Characterizing Natural Frequencies of the Hybrid III and NOCSAE Headforms
This study aimed to identify the natural frequencies of each headform through experimental modal analysis techniques. An impulse hammer was used to excite various locations on both the Hybrid III and NOCSAE headforms. The resulting frequency response functions were analyzed to determine the first natural frequencies. The average first natural frequency of the NOCSAE headform was 812 Hz. The Hybrid III headform did not exhibit any natural frequencies below 1000 Hz. Comparisons of our results with previous studies of the human head suggest that the NOCSAE headform's vibrational response aligns more closely with that of the h...
Source: Annals of Biomedical Engineering - April 1, 2024 Category: Biomedical Engineering Authors: Kristin J Dingelstedt Steve Rowson Source Type: research

Scan-Free and Fully Automatic Tracking of Native Knee Anatomy from Dynamic Stereo-Radiography with Statistical Shape and Intensity Models
Ann Biomed Eng. 2024 Apr 1. doi: 10.1007/s10439-024-03473-5. Online ahead of print.ABSTRACTKinematic tracking of native anatomy from stereo-radiography provides a quantitative basis for evaluating human movement. Conventional tracking procedures require significant manual effort and call for acquisition and annotation of subject-specific volumetric medical images. The current work introduces a framework for fully automatic tracking of native knee anatomy from dynamic stereo-radiography which forgoes reliance on volumetric scans. The method consists of three computational steps. First, captured radiographs are annotated wit...
Source: Annals of Biomedical Engineering - April 1, 2024 Category: Biomedical Engineering Authors: William Burton Casey Myers Margareta Stefanovic Kevin Shelburne Paul Rullkoetter Source Type: research

Investigating the Effects of a Kinematic Gait Parameter-Based Haptic Cue on Toe Clearance in Parkinson's Patients
Ann Biomed Eng. 2024 Mar 30. doi: 10.1007/s10439-024-03501-4. Online ahead of print.ABSTRACTRecurrent falls pose a significant challenge for Parkinson's disease (PD) patients and are a leading cause of disability in this population. One contributing factor to these recurring falls is the reduced minimum toe clearance (mTC). Preventing such falls by enhancing mTC has become an important goal in gait training among PD patients. In this paper, we propose a wearable cueing-based novel gait training device in anticipation of improved mTC. The cueing device records the foot strike angle (FSA) and cues the participants if the FSA...
Source: Annals of Biomedical Engineering - March 30, 2024 Category: Biomedical Engineering Authors: Rohan Khatavkar Ashutosh Tiwari Priyanka Bhat Deepak Joshi Source Type: research

Investigating the Effects of a Kinematic Gait Parameter-Based Haptic Cue on Toe Clearance in Parkinson's Patients
Ann Biomed Eng. 2024 Mar 30. doi: 10.1007/s10439-024-03501-4. Online ahead of print.ABSTRACTRecurrent falls pose a significant challenge for Parkinson's disease (PD) patients and are a leading cause of disability in this population. One contributing factor to these recurring falls is the reduced minimum toe clearance (mTC). Preventing such falls by enhancing mTC has become an important goal in gait training among PD patients. In this paper, we propose a wearable cueing-based novel gait training device in anticipation of improved mTC. The cueing device records the foot strike angle (FSA) and cues the participants if the FSA...
Source: Annals of Biomedical Engineering - March 30, 2024 Category: Biomedical Engineering Authors: Rohan Khatavkar Ashutosh Tiwari Priyanka Bhat Deepak Joshi Source Type: research

Simulating Cerebral Edema and Ischemia After Traumatic Acute Subdural Hematoma Using Triphasic Swelling Biomechanics
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03496-y. Online ahead of print.ABSTRACTPoor outcome following traumatic acute subdural hematoma (ASDH) is associated with the severity of the primary injury and secondary injury including cerebral edema and ischemia. However, the underlying secondary injury mechanism contributing to elevated intracranial pressure (ICP) and high mortality rate remains unclear. Cerebral edema occurs in response to the exposure of the intracellular fixed charge density (FCD) after cell death, causing ICP to increase. The increased ICP from swollen tissue compresses blood vessels in adjacent...
Source: Annals of Biomedical Engineering - March 27, 2024 Category: Biomedical Engineering Authors: Andrew V Basilio Delin Zeng Leanne A Pichay Gerard A Ateshian Peng Xu Steve A Maas Barclay Morrison Source Type: research

The 'bIUreactor': An Open-Source 3D Tissue Research Platform
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03481-5. Online ahead of print.ABSTRACTWe developed the open-source bIUreactor research platform for studying 3D structured tissues. The versatile and modular platform allows a researcher to generate 3D tissues, culture them with oxygenated perfusion, and provide cyclic loading, all in their own lab (in laboratorium) for an all in cost of $8,000 including 3D printer, printing resin, and electronics. We achieved this by applying a design philosophy that leverages 3D printing, open-source software and hardware, and practical techniques to produce the following: 1. perfusib...
Source: Annals of Biomedical Engineering - March 27, 2024 Category: Biomedical Engineering Authors: Elizabeth Butch Matthew Prideaux Mark Holland Justin-Thuy Phan Cole Trent Victor Soon Gary Hutchins Lester Smith Source Type: research

Simulating Cerebral Edema and Ischemia After Traumatic Acute Subdural Hematoma Using Triphasic Swelling Biomechanics
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03496-y. Online ahead of print.ABSTRACTPoor outcome following traumatic acute subdural hematoma (ASDH) is associated with the severity of the primary injury and secondary injury including cerebral edema and ischemia. However, the underlying secondary injury mechanism contributing to elevated intracranial pressure (ICP) and high mortality rate remains unclear. Cerebral edema occurs in response to the exposure of the intracellular fixed charge density (FCD) after cell death, causing ICP to increase. The increased ICP from swollen tissue compresses blood vessels in adjacent...
Source: Annals of Biomedical Engineering - March 27, 2024 Category: Biomedical Engineering Authors: Andrew V Basilio Delin Zeng Leanne A Pichay Gerard A Ateshian Peng Xu Steve A Maas Barclay Morrison Source Type: research

The 'bIUreactor': An Open-Source 3D Tissue Research Platform
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03481-5. Online ahead of print.ABSTRACTWe developed the open-source bIUreactor research platform for studying 3D structured tissues. The versatile and modular platform allows a researcher to generate 3D tissues, culture them with oxygenated perfusion, and provide cyclic loading, all in their own lab (in laboratorium) for an all in cost of $8,000 including 3D printer, printing resin, and electronics. We achieved this by applying a design philosophy that leverages 3D printing, open-source software and hardware, and practical techniques to produce the following: 1. perfusib...
Source: Annals of Biomedical Engineering - March 27, 2024 Category: Biomedical Engineering Authors: Elizabeth Butch Matthew Prideaux Mark Holland Justin-Thuy Phan Cole Trent Victor Soon Gary Hutchins Lester Smith Source Type: research

Simulating Cerebral Edema and Ischemia After Traumatic Acute Subdural Hematoma Using Triphasic Swelling Biomechanics
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03496-y. Online ahead of print.ABSTRACTPoor outcome following traumatic acute subdural hematoma (ASDH) is associated with the severity of the primary injury and secondary injury including cerebral edema and ischemia. However, the underlying secondary injury mechanism contributing to elevated intracranial pressure (ICP) and high mortality rate remains unclear. Cerebral edema occurs in response to the exposure of the intracellular fixed charge density (FCD) after cell death, causing ICP to increase. The increased ICP from swollen tissue compresses blood vessels in adjacent...
Source: Annals of Biomedical Engineering - March 27, 2024 Category: Biomedical Engineering Authors: Andrew V Basilio Delin Zeng Leanne A Pichay Gerard A Ateshian Peng Xu Steve A Maas Barclay Morrison Source Type: research

The 'bIUreactor': An Open-Source 3D Tissue Research Platform
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03481-5. Online ahead of print.ABSTRACTWe developed the open-source bIUreactor research platform for studying 3D structured tissues. The versatile and modular platform allows a researcher to generate 3D tissues, culture them with oxygenated perfusion, and provide cyclic loading, all in their own lab (in laboratorium) for an all in cost of $8,000 including 3D printer, printing resin, and electronics. We achieved this by applying a design philosophy that leverages 3D printing, open-source software and hardware, and practical techniques to produce the following: 1. perfusib...
Source: Annals of Biomedical Engineering - March 27, 2024 Category: Biomedical Engineering Authors: Elizabeth Butch Matthew Prideaux Mark Holland Justin-Thuy Phan Cole Trent Victor Soon Gary Hutchins Lester Smith Source Type: research

Simulating Cerebral Edema and Ischemia After Traumatic Acute Subdural Hematoma Using Triphasic Swelling Biomechanics
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03496-y. Online ahead of print.ABSTRACTPoor outcome following traumatic acute subdural hematoma (ASDH) is associated with the severity of the primary injury and secondary injury including cerebral edema and ischemia. However, the underlying secondary injury mechanism contributing to elevated intracranial pressure (ICP) and high mortality rate remains unclear. Cerebral edema occurs in response to the exposure of the intracellular fixed charge density (FCD) after cell death, causing ICP to increase. The increased ICP from swollen tissue compresses blood vessels in adjacent...
Source: Annals of Biomedical Engineering - March 27, 2024 Category: Biomedical Engineering Authors: Andrew V Basilio Delin Zeng Leanne A Pichay Gerard A Ateshian Peng Xu Steve A Maas Barclay Morrison Source Type: research

The 'bIUreactor': An Open-Source 3D Tissue Research Platform
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03481-5. Online ahead of print.ABSTRACTWe developed the open-source bIUreactor research platform for studying 3D structured tissues. The versatile and modular platform allows a researcher to generate 3D tissues, culture them with oxygenated perfusion, and provide cyclic loading, all in their own lab (in laboratorium) for an all in cost of $8,000 including 3D printer, printing resin, and electronics. We achieved this by applying a design philosophy that leverages 3D printing, open-source software and hardware, and practical techniques to produce the following: 1. perfusib...
Source: Annals of Biomedical Engineering - March 27, 2024 Category: Biomedical Engineering Authors: Elizabeth Butch Matthew Prideaux Mark Holland Justin-Thuy Phan Cole Trent Victor Soon Gary Hutchins Lester Smith Source Type: research

An Experimental Phototherapy Device for Studying the Effects of Blue Light on Patients with Raynaud's Phenomenon
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03487-z. Online ahead of print.ABSTRACTRaynaud's phenomenon (RP) is a condition that causes decreased blood flow to areas perfused by small blood vessels (e.g., fingers, toes). In severe cases, ulceration, gangrene, and loss of fingers may occur. Most treatments focus on inducing vasorelaxation in affected areas by the way of pharmaceuticals. Recently, animal studies have shown that vasorelaxation can be induced by non-coherent blue light (wavelength ~ 430-460 nm) through the actions of melanopsin, a photoreceptive opsin protein encoded by the OPN4 gene. To study this ef...
Source: Annals of Biomedical Engineering - March 26, 2024 Category: Biomedical Engineering Authors: Brett Levac James Kerber Emily Wagner Jerry A Molitor Steven S Saliterman Source Type: research

Tibiofemoral Slip Velocity in Total Knee Arthroplasty is Design-Invariant but Activity-Dependent
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03490-4. Online ahead of print.ABSTRACTTibiofemoral slip velocity is a key contributor to total knee arthroplasty (TKA) component wear, yet few studies have evaluated this quantity in vivo. The aim of the present study was to measure and compare tibiofemoral slip velocities in 3 TKA designs for a range of daily activities. Mobile biplane X-ray imaging was used to measure 6-degree-of-freedom tibiofemoral kinematics and the locations of articular contact in 75 patients implanted with a posterior-stabilized, cruciate-retaining, or medial-stabilized design while each patient...
Source: Annals of Biomedical Engineering - March 26, 2024 Category: Biomedical Engineering Authors: Shanyuanye Guan Raphael Dumas Marcus G Pandy Source Type: research

A Survey of Needle Steering Approaches in Minimally Invasive Surgery
Ann Biomed Eng. 2024 Mar 26. doi: 10.1007/s10439-024-03494-0. Online ahead of print.ABSTRACTIn virtue of a curved insertion path inside tissues, needle steering techniques have revealed the potential with the assistance of medical robots and images. The superiority of this technique has been preliminarily verified with several maneuvers: target realignment, obstacle circumvention, and multi-target access. However, the momentum of needle steering approaches in the past decade leads to an open question-"How to choose an applicable needle steering approach for a specific clinical application?" This survey discusses this quest...
Source: Annals of Biomedical Engineering - March 26, 2024 Category: Biomedical Engineering Authors: Yuzhou Duan Jie Ling Zhao Feng Tingting Ye Tairen Sun Yuchuan Zhu Source Type: research