Fractal Analysis Method for the Complexity of Cell Cluster Staining on Breast FNAB
Conclusion: Cluster gray image-fractal analysis evaluating the darkness of clusters, cluster unevenness, and complexity of cluster density in breast FNAB HCG is a useful cytology assistance system for breast FNA.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - August 25, 2020 Category: Cytology Source Type: research
Papanicolaou Staining and Processing Troubleshooting Exercise Using Digital Pathology: Peer Comparison in an External Quality Assurance Setting
Conclusions: Quality cytopathology preparatory techniques are integral to mitigating the risk of diagnostic error. The digital pathology platform allowed homogeneity of samples for all participants and appeared to be a satisfactory mode for demonstrating the technical problems to participants. Laboratories participating in this survey showed good performance in identifying processing and staining problems on virtual images and working through the troubleshooting steps. The exercise also identified a method for troubleshooting formalin vapour-affected slides using citrate buffer which may be useful for laboratories followin...
Source: Acta Cytologica - August 21, 2020 Category: Cytology Source Type: research
Characteristic Cytological Findings of Lobular Endocervical Glandular Hyperplasia Associated with Adenocarcinoma of the Uterine Cervix
Conclusions: LEGH is found to be associated with adenocarcinoma types other than MC-G. Complex glandular structures or mucin localization on the surface of glandular cell clusters may be useful cytological findings to detect atypical and mixed types of LEGH.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - August 19, 2020 Category: Cytology Source Type: research
Putative Malignant Pleural Mesothelioma in situ (MPMIS) with Sequential Acquisition of Genomic Alterations on Fluorescence in situ Hybridization (FISH) Examination
Malignant pleural mesothelioma (MPM) is a rare and deadly disease. A precursor in situ lesion, malignant pleural mesothelioma in situ (MPMIS), has recently been proposed. On cytological examination, the distinction between reactive and malignant mesothelial cells is often challenging, and sometimes even impossible without ancillary methods. Fluorescence in situ hybridization (FISH) for detection of 9p21 deletion is a powerful diagnostic tool in this context, both in histological and in cytological specimens. Here, we present a case of MPM with initial presentation as a putative MPMIS with disomic chromosomal pattern and ho...
Source: Acta Cytologica - August 19, 2020 Category: Cytology Source Type: research
COVID-19 and Peripheral Smear Chat
Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - August 14, 2020 Category: Cytology Source Type: research
Correlation of High-Risk HPV Genotypes with Pap Test Findings: A Retrospective Study in Eastern Province, Saudi Arabia
Conclusion: HR HPV frequency and genotype distribution, in this study, might reflect a different regional infection pattern. The high association of HR HPV with negative cytology emphasizes the need to add the HR HPV test to screening modalities of cervix cancer.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - August 12, 2020 Category: Cytology Source Type: research
Erratum
Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - August 5, 2020 Category: Cytology Source Type: research
Morphogo: An Automatic Bone Marrow Cell Classification System on Digital Images Analyzed by Artificial Intelligence
Conclusion: This pilot study confirmed that theMorphogo system is a reliable tool for automatic bone marrow cell differential count analysis and has potential for clinical applications. Current ongoing large-scale multicenter validation studies will provide more information to further confirm the clinical utility of the system.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - July 28, 2020 Category: Cytology Source Type: research
Clinical and Morphological Spectrum of Histoplasmosis on Cytology Along with the Review of Literature
Conclusion: Fine needle aspiration is a highly accurate, rapid, and cheap technique for the diagnosis of histoplasmosis due to its distinct morphological features.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - July 23, 2020 Category: Cytology Source Type: research
Computational Cytology: Lessons Learned from Pap Test Computer-Assisted Screening
Background: In the face of rapid technological advances in computational cytology including artificial intelligence (AI), optimization of its application to clinical practice would benefit from reflection on the lessons learned from the decades-long journey in the development of computer-assisted Pap test screening.Summary: The initial driving force for automated screening in cytology was the overwhelming number of Pap tests requiring manual screening, leading to workflow backlogs and incorrect diagnoses. Several companies invested resources to address these concerns utilizing different specimen processing techniques and i...
Source: Acta Cytologica - July 21, 2020 Category: Cytology Source Type: research
PIK3CA Mutations and Their Impact on Survival Outcomes of Patients with Cervical Cancer: A Systematic Review
Conclusion: Current evidence concerning the impact of PIK3CA mutations on survival outcomes of patients with cervical cancer is inconclusive, although the majority of included studies support a potential negative effect, primarily among those with squamous cell carcinoma tumors.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - July 17, 2020 Category: Cytology Source Type: research
Computational Technology with Artificial Intelligence and Machine Learning: What Should a Cytologist Do with It?
Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - July 8, 2020 Category: Cytology Source Type: research
Journal Impact Factor Returned to < b > < i > Acta < /i > < /b > < b > < i > Cytologica < /i > < /b > in 2020
Acta Cytologica 2020;64:280 (Source: Acta Cytologica)
Source: Acta Cytologica - June 29, 2020 Category: Cytology Source Type: research
Lamellar Inclusions within Hyperplastic Endoplasmic Reticulum in Benign Mesothelial Cells
Conclusion: Cytoplasmic LIs located within hyperplastic rER can be found in up to 14% of effusions restricted to benign mesothelial cells. They can be used as an indirect morphological clue favoring the diagnosis of benign effusion and helping the cytologist to differentiate between reactive and malignant mesothelial cells in daily practice.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - June 29, 2020 Category: Cytology Source Type: research
Downregulation of IL-2 and IL-23 in Cervical Biopsies of Cervical Intraepithelial Lesions: A Cross-Sectional Study
Conclusions: Our study shows that in samples from the lesion site point, 2 important pro-inflammatory cytokines, IL-2 and IL-23, are downregulated in HPV lesions.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - June 29, 2020 Category: Cytology Source Type: research
