingli Xia, Gang Zhang and Lan Chen Tags: Research Source Type: research

A longitudinal analysis of immune escapes from HLA-B*13-restricted T-cell responses at early stage of CRF01_AE subtype HIV-1 infection and implications for vaccine design
Identifying immunogens which can elicit effective T cell responses against human immunodeficiency virus type 1 (HIV-1) is important for developing a T-cell based vaccine. It has been reported that human leukoc... (Source: BMC Immunology)
Source: BMC Immunology - April 2, 2022 Category: Allergy & Immunology Authors: Hui Zhang, Chuan He, Fanming Jiang, Shuang Cao, Bin Zhao, Haibo Ding, Tao Dong, Xiaoxu Han and Hong Shang Tags: Research Source Type: research

Oxidative stress-related circulating miRNA-27a is a potential biomarker for diagnosis and prognosis in patients with sepsis
Oxidative stress plays a critical role on the processes of sepsis, and several microRNAs have been identified that may regulate the occurrence of oxidative stress. However, the relation between oxidative stres... (Source: BMC Immunology)
Source: BMC Immunology - March 25, 2022 Category: Allergy & Immunology Authors: Yingwei Ou, Rongcheng An, Haochu Wang, Lue Chen, Yong Shen, Wenwei Cai and Wei Zhu Tags: Research Source Type: research

CD4, CD8 and natural killer cells are depressed in patients with alopecia areata: their association with disease activity
Alopecia areata (AA) is a common inflammatory disorder targeting the hair follicles leading to non-scaring hair loss. The pathogenesis of AA is still unclear, despite the accumulating evidence of the immune-me... (Source: BMC Immunology)
Source: BMC Immunology - March 17, 2022 Category: Allergy & Immunology Authors: Abdel-Khalek Younes, Refaat Hammad, Mona Othman and Ali Sobhy Tags: Research Source Type: research

Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1
Human immunodeficiency virus type 1 (HIV-1) causes impairment of T and B cell responses, which begins during the acute phase of infection and is not completely restored by antiretroviral treatment. Regulatory ... (Source: BMC Immunology)
Source: BMC Immunology - March 14, 2022 Category: Allergy & Immunology Authors: Raquel Matavele Chissumba, Cacildo Magul, Rosa Macamo, V ânia Monteiro, Maria Enosse, Ivalda Macicame, Victória Cumbane, Nilesh Bhatt, Edna Viegas, Michelle Imbach, Leigh Anne Eller, Christina S. Polyak and Luc Kestens Tags: Research Source Type: research

ERAP1 is a critical regulator of inflammasome-mediated proinflammatory and ER stress responses
In addition to its role in antigen presentation, recent reports establish a new role for endoplasmic reticulum aminopeptidase 1 (ERAP1) in innate immunity; however, the mechanisms underlying these functions ar... (Source: BMC Immunology)
Source: BMC Immunology - March 4, 2022 Category: Allergy & Immunology Authors: Maja K. Blake, Patrick O ’Connell, Yuliya Pepelyayeva, Sarah Godbehere, Yasser A. Aldhamen and Andrea Amalfitano Tags: Research Source Type: research

The influences of perfluoroalkyl substances on the rheumatoid arthritis clinic
The effect of environmental factors on genetically susceptible individuals is a basic link in the pathogenesis of rheumatoid arthritis. Perfluoroalkyl substances (PFASs) are a class of synthetic organic fluori... (Source: BMC Immunology)
Source: BMC Immunology - March 4, 2022 Category: Allergy & Immunology Authors: Yun Zhao, Hangbiao Jin, Jianli Qu, Sunzhao Zhang, Shilei Hu, Jing Xue and Meirong Zhao Tags: Research Source Type: research