99mTc-Rituximab sentinel lymph node mapping and biopsy, the effective technique avoids axillary dissection and predicts prognosis in 533 cutaneous melanoma
ConclusionThe novel radiotracer99mTc-rituximab could identify SLNs specifically in SLN lymphoscintigraphy and SLNB in CMM patients, and the pathology obtained from SLNB rather than from RLND better indicated the staging and long-term prognosis. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - December 31, 2022 Category: Nuclear Medicine Source Type: research
Brain imaging of sequential acquisition using a flexible PET scanner and 3-T MRI: quantitative and qualitative assessment
ConclusionsfxPET could successfully determine physiological [18F]FDG uptake; however, improved image clarity is desirable. In this study, fxPET/MRI at 3-T was feasible for brain imaging. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - December 31, 2022 Category: Nuclear Medicine Source Type: research
Incidence of renal scarring on technetium-99 m dimercaptosuccinic acid renal scintigraphy after acute pyelonephritis, acute focal bacterial nephritis, and renal abscess
ConclusionOur results showed that pediatric patients with renal scarring on chronic-phase DMSA renal scintigraphy tended to have a more severe renal infection. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - December 21, 2022 Category: Nuclear Medicine Source Type: research
Invasive mucinous adenocarcinoma of the lung: clinicopathological features, 18F-FDG PET/CT findings, and survival outcomes
Conclusion18F-FDG PET/CT combined with clinicopathological characteristics can aid the diagnosis and prognostic evaluation of lung IMA, which could provide guidance for the appropriate management of such patients. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - December 20, 2022 Category: Nuclear Medicine Source Type: research
Prognostic value of semi-quantitative parameters of 18F-FDG PET/CT in newly diagnosed multiple myeloma patients
ConclusionaMTV can predict PFS and OS of NDMM patients better than other parameters. NS which combined with aMTV can predict OS of NDMM patients better and can provide an accurate and simple method for risk stratification of NDMM patients. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - December 17, 2022 Category: Nuclear Medicine Source Type: research
Melissa Officinalis L. aqueous extract pretreatment decreases methotrexate-induced hepatotoxicity at lower dose and increases 99mTc-phytate liver uptake, as a probe of liver toxicity assessment, in rats
ConclusionIn conclusion, we highlighted the liver uptake of99mTc-phytate as a valuable method for assessment of liver toxicity and addressed thatM. officinalis pretreatment (100 mg/kg for 14 days) ameliorates the MTX-associated hepatotoxicity in rats; however,M. officinalis itself induces liver toxicity at higher doses.Graphical abstract (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - December 5, 2022 Category: Nuclear Medicine Source Type: research
The evaluation of DLCO changes in patients with relatively higher lung shunt fractions receiving TARE
ConclusionOur study showed that a significant reduction in DLCO after TARE may occur in patients with relatively higher lung shunt fractions. Further studies with larger sample sizes are needed to better investigate the changes in DLCO in patients with high lung shunt fractions. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - November 27, 2022 Category: Nuclear Medicine Source Type: research
Glucose metabolic heterogeneity correlates with pathological features and improves survival stratification of resectable lung adenocarcinoma
ConclusionThe glycolytic heterogeneity portrayed by entropy is associated with aggressive histopathological characteristics. The proposed entropy-based models may provide more sophisticated survival stratification in addition to histopathology and may enable personalized treatment strategies for resectable lung cancer. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - November 27, 2022 Category: Nuclear Medicine Source Type: research
Reproducibility assessment of uptake on dedicated breast PET for noise discrimination
ConclusionsOur results demonstrated that reproducibility assessment helped reduce false-positive findings caused by noise on dbPET without lowering the sensitivity for malignancy. While subjective visual assessment was also efficient in increasing PPV, it occasionally missed malignant uptake. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - November 25, 2022 Category: Nuclear Medicine Source Type: research
Dosimetry and efficacy of a tau PET tracer [18F]MK-6240 in Japanese healthy elderly and patients with Alzheimer ’s disease
ConclusionThe findings supported safety and efficacy of [18F]MK-6240 as a tau PET tracer for Japanese populations. Even though the number of subjects was limited, the radiation dosimetry profiles, pharmacokinetics, and biodistribution of [18F]MK-6240 were consistent with those for non-Japanese populations.Trial registrationJapan Pharmaceutical Information Center ID, JapicCTI-194972. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - November 21, 2022 Category: Nuclear Medicine Source Type: research
Evaluation of standardized uptake value on 131I-6 β-iodomethyl-19-norcholesterol scintigraphy for diagnosis of primary aldosteronism and correspondence with adrenal venous sampling
ConclusionIn this study, SUV on NP-59 SPECT helped in the diagnosis of PA and was consistent with the results of AVS in nearly all cases. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - November 15, 2022 Category: Nuclear Medicine Source Type: research
Prognostic value of textural features obtained from F-fluorodeoxyglucose (F-18 FDG) positron emission tomography/computed tomography (PET/CT) in patients with locally advanced cervical cancer undergoing concurrent chemoradiotherapy
ConclusionOur results demonstrated that high GLNU from GLRLM on pretreatment F-18 FDG PET/CT images, were significant prognostic factors for recurrence and death in patients with LACC receiving CCRT. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - November 12, 2022 Category: Nuclear Medicine Source Type: research
Comparison of 1-h with 3-h planar 99mTc-pyrophosphate scintigraphy in patients with suspected transthyretin cardiac amyloidosis using SPECT as a reference standard
ConclusionsIn the assessment of ATTR-CA using PYP imaging, visual scores on 3-h anterior planar images for identifying positive PYP SPECT had lower sensitivity and higher specificity in comparison with those on 1-h anterior planar images. The diagnostic value of the visual scores on 1-h and 3-h anterior planar images was not improved by adding the H/CL ratio. Blood pool activity of PYP was not significantly associated with renal dysfunction. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - November 10, 2022 Category: Nuclear Medicine Source Type: research
Comparative evaluation of radionuclide therapy using 90Y and 177Lu
ConclusionsTo accomplish a maximum therapeutic effect, selecting90Y or177Lu, to depend on the growth rate of individual cancer, would be helpful. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - November 9, 2022 Category: Nuclear Medicine Source Type: research
Dosimetry estimation and preliminary clinical application of [99mTc]Tc-HYNIC-PSMA-XL-2 in prostate cancer
Conclusion[99mTc]Tc-HYNIC-PSMA-XL-2 is a safe SPECT/CT tracer, which can detect prostate malignant lesions without interference from the bladder. In addition, the malignant lesions of the lymph node and bone of PCa patients also can be detected efficiently. (Source: Annals of Nuclear Medicine)
Source: Annals of Nuclear Medicine - November 8, 2022 Category: Nuclear Medicine Source Type: research
