Aqueous Humor Circulation in the Era of Minimally Invasive Surgery for Glaucoma
Ann Biomed Eng. 2023 Dec 28. doi: 10.1007/s10439-023-03427-3. Online ahead of print.ABSTRACTGlaucoma surgery with implantation of aqueous humor draining microstents may compromise long-term corneal health by disrupting aqueous humor circulation. The effect of stent numbers on this circulation was interrogated to determine the number of stents associated with minimal circulation disruption. An in vitro anterior eye model perfusion system was constructed with multiple exit ports. A 3-D model of the anterior eye was imported into ABAQUS CFD, analyzes were carried out for unsteady laminar flow and solved using Navier-Stokes eq...
Source: Annals of Biomedical Engineering - December 28, 2023 Category: Biomedical Engineering Authors: Minas T Coroneo Gabriel Graterol-Nisi Eric Maver R Mark Gillies Source Type: research
Aqueous Humor Circulation in the Era of Minimally Invasive Surgery for Glaucoma
Ann Biomed Eng. 2023 Dec 28. doi: 10.1007/s10439-023-03427-3. Online ahead of print.ABSTRACTGlaucoma surgery with implantation of aqueous humor draining microstents may compromise long-term corneal health by disrupting aqueous humor circulation. The effect of stent numbers on this circulation was interrogated to determine the number of stents associated with minimal circulation disruption. An in vitro anterior eye model perfusion system was constructed with multiple exit ports. A 3-D model of the anterior eye was imported into ABAQUS CFD, analyzes were carried out for unsteady laminar flow and solved using Navier-Stokes eq...
Source: Annals of Biomedical Engineering - December 28, 2023 Category: Biomedical Engineering Authors: Minas T Coroneo Gabriel Graterol-Nisi Eric Maver R Mark Gillies Source Type: research
Determining the Mechanical Properties of Super-Elastic Nitinol Bone Staples Through an Integrated Experimental and Computational Calibration Approach
Ann Biomed Eng. 2023 Dec 27. doi: 10.1007/s10439-023-03416-6. Online ahead of print.ABSTRACTSuper-elastic bone staples have emerged as a safe and effective alternative for internal fixation. Nevertheless, several biomechanical aspects of super-elastic staples are still unclear and require further exploration. Within this context, this study presents a combined experimental and computational approach to investigate the mechanical characteristics of super-elastic staples. Two commercially available staples with distinct geometry, characterized by two and four legs, respectively, were examined. Experimental four-point bending...
Source: Annals of Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Dario Carbonaro Claudio Chiastra Federico A Bologna Alberto L Audenino Mara Terzini Source Type: research
Assessment of Mechanically Induced Changes in Helical Fiber Microstructure Using Diffusion Tensor Imaging
Ann Biomed Eng. 2023 Dec 27. doi: 10.1007/s10439-023-03420-w. Online ahead of print.ABSTRACTNoninvasive methods to detect microstructural changes in collagen-based fibrous tissues are necessary to differentiate healthy from damaged tissues in vivo but are sparse. Diffusion Tensor Imaging (DTI) is a noninvasive imaging technique used to quantitatively infer tissue microstructure with previous work primarily focused in neuroimaging applications. Yet, it is still unclear how DTI metrics relate to fiber microstructure and function in musculoskeletal tissues such as ligament and tendon, in part because of the high heterogeneity...
Source: Annals of Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Roberto Alonso Pineda Guzman Noel Naughton Shreyan Majumdar Bruce Damon Mariana E Kersh Source Type: research
Determining the Mechanical Properties of Super-Elastic Nitinol Bone Staples Through an Integrated Experimental and Computational Calibration Approach
Ann Biomed Eng. 2023 Dec 27. doi: 10.1007/s10439-023-03416-6. Online ahead of print.ABSTRACTSuper-elastic bone staples have emerged as a safe and effective alternative for internal fixation. Nevertheless, several biomechanical aspects of super-elastic staples are still unclear and require further exploration. Within this context, this study presents a combined experimental and computational approach to investigate the mechanical characteristics of super-elastic staples. Two commercially available staples with distinct geometry, characterized by two and four legs, respectively, were examined. Experimental four-point bending...
Source: Annals of Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Dario Carbonaro Claudio Chiastra Federico A Bologna Alberto L Audenino Mara Terzini Source Type: research
Assessment of Mechanically Induced Changes in Helical Fiber Microstructure Using Diffusion Tensor Imaging
Ann Biomed Eng. 2023 Dec 27. doi: 10.1007/s10439-023-03420-w. Online ahead of print.ABSTRACTNoninvasive methods to detect microstructural changes in collagen-based fibrous tissues are necessary to differentiate healthy from damaged tissues in vivo but are sparse. Diffusion Tensor Imaging (DTI) is a noninvasive imaging technique used to quantitatively infer tissue microstructure with previous work primarily focused in neuroimaging applications. Yet, it is still unclear how DTI metrics relate to fiber microstructure and function in musculoskeletal tissues such as ligament and tendon, in part because of the high heterogeneity...
Source: Annals of Biomedical Engineering - December 27, 2023 Category: Biomedical Engineering Authors: Roberto Alonso Pineda Guzman Noel Naughton Shreyan Majumdar Bruce Damon Mariana E Kersh Source Type: research
Comparison Between Effects of Galvanic and Vibration-Based Vestibular Stimulation on Postural Control and Gait Performance in Healthy Participants: A Systematic Review of Cross-Sectional Studies
This study aimed to systematically review the effects of galvanic (GVS) and vibration-based vestibular stimulation (VVS) on gait performance and postural control in healthy participants. Five bioscience and engineering databases, including MEDLINE via PubMed, CINAHL via EBSCO, Cochrane Library, Scopus, and Embase, were searched until March 19th, 2023. Studies published between 2000 and 2023 in English involving GVS and VVS related to gait performance and postural control were included. The procedure was followed via the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. The methodological qualit...
Source: Annals of Biomedical Engineering - December 26, 2023 Category: Biomedical Engineering Authors: Haoyu Xie Meizhen Liang Yujia Mo Cindy Schmidt Chuhuai Wang Jung Hung Chien Source Type: research
Comparison Between Effects of Galvanic and Vibration-Based Vestibular Stimulation on Postural Control and Gait Performance in Healthy Participants: A Systematic Review of Cross-Sectional Studies
This study aimed to systematically review the effects of galvanic (GVS) and vibration-based vestibular stimulation (VVS) on gait performance and postural control in healthy participants. Five bioscience and engineering databases, including MEDLINE via PubMed, CINAHL via EBSCO, Cochrane Library, Scopus, and Embase, were searched until March 19th, 2023. Studies published between 2000 and 2023 in English involving GVS and VVS related to gait performance and postural control were included. The procedure was followed via the Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines. The methodological qualit...
Source: Annals of Biomedical Engineering - December 26, 2023 Category: Biomedical Engineering Authors: Haoyu Xie Meizhen Liang Yujia Mo Cindy Schmidt Chuhuai Wang Jung Hung Chien Source Type: research
In-Silico Analysis of Optimal Configurations for Rotational Bioinspired Bone Marrow Biopsy Needle Designs: An ANN Approach
This study analyzes the effects of six essential factors on insertion and extraction forces during bone marrow biopsy (BMB) procedures. The study uses Taguchi's L32 orthogonal array and numerically simulates the BMB process using the Lagrangian surface-based method on a three-dimensional (3D) heterogeneous Finite Element (FE) model of the human iliac crest. The study evaluates cutting forces in needle insertion and extraction using uni-directional (360° rotation) and bidirectional (180° clock and anti-clock rotation) bioinspired BMB needles. This work aims to create an AI tool that assists researchers and clinicians in s...
Source: Annals of Biomedical Engineering - December 22, 2023 Category: Biomedical Engineering Authors: Rahul Nadda Ramjee Repaka Source Type: research
In-Silico Analysis of Optimal Configurations for Rotational Bioinspired Bone Marrow Biopsy Needle Designs: An ANN Approach
This study analyzes the effects of six essential factors on insertion and extraction forces during bone marrow biopsy (BMB) procedures. The study uses Taguchi's L32 orthogonal array and numerically simulates the BMB process using the Lagrangian surface-based method on a three-dimensional (3D) heterogeneous Finite Element (FE) model of the human iliac crest. The study evaluates cutting forces in needle insertion and extraction using uni-directional (360° rotation) and bidirectional (180° clock and anti-clock rotation) bioinspired BMB needles. This work aims to create an AI tool that assists researchers and clinicians in s...
Source: Annals of Biomedical Engineering - December 22, 2023 Category: Biomedical Engineering Authors: Rahul Nadda Ramjee Repaka Source Type: research
In-Silico Analysis of Optimal Configurations for Rotational Bioinspired Bone Marrow Biopsy Needle Designs: An ANN Approach
This study analyzes the effects of six essential factors on insertion and extraction forces during bone marrow biopsy (BMB) procedures. The study uses Taguchi's L32 orthogonal array and numerically simulates the BMB process using the Lagrangian surface-based method on a three-dimensional (3D) heterogeneous Finite Element (FE) model of the human iliac crest. The study evaluates cutting forces in needle insertion and extraction using uni-directional (360° rotation) and bidirectional (180° clock and anti-clock rotation) bioinspired BMB needles. This work aims to create an AI tool that assists researchers and clinicians in s...
Source: Annals of Biomedical Engineering - December 22, 2023 Category: Biomedical Engineering Authors: Rahul Nadda Ramjee Repaka Source Type: research
Injury Risk for the Hand and Forearm Under Loading Representative of Behind Shield Blunt Trauma
This study is the first known investigation of the upper extremity to this high loading rate scenario and provides the foundation for future biomechanical research in the area of behind shield blunt trauma.PMID:38127287 | DOI:10.1007/s10439-023-03418-4 (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - December 21, 2023 Category: Biomedical Engineering Authors: J E de Lange L Burrows A Wadera C E Quenneville Source Type: research
Injury Risk for the Hand and Forearm Under Loading Representative of Behind Shield Blunt Trauma
This study is the first known investigation of the upper extremity to this high loading rate scenario and provides the foundation for future biomechanical research in the area of behind shield blunt trauma.PMID:38127287 | DOI:10.1007/s10439-023-03418-4 (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - December 21, 2023 Category: Biomedical Engineering Authors: J E de Lange L Burrows A Wadera C E Quenneville Source Type: research
Insight into Automatic Image Diagnosis of Ear Conditions Based on Optimized Deep Learning Approach
Ann Biomed Eng. 2023 Dec 14. doi: 10.1007/s10439-023-03422-8. Online ahead of print.ABSTRACTExamining otoscopic images for ear diseases is necessary when the clinical diagnosis of ear diseases extracted from the knowledge of otolaryngologists is limited. Improved diagnosis approaches based on otoscopic image processing are urgently needed. Recently, convolutional neural networks (CNNs) have been carried out for medical diagnosis to obtain higher accuracy than standard machine learning algorithms and specialists' expertise. Therefore, the proposed approach involves using the Bayesian hyperparameter optimization with the CNN...
Source: Annals of Biomedical Engineering - December 15, 2023 Category: Biomedical Engineering Authors: Heba M Afify Kamel K Mohammed Aboul Ella Hassanien Source Type: research
Effect of Sinotubular Junction Size on TAVR Leaflet Thrombosis: A Fluid-Structure Interaction Analysis
Ann Biomed Eng. 2023 Dec 14. doi: 10.1007/s10439-023-03419-3. Online ahead of print.ABSTRACTTAVR has emerged as a standard approach for treating severe aortic stenosis patients. However, it is associated with several clinical complications, including subclinical leaflet thrombosis characterized by Hypoattenuated Leaflet Thickening (HALT). A rigorous analysis of TAVR device thrombogenicity considering anatomical variations is essential for estimating this risk. Clinicians use the Sinotubular Junction (STJ) diameter for TAVR sizing, but there is a paucity of research on its influence on TAVR devices thrombogenicity. A Medtro...
Source: Annals of Biomedical Engineering - December 15, 2023 Category: Biomedical Engineering Authors: David Oks Symon Reza Mariano V ázquez Guillaume Houzeaux Brandon Kovarovic Crist óbal Samaniego Danny Bluestein Source Type: research
