Systematic review and meta-analysis on the effect of adjuvant gonadotropin-releasing hormone agonist (GnRH-a) on pregnancy outcomes in women with endometriosis following conservative surgery
Endometriosis frequently results in pain and infertility. While conservative surgery offers some relief, it often falls short of ensuring satisfactory pregnancy outcomes. Adjuvant GnRH-a is administered post-s... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 4, 2024 Category: OBGYN Authors: Xuemei Qing, Lele He, Ying Ma, Yong Zhang and Wenxin Zheng Tags: Research Source Type: research
Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin
Reprod Biol Endocrinol. 2024 Apr 3;22(1):36. doi: 10.1186/s12958-024-01204-y.ABSTRACTMicrotubule-associated protein 1a (Map1a) is a microtubule (MT) regulatory protein that binds to the MT protofilaments in mammalian cells to promote MT stabilization. Maps work with MT cleavage proteins and other MT catastrophe-inducing proteins to confer MT dynamics to support changes in the Sertoli cell shape to sustain spermatogenesis. However, no functional studies are found in the literature to probe its role in spermatogenesis. Using an RNAi approach, coupled with the use of toxicant-induced testis (in vivo)- and Sertoli cell (in vit...
Source: Reproductive Biology - April 3, 2024 Category: Reproduction Medicine Authors: Lingling Wang Ming Yan Tiao Bu Xiaolong Wu Linxi Li Bruno Silvestrini Fei Sun C Yan Cheng Hao Chen Source Type: research
Gestational and neonatal outcomes of women with partial Dunnigan lipodystrophy
ConclusionOur data showed a high frequency of fetal complications in women with FPLD2. However, no instances of infertility or prolonged attempts to conceive have been reported, highlighting the significance of employing effective contraception strategies to plan pregnancies at optimal times for managing metabolic comorbidities. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - April 3, 2024 Category: Endocrinology Source Type: research
Sexuality and Infertility
This article provides a summary on the relationship between sexuality and infertility and recommendations for the assessment and management of sexual dysfunction in women with infertility. (Source: Obstetrics and Gynecology Clinics)
Source: Obstetrics and Gynecology Clinics - April 3, 2024 Category: OBGYN Authors: Erika L. Kelley, Sheryl A. Kingsberg Source Type: research
Novel SPEF2 variants cause male infertility and likely primary ciliary dyskinesia
ConclusionOur study reported four novel pathogenic variants ofSPEF2 in three male patients with infertility and PCD/PCD-like phenotypes, which not only extend the spectrum ofSPEF2 mutations but also provide information for genetic counseling and treatment of such conditions. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - April 3, 2024 Category: Reproduction Medicine Source Type: research
Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1
CONCLUSIONS: IGF2BP1 exhibits potential beneficial properties in the management of EMs by interacting with PTBP1, thereby highlighting IGF2BP1 as a promising therapeutic target for EMs.PMID:38563050 | DOI:10.5603/fhc.98213 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - April 2, 2024 Category: Cytology Authors: Yanlin Su Wencai Tian Li Cheng Ling Yin Xiaoxia He Xin Wei Source Type: research
Fertility history and intentions of married women, China
CONCLUSION: The willingness of Chinese married women to give birth remained low, even with relaxation of the one-child policy.PMID:38562192 | PMC:PMC10976870 | DOI:10.2471/BLT.23.289736 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Qin Li Rui Yang Zehong Zhou Weiping Qian Jian Zhang Ze Wu Lei Jin Xueqing Wu Cuilian Zhang Beihong Zheng Jichun Tan Guimin Hao Shangwei Li Yongxiu Hao Danni Zheng Yuanyuan Wang Rong Li Ping Liu Jie Qiao Source Type: research
Clinical application value of pre-pregnancy carrier screening in Chinese Han childbearing population
CONCLUSION: Monogenic recessive hereditary diseases had a high carrier rate in the population. Pre-pregnancy screening could provide good prenatal and postnatal care guidance for patients and preimplantation genetic testing for monogenic/single gene disorders (PGT-M) and prenatal diagnosis could provide more precise reproductive choices for high-risk parents.PMID:38562051 | DOI:10.1002/mgg3.2425 (Source: Molecular Medicine)
Source: Molecular Medicine - April 2, 2024 Category: Molecular Biology Authors: Li Tan Yuefan Qi Peijuan Zhao LanLan Cheng Guo Yu Dongmei Zhao Yu Xia Song Yun Gai Xiang Source Type: research
Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1
CONCLUSIONS: IGF2BP1 exhibits potential beneficial properties in the management of EMs by interacting with PTBP1, thereby highlighting IGF2BP1 as a promising therapeutic target for EMs.PMID:38563050 | DOI:10.5603/fhc.98213 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - April 2, 2024 Category: Cytology Authors: Yanlin Su Wencai Tian Li Cheng Ling Yin Xiaoxia He Xin Wei Source Type: research
Fertility history and intentions of married women, China
CONCLUSION: The willingness of Chinese married women to give birth remained low, even with relaxation of the one-child policy.PMID:38562192 | PMC:PMC10976870 | DOI:10.2471/BLT.23.289736 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Qin Li Rui Yang Zehong Zhou Weiping Qian Jian Zhang Ze Wu Lei Jin Xueqing Wu Cuilian Zhang Beihong Zheng Jichun Tan Guimin Hao Shangwei Li Yongxiu Hao Danni Zheng Yuanyuan Wang Rong Li Ping Liu Jie Qiao Source Type: research
Clinical application value of pre-pregnancy carrier screening in Chinese Han childbearing population
CONCLUSION: Monogenic recessive hereditary diseases had a high carrier rate in the population. Pre-pregnancy screening could provide good prenatal and postnatal care guidance for patients and preimplantation genetic testing for monogenic/single gene disorders (PGT-M) and prenatal diagnosis could provide more precise reproductive choices for high-risk parents.PMID:38562051 | PMC:PMC10985407 | DOI:10.1002/mgg3.2425 (Source: Molecular Medicine)
Source: Molecular Medicine - April 2, 2024 Category: Molecular Biology Authors: Li Tan Yuefan Qi Peijuan Zhao LanLan Cheng Guo Yu Dongmei Zhao Yu Xia Song Yun Gai Xiang Source Type: research
Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1
CONCLUSIONS: IGF2BP1 exhibits potential beneficial properties in the management of EMs by interacting with PTBP1, thereby highlighting IGF2BP1 as a promising therapeutic target for EMs.PMID:38563050 | DOI:10.5603/fhc.98213 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - April 2, 2024 Category: Cytology Authors: Yanlin Su Wencai Tian Li Cheng Ling Yin Xiaoxia He Xin Wei Source Type: research
Fertility history and intentions of married women, China
CONCLUSION: The willingness of Chinese married women to give birth remained low, even with relaxation of the one-child policy.PMID:38562192 | PMC:PMC10976870 | DOI:10.2471/BLT.23.289736 (Source: Bulletin of the World Health Organization)
Source: Bulletin of the World Health Organization - April 2, 2024 Category: International Medicine & Public Health Authors: Qin Li Rui Yang Zehong Zhou Weiping Qian Jian Zhang Ze Wu Lei Jin Xueqing Wu Cuilian Zhang Beihong Zheng Jichun Tan Guimin Hao Shangwei Li Yongxiu Hao Danni Zheng Yuanyuan Wang Rong Li Ping Liu Jie Qiao Source Type: research
Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1
CONCLUSIONS: IGF2BP1 exhibits potential beneficial properties in the management of EMs by interacting with PTBP1, thereby highlighting IGF2BP1 as a promising therapeutic target for EMs.PMID:38563050 | DOI:10.5603/fhc.98213 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - April 2, 2024 Category: Cytology Authors: Yanlin Su Wencai Tian Li Cheng Ling Yin Xiaoxia He Xin Wei Source Type: research
