EBUS-TBNA: A 2-Year Experience from a Tertiary Pathology Centre with Cyto-Histological Correlation
Conclusions: The EBUS-TBNA diagnostic yield, diagnostic accuracy, and inadequate rate in the present study are in line with previously published studies.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - May 19, 2022 Category: Cytology Source Type: research
Effects of Rapid On-Site Evaluation on Diagnostic Accuracy of Thyroid Fine-Needle Aspiration
Conclusions: Implementation of ROSE of thyroid nodule specimen improved diagnostic adequacy of FNA, reducing nondiagnostic findings. However, due to increased equivocal findings (Bethesda category III), there was no significant reduction of repeat FNA.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - May 5, 2022 Category: Cytology Source Type: research
Correlation of Morphological Features of Chromosomal Instability and Flow Cytometric DNA Ploidy Analysis in Aspirates of Breast Carcinoma
Conclusions: Morphological evaluation of CI by light microscopy on routinely stained breast aspirates is feasible, although a meticulous search is required. Cytomorphological features of CI and ploidy have a positive correlation with increasing tumor grade.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - April 22, 2022 Category: Cytology Source Type: research
Clinical Management of Atypical Endometrial Cells of Undetermined Significance Followed by Negative Cytology
Conclusion: No patient developed ATEC-A or worse within 1 year. For patients with ATEC-US, if negative cytology is obtained at the next examination, a close follow-up is not necessary.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - April 14, 2022 Category: Cytology Source Type: research
The Small Round Cell Sarcomas Complexities and Desmoplastic Presentation
Background: Small round cell sarcomas (SRCSs) account for most solid malignancies in the pediatric age group and are a part of group of malignant tumors characterized by heterogenous clinical presentation and overlapping microscopic features of small, round, primitive cells. In addition to the recently established certain genetically defined subset of undifferentiated round cell sarcomas of soft tissue and bone, this group of sarcomas include desmoplastic small round cell tumor, poorly differentiated synovial sarcoma, alveolar rhabdomyosarcoma, mesenchymal chondrosarcoma, and small cell osteosarcoma. Although, those entiti...
Source: Acta Cytologica - April 13, 2022 Category: Cytology Source Type: research
Risk Stratification of Pleural Fluid Cytology Based on the International System for Reporting Serous Fluid Cytology in a Tertiary Care Centre
Conclusion: Cytological examination of pleural fluids is an accurate, prompt, and affordable technique. This standardized ISRSFC reporting system will maintain uniformity and reproducibility in reporting, leading to improved clinical decision-making of pleural fluids.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - April 12, 2022 Category: Cytology Source Type: research
Optimal Preservations of Cytological Materials Using Liquid-Based Cytology Fixatives for Next-Generation Sequencing Analysis
Conclusion: LBC-CB preparation is an effective method to maintain DNA/RNA quality and quantity in long-duration preservation for eventual molecular testing. Therefore, LBC-CB may have applications on preanalytical stage for molecular genomic testing such as next-generation sequencing.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - April 12, 2022 Category: Cytology Source Type: research
Lung and Mediastinal Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Young Adults
Conclusion: In young adults, EBUS-TBNA was most frequently performed to evaluate lymphadenopathy and lung nodules, and granulomatous disease was the most common benign finding. Although rare, primary lung malignancies do occur in young adults along with metastasis from a variety of other sites, with sarcoma being the most common pathology.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - April 7, 2022 Category: Cytology Source Type: research
Cytological Diagnosis of Aggressive Small-Cell Lymphomas
Background: Despite their sometimes deceivingly bland appearance, some small-cell lymphomas are very aggressive and the prognosis of patients depends on a prompt diagnosis that allows the initiation of appropriate therapy.Summary: The present review discusses the salient cytological features of the most common aggressive small-cell lymphomas and then proceeds to analyze their main diagnostic criteria, including the usage of ancillary techniques.Key Messages: Lymph node fine-needle aspiration cytology is a fast, safe, cheap, minimally invasive, and accurate procedure that can be used for a prompt and accurate diagnosis of l...
Source: Acta Cytologica - April 6, 2022 Category: Cytology Source Type: research
Urinary Podocyte Count as a Potential Routine Laboratory Test for Glomerular Disease: A Novel Method Using Liquid-Based Cytology and Immunoenzyme Staining
Conclusion: Because our urinary podocyte detection method using PDX immunoenzyme staining can be standardized and it detected glomerular disease with high accuracy, it can likely serve as a noninvasive routine laboratory test for various glomerular diseases.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - March 29, 2022 Category: Cytology Source Type: research
Erratum
Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - March 29, 2022 Category: Cytology Source Type: research
Characteristics of Pelvic Cytology in Patients with Gynecologic Malignancies: Comparison of Pre and Post-Neoadjuvant Specimens
Conclusion: No identifiable trend was noted regarding cellularity of specimens in the pre compared to the post-neoadjuvant setting. A trend toward reduced cellularity was noted in individual patients, but no alteration in background cells or tumor morphology was noted.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - March 25, 2022 Category: Cytology Source Type: research
Impact of Human Papillomavirus on Wnt/Beta-Catenin Signaling in Morphological Inconspicuous Cervicovaginal Cells
Conclusion: In conclusion, the activation of the Wnt/beta-catenin signaling pathway and upregulation of sFRP4, paralleled by an activation of the autophagic pathway may represent predisposing cellular factors early after HPV infection which need to be further determined in larger study.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - March 18, 2022 Category: Cytology Source Type: research
Role of Pathologist in the Era of Image-Guided and EUS-Guided Aspirations: A 10-Year Study at a Single Tertiary Care Oncology Institute in North India
Conclusion: The utility of ROSE and diminishing role of pathologist is highlighted in our study. Judicious ROSE improves diagnostic accuracy, decreases the rate of missed diagnosis and the repetition of procedures. The study sheds light on the ever-increasing lacuna in the training of pathologists for blind as well as in image-guided FNAC. Further, it enumerates the factors leading to the underutilization of ROSE, its undisputed advantages, operator variations in procedure, smear preparation, and screening.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - March 10, 2022 Category: Cytology Source Type: research
Geographic Distribution, Number, and Types of Papers Published in International Cytopathology Journals in the Last 5.5 Years: A Preliminary Study
Conclusion: The number of academic papers originating from developing countries in the field of cytopathology has increased in recent years. Although most scientific papers are produced in developed countries, the rate in these countries is much lower than that in some developing countries as the rate of academic growth in developed countries has stabilized. Despite the widespread and sophisticated implementation of cytology in daily practice in Western European countries outside the UK, such as Germany and the Netherlands, and in Scandinavian countries and other developed countries, such as Australia and Canada, these cou...
Source: Acta Cytologica - March 4, 2022 Category: Cytology Source Type: research
