The Legacy of a “Cell Whisperer”: Celebrating the Life of Dr. Prabodh Kumar Gupta
Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - February 9, 2021 Category: Cytology Source Type: research
The Application of Fine Needle Aspiration Biopsy in the Diagnosis of Axillary Masses
Conclusion: Our results confirm that FNAB is a valuable initial screening method regarding pathologic diagnosis of axillary mass, in particular with respect to malignancy in 41- to 50-year-old female patients.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - February 3, 2021 Category: Cytology Source Type: research
Accuracy of Subclassification and Grading of Renal Tumors on Fine Needle Aspiration Cytology Alone
Conclusions: Renal tumors are difficult to classify on cytopathology alone. Core needle biopsy and ancillary studies are necessary if diagnosis will change management.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - February 3, 2021 Category: Cytology Source Type: research
Cytological Sub-Classification of Atypia of Undetermined Significance May Predict Malignancy Risk in Thyroid Nodules
Conclusion: The relatively high malignancy rate in our institutions, the suspicious radiographic features, the atypia groups, and the repeat FNA predictive value stratified Bethesda III category nodules for proper malignancy prediction and appropriate management.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - February 1, 2021 Category: Cytology Source Type: research
Cytologic Features of Ventricular Tumors of the Central Nervous System: A Review with Emphasis on Diff-Quik Stained Smears
Background: Neoplasms from the ventricular system share a common location but have highly variable histogenesis. Many are slowly growing tumors that behave in a benign fashion. They can be classified as primary and secondary tumors. The most common primary tumors are ependymomas, subependymomas, subependymal giant cell astrocytomas, central neurocytomas, choroid plexus tumors, meningiomas, germinomas, pineal parenchymal tumors, papillary tumors of the pineal region, chordoid gliomas, rosette-forming glioneuronal tumors of the fourth ventricle, and craniopharyngiomas. Pilocytic astrocytomas, medulloblastomas, and atypical t...
Source: Acta Cytologica - January 21, 2021 Category: Cytology Source Type: research
A Hard Mass of the Right Submandibular Gland in an 83-Yr-Old Lady
Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - January 5, 2021 Category: Cytology Source Type: research
Classification of Male Breast Lesions According to the IAC Yokohama System for Reporting Breast Cytopathology
Conclusion: This study validates the IAC Yokohama System for reporting male breast cytopathology. In accordance with the aim of the Yokohama System to establish best practice guidelines for reporting breast cytopathology, this comprehensive scheme facilitates comparisons between local and international institutions. The ROM acts as an internal audit for quality assurance within one ’s own laboratory and provides guidance for clinical management. It highlights inefficiencies such as high inadequacy rates for category 1 and also features strengths with impressive specificity for categories 4 and 5.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - December 17, 2020 Category: Cytology Source Type: research
Artificial Intelligence in Thyroid Fine Needle Aspiration Biopsies
Background: From cell phones to aerospace, artificial intelligence (AI) has wide-reaching influence in the modern age. In this review, we discuss the application of AI solutions to an equally ubiquitous problem in cytopathology – thyroid fine needle aspiration biopsy (FNAB). Thyroid nodules are common in the general population, and FNAB is the sampling modality of choice. The resulting prevalence in the practicing pathologist’s daily workload makes thyroid FNAB an appealing target for the application of AI solutions.Summary: This review summarizes all available literature on the application of AI to thyroid cytopatholo...
Source: Acta Cytologica - December 16, 2020 Category: Cytology Source Type: research
Role of Cytology in the Current Guidelines for Malignant Mesothelioma: Largest Study from India
Conclusions: Rather than ignoring the role of cytology in the diagnosis and treatment guidelines for MM, it is important to understand its strengths and limitations. Standardized guidelines in future can play an important role in more streamlined communication between cytopathologist and clinician.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - December 14, 2020 Category: Cytology Source Type: research
Outer Cutoff Value for the Box-Counting Method for Fractal Analysis of the Nucleus Using Kirsch Edge Detection
We examined the outer cutoff value for the box-counting (BC) method for fractal analysis of the complexity of chromatin using Kirsch edge detection.Materials: The following images were used for the analysis: (1) image of the nucleus for Kirsch edge detection measuring 97 × 122 pix (10.7 × 13.4 μm) with a Feret diameter of chromatin mesh (n = 50) measuring 17.3 ± 1.8 pix (1.9 ± 0.5 μm) and chromatin network distance (n = 50) measuring 4.4 ± 1.6 pix (0.49 ± 0.18 μm), and (2) sample images for Kirsch edge detection with varying diameters (10.4, 15.9, and 18.1 μm) and network width of 0.4 μm.Methods: Three types of ...
Source: Acta Cytologica - December 10, 2020 Category: Cytology Source Type: research
Evaluation of Elafin Immunohistochemical Expression as Marker of Cervical Cancer Severity
Conclusion: Our results suggest that PI3/Elafin levels and subcellular localization may be used as a biomarker for CC severity.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - December 3, 2020 Category: Cytology Source Type: research
Personalized Medicine and Cervical Screening: Development of Individualized Quantitative Risk Assessments for Cervical Adenocarcinoma and Adenocarcinoma in situ
Conclusion: Prevention of cervical AdCa in screened patients remains a major challenge for cervical screening. Individualized risk projections for cervical glandular neoplasia reflecting patient age, prior cervical screening test results, and prior cervical biopsy history are feasible using Bayesian modeling of health system data.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - December 1, 2020 Category: Cytology Source Type: research
Fine-Needle Aspiration Cytology in Preoperative Diagnosis of Bone Lesions: A Three-Year Study in a Tertiary Care Hospital
Conclusion: We conclude that FNAC is a simple and accurate preoperative diagnostic technique for assessment of bone tumors.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - November 12, 2020 Category: Cytology Source Type: research
Conventional Direct Smear Yields Diagnostic Indicators of Gastric-Type Mucinous Carcinoma Compared with Cytomorphological Features Identified by Liquid-Based Cervical Cytology
Conclusion: This study demonstrated that the diagnostic clues to detect GAS using the conventional approach, namely distinct cell borders and prominent nucleoli, are not useful for excluding UEA in LBC samples. Conventional cervical smears may indicate a diagnosis of GAS; however, specific high-risk HPV detection approaches, such as HPV test or immunocytochemical p16/Ki-67 dual staining, are desirable to differentiate GAS from UEA in the setting of LBC with ambiguous cytomorphological features.Acta Cytologica (Source: Acta Cytologica)
Source: Acta Cytologica - November 11, 2020 Category: Cytology Source Type: research
Recent Advances in Medical Image Processing
Background: Application and development of the artificial intelligence technology have generated a profound impact in the field of medical imaging. It helps medical personnel to make an early and more accurate diagnosis. Recently, the deep convolution neural network is emerging as a principal machine learning method in computer vision and has received significant attention in medical imaging.Key Message: In this paper, we will review recent advances in artificial intelligence, machine learning, and deep convolution neural network, focusing on their applications in medical image processing. To illustrate with a concrete exa...
Source: Acta Cytologica - November 11, 2020 Category: Cytology Source Type: research
