Rare but Still There: A Scoping Review on Endometriosis-Associated Ovarian Cancer
Discov Med. 2024 Mar;36(182):467-481. doi: 10.24976/Discov.Med.202436182.44.ABSTRACTEndometriosis is a medical condition affecting at least up to 10% of women of reproductive age. This condition occurs when ectopic endometrial glands and stroma implant outside the uterus and there are several theories regarding the underlying origins of the disease. Endometriosis is one of the major causes of severe dysmenorrhoea, chronic pelvic pain and infertility. While endometriosis is generally a non-malignant condition, it rarely may transform into an invasive cancer, and increase the risk for epithelial ovarian cancer, notably endom...
Source: Discovery Medicine - March 26, 2024 Category: Research Authors: Karl Livori Jean Calleja-Agius Source Type: research
TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2
CONCLUSION: Our findings revealed a crucial role for CLCA2 in mediating apoptosis in POI pathogenesis, and suggested that CLCA2 is a potential therapeutic target for POI.PMID:38528613 | PMC:PMC10962206 | DOI:10.1186/s13048-024-01396-2 (Source: Cell Research)
Source: Cell Research - March 26, 2024 Category: Cytology Authors: Yali Fan Shuya Chen Chunfang Chu Xiaodan Yin Jing Jin Lingyan Zhang Huihui Yan Zheng Cao Ruixia Liu Mingwei Xin Lin Li Chenghong Yin Source Type: research
Efficacy and safety of follitropin delta versus follitropin alpha/beta in infertility treatment: A systematic review and meta-analysis
CONCLUSION: Follitropin δ may result in little to no difference in COS compared with follitropin α/β, especially in terms of live births and safety.PMID:38528991 | PMC:PMC10961712 | DOI:10.1002/rmb2.12573 (Source: Reproductive Biology)
Source: Reproductive Biology - March 26, 2024 Category: Reproduction Medicine Authors: Shinnosuke Komiya Jun Watanabe Takero Terayama Kyosuke Kamijo Hidetaka Okada Source Type: research
Rare but Still There: A Scoping Review on Endometriosis-Associated Ovarian Cancer
Discov Med. 2024 Mar;36(182):467-481. doi: 10.24976/Discov.Med.202436182.44.ABSTRACTEndometriosis is a medical condition affecting at least up to 10% of women of reproductive age. This condition occurs when ectopic endometrial glands and stroma implant outside the uterus and there are several theories regarding the underlying origins of the disease. Endometriosis is one of the major causes of severe dysmenorrhoea, chronic pelvic pain and infertility. While endometriosis is generally a non-malignant condition, it rarely may transform into an invasive cancer, and increase the risk for epithelial ovarian cancer, notably endom...
Source: Discovery Medicine - March 26, 2024 Category: Research Authors: Karl Livori Jean Calleja-Agius Source Type: research
