Impact of preoperative [18F]FDG PET/CT vs. contrast-enhanced CT in the staging and survival of patients with clinical stage I and II non-small cell lung cancer: a 10-year follow-up study
ConclusionAddition of preoperative [18F]FDG PET/CT was associated with superior DFS and OS in resectable cI –II NSCLC, which may result from accurate staging and stage-appropriate therapy. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - March 1, 2024 Category: Nuclear Medicine Source Type: research

The value of 18F-FDG PET/CT in Langerhans cell histiocytosis
Conclusions18F-FDG PET/CT is an effective way to diagnose and evaluate LCH. PET metabolic parameters were associated with laboratory inflammatory markers, suggesting that 18F-FDG PET/CT may be helpful in evaluating disease activity of LCH. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - March 1, 2024 Category: Nuclear Medicine Source Type: research

Nuclear medicine practice in Japan: a report of the ninth nationwide survey in 2022
AbstractSubcommittee on Survey of Nuclear Medicine Practice in Japan has performed a nationwide survey of nuclear medicine practice every 5  years since 1982 to survey contemporary nuclear medicine practice and its changes over the years. The subcommittee sent questionnaires, including the number and category of examinations as well as the kind of the radiopharmaceuticals during the 30 days of June 2022 to all nuclear medicine institu tes in Japan. The total numbers of them for the year 2022 were estimated depends on the 1-month data. A total of 1095 institutes responded to the survey, including 364 positron emission tom...
Source: Annals of Nuclear Medicine - February 29, 2024 Category: Nuclear Medicine Source Type: research

Properties of [18F]FAPI monitoring of acute radiation pneumonia versus [18F]FDG in mouse models
ConclusionsThe background uptake of [18F]FAPI is negligible. Moreover, the uptake of [18F]FAPI may not be affected by acute radiation pneumonitis compared to [18F]FDG, which may be used to more accurately evaluate early radiotherapy response of lung cancer with acute radiation pneumonia. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - February 26, 2024 Category: Nuclear Medicine Source Type: research

Simultaneous evaluation of brain metastasis and thoracic cancer using semiconductor 11C-methionine PET/CT imaging
ConclusionIn digital MET-PET/CT imaging, TNR was a more useful parameter to differentiate LR from RN than SUVmax, and the cutoff value was higher than those with conventional PET systems. Additional whole-body scans could detect extracranial recurrence and would be especially useful for advanced thoracic cancer patients who underwent non-surgical treatment. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - February 22, 2024 Category: Nuclear Medicine Source Type: research

A fully automatic deep learning-based method for segmenting regions of interest and predicting renal function in pediatric dynamic renal scintigraphy
ConclusionWe propose a reliable and stable DL model that can fully automatically segment ROIs and accurately predict renal function in pediatric99mTc-EC DRS. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - February 20, 2024 Category: Nuclear Medicine Source Type: research

Effect of Cyclosporin H on ischemic injury and neutrophil infiltration in cerebral infarct model of rats via PET imaging
ConclusionPotent FPR antagonist CsH is promisingly beneficial in attenuating neuroinflammation and improving neurobehavioral function against cerebral infarction. Therefore, FPR may become a novel target for regulating neuroinflammation and improving prognosis for ischemic cerebrovascular disorders. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - February 15, 2024 Category: Nuclear Medicine Source Type: research

Methyl-11C-L-methionine positron emission tomography for radiotherapy planning for recurrent malignant glioma
ConclusionsThe region of11C-MET accumulation is not necessarily consistent with and larger than the Gd-enhanced region. A change of the tumor boundary using11C-MET PET can cause significant changes in doses to the brain and the CTV. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - February 14, 2024 Category: Nuclear Medicine Source Type: research

Radiolabeled florescent-magnetic graphene oxide nanosheets: probing the biodistribution of a potential PET-MRI hybrid imaging agent for detection of fibrosarcoma tumor
ConclusionMagnetic (Fe3O4) and fluorescent components (CdTe QDs) along with a positron-emitting radionuclide will help to design a multimodal imaging system (PET/MRI/OI) which will offer the advantages of combined imaging techniques and further possible used in localized radionuclide therapy. Overall, [68Ga] Ga-GO@Fe3O4-cys-CdTe QDs nanocomposite shows great promise as a radiolabeled imaging agent owing to high accumulation in tumor region. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - February 12, 2024 Category: Nuclear Medicine Source Type: research