Parameterisation and Prediction of Intra-canal Cochlear Structures
Ann Biomed Eng. 2024 Jan 2. doi: 10.1007/s10439-023-03417-5. Online ahead of print.ABSTRACTAccurate 3D models of the cochlea are useful tools for research in the relationship between the electrode array and nerve fibres. The internal geometry of the cochlear canal plays an important role in understanding and quantifying that relationship. Predicting the location and shapes of the geometry is done by measuring histologic sections and fitting equations that can be used to predict parameters that fully define the geometry. A parameter sensitivity analysis is employed to prove that the size and location of the spiral lamina ar...
Source: Annals of Biomedical Engineering - January 2, 2024 Category: Biomedical Engineering Authors: Joshua Thiselton Tania Hanekom Source Type: research
Parameterisation and Prediction of Intra-canal Cochlear Structures
Ann Biomed Eng. 2024 Jan 2. doi: 10.1007/s10439-023-03417-5. Online ahead of print.ABSTRACTAccurate 3D models of the cochlea are useful tools for research in the relationship between the electrode array and nerve fibres. The internal geometry of the cochlear canal plays an important role in understanding and quantifying that relationship. Predicting the location and shapes of the geometry is done by measuring histologic sections and fitting equations that can be used to predict parameters that fully define the geometry. A parameter sensitivity analysis is employed to prove that the size and location of the spiral lamina ar...
Source: Annals of Biomedical Engineering - January 2, 2024 Category: Biomedical Engineering Authors: Joshua Thiselton Tania Hanekom Source Type: research
Parameterisation and Prediction of Intra-canal Cochlear Structures
Ann Biomed Eng. 2024 Jan 2. doi: 10.1007/s10439-023-03417-5. Online ahead of print.ABSTRACTAccurate 3D models of the cochlea are useful tools for research in the relationship between the electrode array and nerve fibres. The internal geometry of the cochlear canal plays an important role in understanding and quantifying that relationship. Predicting the location and shapes of the geometry is done by measuring histologic sections and fitting equations that can be used to predict parameters that fully define the geometry. A parameter sensitivity analysis is employed to prove that the size and location of the spiral lamina ar...
Source: Annals of Biomedical Engineering - January 2, 2024 Category: Biomedical Engineering Authors: Joshua Thiselton Tania Hanekom Source Type: research
Parameterisation and Prediction of Intra-canal Cochlear Structures
Ann Biomed Eng. 2024 Jan 2. doi: 10.1007/s10439-023-03417-5. Online ahead of print.ABSTRACTAccurate 3D models of the cochlea are useful tools for research in the relationship between the electrode array and nerve fibres. The internal geometry of the cochlear canal plays an important role in understanding and quantifying that relationship. Predicting the location and shapes of the geometry is done by measuring histologic sections and fitting equations that can be used to predict parameters that fully define the geometry. A parameter sensitivity analysis is employed to prove that the size and location of the spiral lamina ar...
Source: Annals of Biomedical Engineering - January 2, 2024 Category: Biomedical Engineering Authors: Joshua Thiselton Tania Hanekom Source Type: research
Effect of Blood Pressure Levels on Sinus Hemodynamics in Relation to Calcification After Bioprosthetic Aortic Valve Replacement
This study aims to investigate the effect of changing systolic and diastolic blood pressures (SBP and DBP, respectively) on sinus hemodynamics in relation to potential initiation or progression of CAVD after aortic valve replacement (AVR). Evolut R, SAPIEN 3 and Magna valves were deployed in an aortic root under pulsatile conditions. Using particle image velocimetry, the hemodynamics in the sinus were assessed. The velocity, vorticity, circulation ([Formula: see text] and shear stress were calculated. This study shows that under elevated SBP and DBP, velocity, vorticity, and shear stress nearby the leaflets increased. Addi...
Source: Annals of Biomedical Engineering - December 29, 2023 Category: Biomedical Engineering Authors: Brennan Vogl Agata Sularz Scott Lilly Vinod H Thourani Brian R Lindman Mohamad Alkhouli Hoda Hatoum Source Type: research
Aqueous Humor Circulation in the Era of Minimally Invasive Surgery for Glaucoma
Ann Biomed Eng. 2023 Dec 28. doi: 10.1007/s10439-023-03427-3. Online ahead of print.ABSTRACTGlaucoma surgery with implantation of aqueous humor draining microstents may compromise long-term corneal health by disrupting aqueous humor circulation. The effect of stent numbers on this circulation was interrogated to determine the number of stents associated with minimal circulation disruption. An in vitro anterior eye model perfusion system was constructed with multiple exit ports. A 3-D model of the anterior eye was imported into ABAQUS CFD, analyzes were carried out for unsteady laminar flow and solved using Navier-Stokes eq...
Source: Annals of Biomedical Engineering - December 28, 2023 Category: Biomedical Engineering Authors: Minas T Coroneo Gabriel Graterol-Nisi Eric Maver R Mark Gillies Source Type: research
Aqueous Humor Circulation in the Era of Minimally Invasive Surgery for Glaucoma
Ann Biomed Eng. 2023 Dec 28. doi: 10.1007/s10439-023-03427-3. Online ahead of print.ABSTRACTGlaucoma surgery with implantation of aqueous humor draining microstents may compromise long-term corneal health by disrupting aqueous humor circulation. The effect of stent numbers on this circulation was interrogated to determine the number of stents associated with minimal circulation disruption. An in vitro anterior eye model perfusion system was constructed with multiple exit ports. A 3-D model of the anterior eye was imported into ABAQUS CFD, analyzes were carried out for unsteady laminar flow and solved using Navier-Stokes eq...
Source: Annals of Biomedical Engineering - December 28, 2023 Category: Biomedical Engineering Authors: Minas T Coroneo Gabriel Graterol-Nisi Eric Maver R Mark Gillies Source Type: research
Aqueous Humor Circulation in the Era of Minimally Invasive Surgery for Glaucoma
Ann Biomed Eng. 2023 Dec 28. doi: 10.1007/s10439-023-03427-3. Online ahead of print.ABSTRACTGlaucoma surgery with implantation of aqueous humor draining microstents may compromise long-term corneal health by disrupting aqueous humor circulation. The effect of stent numbers on this circulation was interrogated to determine the number of stents associated with minimal circulation disruption. An in vitro anterior eye model perfusion system was constructed with multiple exit ports. A 3-D model of the anterior eye was imported into ABAQUS CFD, analyzes were carried out for unsteady laminar flow and solved using Navier-Stokes eq...
Source: Annals of Biomedical Engineering - December 28, 2023 Category: Biomedical Engineering Authors: Minas T Coroneo Gabriel Graterol-Nisi Eric Maver R Mark Gillies Source Type: research
Aqueous Humor Circulation in the Era of Minimally Invasive Surgery for Glaucoma
Ann Biomed Eng. 2023 Dec 28. doi: 10.1007/s10439-023-03427-3. Online ahead of print.ABSTRACTGlaucoma surgery with implantation of aqueous humor draining microstents may compromise long-term corneal health by disrupting aqueous humor circulation. The effect of stent numbers on this circulation was interrogated to determine the number of stents associated with minimal circulation disruption. An in vitro anterior eye model perfusion system was constructed with multiple exit ports. A 3-D model of the anterior eye was imported into ABAQUS CFD, analyzes were carried out for unsteady laminar flow and solved using Navier-Stokes eq...
Source: Annals of Biomedical Engineering - December 28, 2023 Category: Biomedical Engineering Authors: Minas T Coroneo Gabriel Graterol-Nisi Eric Maver R Mark Gillies Source Type: research
Determining the Mechanical Properties of Super-Elastic Nitinol Bone Staples Through an Integrated Experimental and Computational Calibration Approach
Ann Biomed Eng. 2023 Dec 27. doi: 10.1007/s10439-023-03416-6. Online ahead of print.ABSTRACTSuper-elastic bone staples have emerged as a safe and effective alternative for internal fixation. Nevertheless, several biomechanical aspects of super-elastic staples are still unclear and require further exploration. Within this context, this study presents a combined experimental and computational approach to investigate the mechanical characteristics of super-elastic staples. Two commercially available staples with distinct geometry, characterized by two and four legs, respectively, were examined. Experimental four-point bending...
Source: Annals of Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Dario Carbonaro Claudio Chiastra Federico A Bologna Alberto L Audenino Mara Terzini Source Type: research
Assessment of Mechanically Induced Changes in Helical Fiber Microstructure Using Diffusion Tensor Imaging
Ann Biomed Eng. 2023 Dec 27. doi: 10.1007/s10439-023-03420-w. Online ahead of print.ABSTRACTNoninvasive methods to detect microstructural changes in collagen-based fibrous tissues are necessary to differentiate healthy from damaged tissues in vivo but are sparse. Diffusion Tensor Imaging (DTI) is a noninvasive imaging technique used to quantitatively infer tissue microstructure with previous work primarily focused in neuroimaging applications. Yet, it is still unclear how DTI metrics relate to fiber microstructure and function in musculoskeletal tissues such as ligament and tendon, in part because of the high heterogeneity...
Source: Annals of Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Roberto Alonso Pineda Guzman Noel Naughton Shreyan Majumdar Bruce Damon Mariana E Kersh Source Type: research
Determining the Mechanical Properties of Super-Elastic Nitinol Bone Staples Through an Integrated Experimental and Computational Calibration Approach
Ann Biomed Eng. 2023 Dec 27. doi: 10.1007/s10439-023-03416-6. Online ahead of print.ABSTRACTSuper-elastic bone staples have emerged as a safe and effective alternative for internal fixation. Nevertheless, several biomechanical aspects of super-elastic staples are still unclear and require further exploration. Within this context, this study presents a combined experimental and computational approach to investigate the mechanical characteristics of super-elastic staples. Two commercially available staples with distinct geometry, characterized by two and four legs, respectively, were examined. Experimental four-point bending...
Source: Annals of Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Dario Carbonaro Claudio Chiastra Federico A Bologna Alberto L Audenino Mara Terzini Source Type: research
Assessment of Mechanically Induced Changes in Helical Fiber Microstructure Using Diffusion Tensor Imaging
Ann Biomed Eng. 2023 Dec 27. doi: 10.1007/s10439-023-03420-w. Online ahead of print.ABSTRACTNoninvasive methods to detect microstructural changes in collagen-based fibrous tissues are necessary to differentiate healthy from damaged tissues in vivo but are sparse. Diffusion Tensor Imaging (DTI) is a noninvasive imaging technique used to quantitatively infer tissue microstructure with previous work primarily focused in neuroimaging applications. Yet, it is still unclear how DTI metrics relate to fiber microstructure and function in musculoskeletal tissues such as ligament and tendon, in part because of the high heterogeneity...
Source: Annals of Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Roberto Alonso Pineda Guzman Noel Naughton Shreyan Majumdar Bruce Damon Mariana E Kersh Source Type: research
Comparison Between Effects of Galvanic and Vibration-Based Vestibular Stimulation on Postural Control and Gait Performance in Healthy Participants: A Systematic Review of Cross-Sectional Studies
This study aimed to systematically review the effects of galvanic (GVS) and vibration-based vestibular stimulation (VVS) on gait performance and postural control in healthy participants. Five bioscience and engineering databases, including MEDLINE via PubMed, CINAHL via EBSCO, Cochrane Library, Scopus, and Embase, were searched until March 19th, 2023. Studies published between 2000 and 2023 in English involving GVS and VVS related to gait performance and postural control were included. The procedure was followed via the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. The methodological qualit...
Source: Annals of Biomedical Engineering - December 26, 2023 Category: Biomedical Engineering Authors: Haoyu Xie Meizhen Liang Yujia Mo Cindy Schmidt Chuhuai Wang Jung Hung Chien Source Type: research
Comparison Between Effects of Galvanic and Vibration-Based Vestibular Stimulation on Postural Control and Gait Performance in Healthy Participants: A Systematic Review of Cross-Sectional Studies
This study aimed to systematically review the effects of galvanic (GVS) and vibration-based vestibular stimulation (VVS) on gait performance and postural control in healthy participants. Five bioscience and engineering databases, including MEDLINE via PubMed, CINAHL via EBSCO, Cochrane Library, Scopus, and Embase, were searched until March 19th, 2023. Studies published between 2000 and 2023 in English involving GVS and VVS related to gait performance and postural control were included. The procedure was followed via the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. The methodological qualit...
Source: Annals of Biomedical Engineering - December 26, 2023 Category: Biomedical Engineering Authors: Haoyu Xie Meizhen Liang Yujia Mo Cindy Schmidt Chuhuai Wang Jung Hung Chien Source Type: research
