Factors associated with delayed enteral nutrition in the intensive care unit: a propensity score –matched retrospective cohort study
ConclusionsProvider-level factors were associated with delayed ordering of EN which itself was associated with worse outcomes. Interventions directed at providers may increase timely EN in the ICU and improve outcomes. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Plasma glycerophospholipid profile, erythrocyte n –3 PUFAs, and metabolic syndrome incidence: a prospective study in Chinese men and women
ConclusionsElevated plasma concentrations of GPs, especially PEs with LCPUFAs or VLCPUFAs at thesn-2 position, are associated with higher risk of incident MetS. Future studies are merited to confirm our findings. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Genetically determined SCFA concentration modifies the association of dietary fiber intake with changes in bone mineral density during weight loss: The Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial
ConclusionsOur data indicate that genetic variants related to butyrate modify the relations of dietary fiber intake and sex with long-term changes in BMD in response to weight-loss diet interventions. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Factors associated with small- and large-for-gestational-age in socioeconomically vulnerable individuals in the 100 Million Brazilian Cohort
ConclusionsIn poorer Brazilian populations, socioeconomic, racial, and maternal characteristics are consistently associated with the occurrence of SGA births, but remain less clearly linked to the occurrence of LGA births. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Gut microbiota –derived metabolites and risk of coronary artery disease: a prospective study among US men and women
ConclusionsOur results show that a profile characterized by high enterolactone and low TMAO concentrations in plasma is linked to a healthful dietary pattern and significantly associated with a lower risk of CAD. Overall, these data suggest that, compared with individual markers, multiple microbiota-derived metabolites may facilitate better differentiation of CAD risk and characterization of the relations between diet, microbiota, and CAD risk. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Zinc absorption and zinc status are reduced after either sleeve gastrectomy or Roux-en-Y gastric bypass in premenopausal women with severe obesity studied prospectively over 24 postoperative months
ConclusionsBoth SG and RYGBP have profound effects on zinc absorption capacity, which are not compensated for after 24 mo. Although zinc absorption reduction was similar in both types of surgeries, plasma zinc was more affected in RYGBP than SG, despite greater zinc supplementation in RYGBP.This trial was registered athttp://www.isrctn.com as ISRCTN31937503. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Eggs, dietary cholesterol, choline, betaine, and diabetes risk in the Women's Health Initiative: a prospective analysis
ConclusionsAs egg consumption increased to ≥3 eggs/wk, there was a steady increase in diabetes risk that may have been due to the cholesterol in the eggs. The population attributable risk for ≥3 eggs/wk was far lower than that for being obese or overweight. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

A comparison of complementary measures of vitamin B6 status, function, and metabolism in the European Prospective Investigation into Cancer and Nutrition (EPIC) study
ConclusionsWe found that 5 different markers, capturing different aspects of vitamin B6 –related biological processes, varied in their associations with vitamin B6 intake and personal and lifestyle predictors. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Low-dose thiamine supplementation of lactating Cambodian mothers improves human milk thiamine concentrations: a randomized controlled trial
ConclusionsA supplemental thiamine dose of 2.35 mg/d was required to achieve a milk total thiamine concentration of 191 µg/L. However, 1.2 mg/d for 22 wk was sufficient to increase milk thiamine concentrations to similar levels achieved by higher supplementation doses (2.4 and 10 mg/d), and comparable to those of healthy mothers in regions without beriberi. This trial was registered atclinicaltrials.gov as NCT03616288. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Breastfeeding and wheeze-related outcomes in high-risk infants: A systematic review and meta-analysis
ConclusionsBreastfeeding was associated with reduced odds of wheezing in high-risk infants, with the strongest protection in the first 6 months. More research is needed to understand the impact of breastfeeding intensity on wheezing and to examine additional respiratory outcomes, including wheeze severity. This review was registered at PROSPERO as CRD42019118631. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Anemia in pregnant women with HIV: Insights and implications about iron for all pregnant women and infants
See corresponding article onpage 1402. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Effect of varying quantities of lean beef as part of a Mediterranean-style dietary pattern on lipids and lipoproteins: a randomized crossover controlled feeding trial
ConclusionsLipid and lipoprotein lowering was not attenuated with the inclusion of lean beef in amounts ≤71 g (2.5 oz)/d as part of a healthy low-saturated-fat Mediterranean-style diet.This study is registered atclinicaltrials.gov as NCT02723617. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Circulating trimethylamine N-oxide in association with diet and cardiometabolic biomarkers: an international pooled analysis
ConclusionsIn an international, consortium-based study, animal protein was consistently associated with increased circulating TMAO, whereas TMAO associations with fish, shellfish, eggs, and red meat varied among populations. The adverse associations of TMAO with certain cardiometabolic biomarkers, independent of renal function, warrant further investigation. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Retinol isotope dilution applications in the field: annotating the user's guide from recent experiences
See corresponding article onpage 1209. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research

Essentially essential
See corresponding article onpage 1256. (Source: American Journal of Clinical Nutrition)
Source: American Journal of Clinical Nutrition - April 7, 2021 Category: Nutrition Source Type: research