Fasciola gigantica vaccine construct: an in silico approach towards identification and design of a multi-epitope subunit vaccine using calcium binding EF-hand proteins
Continuous attempts have been made to pinpoint candidate vaccine molecules and evaluate their effectiveness in order to commercialise such vaccines for the treatment of tropical fascioliasis in livestock. The ... (Source: BMC Immunology)
Source: BMC Immunology - January 5, 2023 Category: Allergy & Immunology Authors: Kanhu Charan Das, Ruchishree Konhar and Devendra Kumar Biswal Tags: Research Source Type: research
The exhaustion of lymphocytes is the main factor that decreases the sensitivity of QFT-GIT detection in silicosis
This study will analyze the r... (Source: BMC Immunology)
Source: BMC Immunology - December 31, 2022 Category: Allergy & Immunology Authors: Xin Yu, Li-Na Huang, Jun-Chi Xu, Yi-Yan Song, Hui Chen, Cui-Lin Shi, Pei-Jun Tang, Tao Tao and Ye-Han Zhu Tags: Research Source Type: research
Pathogen exposure influences immune parameters around weaning in pigs reared in commercial farms
Multiple antigenic stimulations are crucial to immune system training during early post-natal life. These stimulations can be either due to commensals, which accounts for the acquisition and maintenance of tol... (Source: BMC Immunology)
Source: BMC Immunology - December 10, 2022 Category: Allergy & Immunology Authors: Julie Herv é, Karine Haurogné, Arnaud Buchet, Elodie Bacou, Grégoire Mignot, Marie Allard, Mily Leblanc-Maridor, Solenn Gavaud, Anne Lehébel, Elena Terenina, Pierre Mormède, Elodie Merlot, Catherine Belloc, Jean-Marie Bach and Blandine Lieubeau Tags: Research Source Type: research
Combined application of dinitrofluorobenzene and ovalbumin induced AD-like dermatitis with an increase in helper T-cell cytokines and a prolonged Th2 response
The progression of acute-to-chronic atopic dermatitis is accompanied by multiple helper T-cell cytokine responses, but the mechanisms and relative importance of these changes remain unclear. There is no animal... (Source: BMC Immunology)
Source: BMC Immunology - December 7, 2022 Category: Allergy & Immunology Authors: Pengju Jiang, Yaguang Wu, Lu Liu, Lian Zhang and Zhiqiang Song Tags: Research Source Type: research
DDX1 is a prognostic biomarker and correlates with immune infiltrations in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the leading lethal malignant tumors worldwide. DEAD-box (DDX) family helicases are implicated in numerous human cancers. However, the role of DDX1 in HCC has not yet be... (Source: BMC Immunology)
Source: BMC Immunology - November 30, 2022 Category: Allergy & Immunology Authors: Mengping Yuan, Jinyong Xu, Shuguang Cao and Shuangshuang Sun Tags: Research Source Type: research
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor
This study focused on the role of propofol in the balance of Th17/Treg in elderly patients with l... (Source: BMC Immunology)
Source: BMC Immunology - November 25, 2022 Category: Allergy & Immunology Authors: Can Cui, Dengwen Zhang, Ke Sun, Yi Zhu, Jindong Xu, Yin Kang, Guangyan Zhang, Yujin Cai, Songsong Mao, Ruichun Long, Jue Ma, Song Dong and Yi Sun Tags: Research Source Type: research
A longitudinal study of humoral immune responses induced by a 3-dose inactivated COVID-19 vaccine in an observational, prospective cohort
To determine the dynamic SARS-CoV-2 specific antibody levels induced by 3 doses of an inactivated COVID-19 vaccine, CoronaVac. An observational, prospective cohort study was performed with 93 healthy healthcar... (Source: BMC Immunology)
Source: BMC Immunology - November 16, 2022 Category: Allergy & Immunology Authors: Yue Tao, Mengyin Ma, Fenghua Hu, Ming Li, Yu Geng, Yawen Wan, Minxin Mao, Lin Chen, Ya Shen, Liguo Zhu, Han Shen and Yuxin Chen Tags: Research Source Type: research
CD206+CD68+ mono-macrophages and serum soluble CD206 level are increased in antineutrophil cytoplasmic antibodies associated glomerulonephritis
In this study, we aim to investi... (Source: BMC Immunology)
Source: BMC Immunology - November 15, 2022 Category: Allergy & Immunology Authors: Xiao-Ning An, Zhao-Nan Wei, Yin-Yin Xie, Jing Xu, Yan Shen, Li-Yan Ni, Hao Shi, Ping-Yan Shen, Wen Zhang and Yong-Xi Chen Tags: Research Source Type: research
Regulatory and effector T cell subsets in tumor-draining lymph nodes of patients with squamous cell carcinoma of head and neck
In this study, we investigated the cytokine and regulatory profiles... (Source: BMC Immunology)
Source: BMC Immunology - November 15, 2022 Category: Allergy & Immunology Authors: Marzieh Norouzian, Fereshteh Mehdipour, Mohammad Javad Ashraf, Bijan Khademi and Abbas Ghaderi Tags: Research Source Type: research
CD19+CD24hiCD38hi regulatory B cells deficiency revealed severity and poor prognosis in patients with sepsis
Sepsis still remains a major challenge in intensive care medicine with unacceptably high mortality among patients with septic shock. Due to current limitations of human CD19+CD24hiCD38hi Breg cells (Bregs) studie... (Source: BMC Immunology)
Source: BMC Immunology - November 10, 2022 Category: Allergy & Immunology Authors: Chunmei Wang, Huihui Xu, Rui Gao, Fengying Leng, Fangjie Huo, Yinzhen Li, Siting Liu, Mingzheng Xu and Jianwen Bai Tags: Research Source Type: research
Immunomodulatory effects of β-defensin 2 on macrophages induced immuno-upregulation and their antitumor function in breast cancer
Macrophages are mononuclear CD34+ antigen-presenting cells of defense mechanism and play dual roles in tumor burden. The immunomodulatory and their antitumor function of β-defensin 2 is still unclear, despite the... (Source: BMC Immunology)
Source: BMC Immunology - November 2, 2022 Category: Allergy & Immunology Authors: Sonam Agarwal, Anita Chauhan, Khushwant Singh, Kunal Kumar, Rupinder Kaur, Marilyn Masih and Pramod Kumar Gautam Tags: Research Source Type: research
Sex differences exist in adult heart group 2 innate lymphoid cells
Group 2 innate lymphoid cells (ILC2s) are the most dominant ILCs in heart tissue, and sex-related differences exist in mouse lung ILC2 phenotypes and functions; however, it is still unclear whether there are s... (Source: BMC Immunology)
Source: BMC Immunology - October 31, 2022 Category: Allergy & Immunology Authors: Hongyan Peng, Shuting Wu, Shanshan Wang, Qinglan Yang, Lili Wang, Shuju Zhang, Minghui Huang, Yana Li, Peiwen Xiong, Zhaohui Zhang, Yue Cai, Liping Li, Youcai Deng and Yafei Deng Tags: Research Source Type: research
Restoration of dendritic cell homeostasis and Type I/Type III interferon levels in convalescent COVID-19 individuals
Plasmacytoid and myeloid dendritic cells play a vital role in the protection against viral infections. In COVID-19, there is an impairment of dendritic cell (DC) function and interferon secretion which has bee... (Source: BMC Immunology)
Source: BMC Immunology - October 26, 2022 Category: Allergy & Immunology Authors: Anuradha Rajamanickam, Nathella Pavan Kumar, Arul Nancy Pandiaraj, Nandhini Selvaraj, Saravanan Munisankar, Rachel Mariam Renji, Vijayalakshmi Venkatramani, Manoj Murhekar, Jeromie Wesley Vivian Thangaraj, Muthusamy Santhosh Kumar, Chethrapilly Purushotha Tags: Research Source Type: research
Modulation of immunological responses by aqueous extract of Datura stramonium L. seeds on cyclophosphamide-induced immunosuppression in Wistar rats
This study investigated the immunomodula... (Source: BMC Immunology)
Source: BMC Immunology - October 19, 2022 Category: Allergy & Immunology Authors: Parker Elijah Joshua, Junaidu Yahaya, Daniel Emmanuel Ekpo, Joyce Oloaigbe Ogidigo, Arome Solomon Odiba, Rita Onyekachukwu Asomadu, Samson Ayodeji Oka and Olasupo Stephen Adeniyi Tags: Research Source Type: research
Low-dose interleukin-2 can improve salivary secretion but not lymphocyte infiltration of salivary glands in a murine model of Sj ögren’s syndrome
Effects of low-dose interleukin-2 (IL-2) on the exocrine glandular glands of Sj ögren’s syndrome are unknown. The aim of this study was to investigate the effects of low-dose IL-2 on salivary gland structure an... (Source: BMC Immunology)
Source: BMC Immunology - October 16, 2022 Category: Allergy & Immunology Authors: Junsong Wen, Fenglin Zhu, Xi Yu, Hualing Xie and Chengyin Li Tags: Research Source Type: research
