Effect of Ascending Aortic Curvature on Flow in the Sinus and Neo-sinus Following TAVR: A Patient-Specific Study
Ann Biomed Eng. 2023 Nov 3. doi: 10.1007/s10439-023-03392-x. Online ahead of print.ABSTRACTPatient-specific aortic geometry and its influence on the flow in the vicinity of Transcatheter Aortic Valve (TAV) has been highlighted in numerous studies using both in silico and in vitro experiments. However, there has not yet been a detailed Particle Image Velocimetry (PIV) experiment conducted to quantify the relationship between the geometry, flow downstream of TAV, and the flow in the sinus and the neo-sinus. We tested six different patient-specific aorta models with a 26-mm SAPIEN 3 valve (Edwards Lifesciences, Irvine, CA, US...
Source: Annals of Biomedical Engineering - November 3, 2023 Category: Biomedical Engineering Authors: Jae Hyun Kim Vahid Sadri Huang Chen Sanchita Bhat Keshav Kohli Raj Makkar Vasilis C Babaliaros Rahul P Sharma Ajit P Yoganathan Source Type: research

Venous Thromboembolism: Review of Clinical Challenges, Biology, Assessment, Treatment, and Modeling
Ann Biomed Eng. 2023 Nov 1. doi: 10.1007/s10439-023-03390-z. Online ahead of print.ABSTRACTVenous thromboembolism (VTE) is a massive clinical challenge, annually affecting millions of patients globally. VTE is a particularly consequential pathology, as incidence is correlated with extremely common risk factors, and a large cohort of patients experience recurrent VTE after initial intervention. Altered hemodynamics, hypercoagulability, and damaged vascular tissue cause deep-vein thrombosis and pulmonary embolism, the two permutations of VTE. Venous valves have been identified as likely locations for initial blood clot forma...
Source: Annals of Biomedical Engineering - November 2, 2023 Category: Biomedical Engineering Authors: Connor Watson Hicham Saaid Vijay Vedula Jessica C Cardenas Peter K Henke Franck Nicoud Xiao Yun Xu Beverley J Hunt Keefe B Manning Source Type: research

Correction: Evaluating the Intracranial Pressure Biofidelity and Response Repeatability of a Physical Head-Brain Model in Frontal Impacts
Ann Biomed Eng. 2023 Nov 2. doi: 10.1007/s10439-023-03395-8. Online ahead of print.NO ABSTRACTPMID:37917383 | DOI:10.1007/s10439-023-03395-8 (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - November 2, 2023 Category: Biomedical Engineering Authors: Yizhao Li Paris Vakiel Kevin Adanty Simon Ouellet Albert H Vette Donald Raboud Christopher R Dennison Source Type: research

Venous Thromboembolism: Review of Clinical Challenges, Biology, Assessment, Treatment, and Modeling
Ann Biomed Eng. 2023 Nov 1. doi: 10.1007/s10439-023-03390-z. Online ahead of print.ABSTRACTVenous thromboembolism (VTE) is a massive clinical challenge, annually affecting millions of patients globally. VTE is a particularly consequential pathology, as incidence is correlated with extremely common risk factors, and a large cohort of patients experience recurrent VTE after initial intervention. Altered hemodynamics, hypercoagulability, and damaged vascular tissue cause deep-vein thrombosis and pulmonary embolism, the two permutations of VTE. Venous valves have been identified as likely locations for initial blood clot forma...
Source: Annals of Biomedical Engineering - November 2, 2023 Category: Biomedical Engineering Authors: Connor Watson Hicham Saaid Vijay Vedula Jessica C Cardenas Peter K Henke Franck Nicoud Xiao Yun Xu Beverley J Hunt Keefe B Manning Source Type: research

Correction: Evaluating the Intracranial Pressure Biofidelity and Response Repeatability of a Physical Head-Brain Model in Frontal Impacts
Ann Biomed Eng. 2023 Nov 2. doi: 10.1007/s10439-023-03395-8. Online ahead of print.NO ABSTRACTPMID:37917383 | DOI:10.1007/s10439-023-03395-8 (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - November 2, 2023 Category: Biomedical Engineering Authors: Yizhao Li Paris Vakiel Kevin Adanty Simon Ouellet Albert H Vette Donald Raboud Christopher R Dennison Source Type: research