The effect of tuberculosis on immune reconstitution among HIV patients on highly active antiretroviral therapy in Adigrat general hospital, eastern Tigrai, Ethiopia; 2019: a retrospective follow up study
Ethiopia initiated antiretroviral therapy early in 2005. Managing and detecting antiretroviral treatment response is important to monitor the effectiveness of medication and possible drug switching for low imm... (Source: BMC Immunology)
Source: BMC Immunology - December 5, 2019 Category: Allergy & Immunology Authors: Hadush Negash, Haftom Legese, Mebrahtu Tefera, Fitsum Mardu, Kebede Tesfay, Senait Gebresilasie, Berhane Fseha, Tsega Kahsay, Aderajew Gebrewahd and Brhane Berhe Tags: Research article Source Type: research

Using the K/BxN mouse model of endogenous, chronic, rheumatoid arthritis for the evaluation of potential immunoglobulin-based therapeutic agents, including IVIg and Fc- μTP-L309C, a recombinant IgG1 Fc hexamer
High-dose intravenous immunoglobulin (IVIg), and more recently, subcutaneously-delivered Ig (SCIg), are used to treat a variety of autoimmune diseases; however, there are challenges associated with product pro... (Source: BMC Immunology)
Source: BMC Immunology - December 4, 2019 Category: Allergy & Immunology Authors: Bonnie J. B. Lewis, Jade Ville, Megan Blacquiere, Selena Cen, Rolf Spirig, Adrian W. Zuercher, Fabian K äsermann and Donald R. Branch Tags: Research article Source Type: research

Immunogenicity of Del19 EGFR mutations in Chinese patients affected by lung adenocarcinoma
Mutant peptides presented by cancer cells are superior vaccine candidates than self peptides. The efficacy of mutant K-Ras, P53 and EGFR (Epidermal Growth Factor Receptor) peptides have been tested as cancer v... (Source: BMC Immunology)
Source: BMC Immunology - November 13, 2019 Category: Allergy & Immunology Authors: Deng Pan, Dapeng Zhou, Weijing Cai, Weibo Wu, Wen Ling Tan, Caicun Zhou and Yanyan Lou Tags: Research article Source Type: research

Subsets of mononuclear phagocytes are enriched in the inflamed colons of patients with IBD
Myeloid cells, especially mononuclear phagocytes, which include monocytes, macrophages and dendritic cells (DC), play vital roles in innate immunity, and in the initiation and maintenance of adaptive immunity.... (Source: BMC Immunology)
Source: BMC Immunology - November 12, 2019 Category: Allergy & Immunology Authors: Hong Liu, Suryasarathi Dasgupta, Yu Fu, Brandi Bailey, Christian Roy, Eric Lightcap and Benjamin Faustin Tags: Research article Source Type: research

The effect of pneumococcal immunization on total and antigen-specific B cells in patients with severe chronic kidney disease
While the 23-valent pneumococcal polysaccharide vaccine (PPV23) is routinely used in Canada and some other countries to prevent pneumococcal infection in adults with chronic kidney disease (CKD), patients deve... (Source: BMC Immunology)
Source: BMC Immunology - November 12, 2019 Category: Allergy & Immunology Authors: Gabrielle Nicole Gaultier, William McCready and Marina Ulanova Tags: Research article Source Type: research