Live birth derived from a markedly large polar body oocyte: a rare case report
In this study, it is revealed for the first time that a huge PB1 oocyte can be fertilized, resulting in the growth of a blastocyst, a subsequent pregnancy, and a live birth. This new information prompts us to reconsider the use of large PB1 oocytes. More insightful talks should be given attention to prevent the waste of embryos because not all oocytes with aberrant morphology are unavailable.PMID:38619002 | DOI:10.1017/S0967199424000054 (Source: Zygote)
Source: Zygote - April 15, 2024 Category: Reproduction Medicine Authors: Yongxiang Liu Xinliang Peng Caifeng Liu Shuting Zhang Zhiwei Weng Li Yu Shaohu Zhou Xuekun Huang Source Type: research
A New Model Including AMH Cut-off Levels to Predict Post-treatment Ovarian Function in Early Breast Cancer: A Prospective Cohort Study
CONCLUSION: This combination model can be used to withhold fertility preservation procedures in BC patients. Performing larger studies is suggested to further test this model.PMID:38619033 | DOI:10.34172/aim.2024.15 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - April 15, 2024 Category: Middle East Health Authors: Ramesh Omranipour Fatemeh Ahmadi-Harchegani Azin Saberi Ashraf Moini Mostafa Shiri Amirmohsen Jalaeefar Arvin Arian Akram Seifollahi Mahshad Madani Bita Eslami Sadaf Alipour Source Type: research
In Vitro Fertilization Practice in Patients with Absolute Uterine Factor Undergoing Uterus Transplant in the United States
Capsule: Live birth rates per embryo transfer after uterus transplant are favorable and comparable to individuals using assisted reproduction with other causes of infertility. (Source: Fertility and Sterility)
Source: Fertility and Sterility - April 15, 2024 Category: Reproduction Medicine Authors: Jessica R. WALTER, Liza JOHANNESSON, Tommaso FALCONE, J. Michael PUTNAM, Giuliano TESTA, Elliott G. RICHARDS, Kathleen E. O ’NEILL Tags: Assisted reproduction Source Type: research
Cancer risk and male Infertility: Unravelling predictive biomarkers and prognostic indicators
Clin Chim Acta. 2024 Apr 11:119670. doi: 10.1016/j.cca.2024.119670. Online ahead of print.ABSTRACTIn recent years, there has been a global increase in cases of male infertility. There are about 30 million cases of male infertility worldwide and male reproductive health is showing rapid decline in last few decades. It is now recognized as a potential risk factor for developing certain types of cancer, particularly genitourinary malignancies like testicular and prostate cancer. Male infertility is considered a potential indicator of overall health and an early biomarker for cancer. Cases of unexplained male factor infertilit...
Source: International Journal of Clinical Chemistry - April 13, 2024 Category: Chemistry Authors: Prabhakar Tiwari Anjali Yadav Meenakshi Kaushik Rima Dada Source Type: research
Age-related increase in live-birth rates of first frozen thaw embryo versus first fresh transfer in initial assisted reproductive technology cycles without PGT
CONCLUSIONS: Overall LBR and CLBR were greater for first FET than fresh transfers with incremental increases in odds of live birth with advancing age, suggesting the presence of a more favorable age-related change in endometrial receptivity present in frozen-thawed cycles. For both DOR and MF cycles, LBR and CLBR after primary transfer were greater for first FET than fresh. However, this was particularly evident in older ages for DOR cycles. This suggests that supraphysiologic stimulation in older DOR cycles may be detrimental to endometrial receptivity, which is in part corrected for in FET cycles.PMID:38615016 | DOI:10.1...
Source: Reproductive Biology - April 13, 2024 Category: Reproduction Medicine Authors: Sarah F Wang David B Seifer Source Type: research
Cancer risk and male Infertility: Unravelling predictive biomarkers and prognostic indicators
Clin Chim Acta. 2024 Apr 11:119670. doi: 10.1016/j.cca.2024.119670. Online ahead of print.ABSTRACTIn recent years, there has been a global increase in cases of male infertility. There are about 30 million cases of male infertility worldwide and male reproductive health is showing rapid decline in last few decades. It is now recognized as a potential risk factor for developing certain types of cancer, particularly genitourinary malignancies like testicular and prostate cancer. Male infertility is considered a potential indicator of overall health and an early biomarker for cancer. Cases of unexplained male factor infertilit...
Source: International Journal of Clinical Chemistry - April 13, 2024 Category: Chemistry Authors: Prabhakar Tiwari Anjali Yadav Meenakshi Kaushik Rima Dada Source Type: research
Cancer risk and male Infertility: Unravelling predictive biomarkers and prognostic indicators
Clin Chim Acta. 2024 Apr 11:119670. doi: 10.1016/j.cca.2024.119670. Online ahead of print.ABSTRACTIn recent years, there has been a global increase in cases of male infertility. There are about 30 million cases of male infertility worldwide and male reproductive health is showing rapid decline in last few decades. It is now recognized as a potential risk factor for developing certain types of cancer, particularly genitourinary malignancies like testicular and prostate cancer. Male infertility is considered a potential indicator of overall health and an early biomarker for cancer. Cases of unexplained male factor infertilit...
Source: Clinical Prostate Cancer - April 13, 2024 Category: Cancer & Oncology Authors: Prabhakar Tiwari Anjali Yadav Meenakshi Kaushik Rima Dada Source Type: research
Age-related increase in live-birth rates of first frozen thaw embryo versus first fresh transfer in initial assisted reproductive technology cycles without PGT
CONCLUSIONS: Overall LBR and CLBR were greater for first FET than fresh transfers with incremental increases in odds of live birth with advancing age, suggesting the presence of a more favorable age-related change in endometrial receptivity present in frozen-thawed cycles. For both DOR and MF cycles, LBR and CLBR after primary transfer were greater for first FET than fresh. However, this was particularly evident in older ages for DOR cycles. This suggests that supraphysiologic stimulation in older DOR cycles may be detrimental to endometrial receptivity, which is in part corrected for in FET cycles.PMID:38615016 | PMC:PMC1...
Source: Reproductive Biology - April 13, 2024 Category: Reproduction Medicine Authors: Sarah F Wang David B Seifer Source Type: research
Infertile Jordanian Women ’s Self-Perception About Societal Violence: An Interpretative Phenomenological Study
(Source: International Journal of Womens Health)
Source: International Journal of Womens Health - April 13, 2024 Category: OBGYN Tags: International Journal of Women's Health Source Type: research
IJERPH, Vol. 21, Pages 475: Addressing the Rehabilitation Needs of Women Experiencing Infertility in Ethiopia: Time for Action
In conclusion, it is essential to strengthen the policies around infertility, incorporate rehabilitation services in fertility care, and view infertility as a disabling condition for women who experience it in Ethiopia. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - April 13, 2024 Category: Environmental Health Authors: Bilen Mekonnen Araya Maria P. Velez Kassahun Alemu Gelaye Silke Dyer Heather M. Aldersey Tags: Article Source Type: research
Commonality and heterogeneity of pacemaker mechanisms in the male reproductive organs
J Physiol. 2024 Apr 12. doi: 10.1113/JP284756. Online ahead of print.ABSTRACTDuring emission, the first phase of ejaculation, smooth muscle in organs of the male reproductive tract (MRT) vigorously contract upon sympathetic nerve excitation to expel semen consisting of sperm and seminal plasma. During inter-ejaculation phases, the epididymis, seminal vesicles and prostate undergo spontaneous phasic contractions (SPCs), this transporting and maintaining the quality of sperm and seminal plasma. Recent studies have revealed platelet-derived growth factor receptor α-expressing (PDGFRα+) subepithelial interstitial cells in se...
Source: The Journal of Physiology - April 12, 2024 Category: Physiology Authors: Hikaru Hashitani Mitsue Takeya Dirk F van Helden Source Type: research
LncRNA XIST Protects Against Polycystic Ovary Syndrome via the Regulation of miR-212-3p/RASA1 Axis
Biochem Genet. 2024 Apr 12. doi: 10.1007/s10528-024-10777-7. Online ahead of print.ABSTRACTThe polycystic ovary syndrome (PCOS), a common endocrine disorder, is mainly related to infertility. Moreover, it is characterized by promoted androgen, suppressed ovulation and insulin resistance. Long non-coding RNA X inactive specific transcript (lncRNA XIST), known as an oncogene or a cancer inhabited factor, is involved in several disease. However, the diagnostic mechanisms of lncRNA XIST in PCOS have not been clarified. Our study aimed to explain whether lncRNA XIST regulates KGN cells proliferation and apoptosis via microRNA (...
Source: Biochemical Genetics - April 12, 2024 Category: Genetics & Stem Cells Authors: Xiaomeng Xu Cheng Yin Bing Dong Yuewen Li Shi Liu Jun Chen Source Type: research
Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease †
In this study, we review the underlying principles of shear wave elastography and its current clinical uses outside the reproductive tract as well as its successful application of shear wave elastography to reproductive tissues, including the uterus and cervix. We also describe an emerging use of this technology in evaluation of human ovarian stiffness via transvaginal ultrasound. Establishing ovarian stiffness as a clinical biomarker of ovarian aging may have implications for predicting the ovarian reserve and outcomes of Assisted Reproductive Technologies as well as for the assessment of the efficacy of emerging therapeu...
Source: Biology of Reproduction - April 12, 2024 Category: Reproduction Medicine Authors: Emily J Zaniker Man Zhang Lydia Hughes Lizellen La Follette Tomiris Atazhanova Alexis Trofimchuk Elnur Babayev Francesca E Duncan Source Type: research
Exposure to toxicologically relevant atrazine concentrations impair the glycolytic function of mouse Sertoli cells through the downregulation of lactate dehydrogenase
Toxicol Appl Pharmacol. 2024 Apr 10:116929. doi: 10.1016/j.taap.2024.116929. Online ahead of print.ABSTRACTAtrazine (ATZ), a widely used herbicide with potent endocrine-disrupting properties, has been implicated in hormonal disturbances and fertility issues. Sertoli cells (SCs) play a crucial role in providing mechanical and nutritional support of spermatogenesis. Herein, we aimed to study the effects of environmentally relevant ATZ concentrations on the nutritional support of spermatogenesis provided by SCs. For that, mouse SCs (TM4) were exposed to increasing ATZ concentrations (in μg/L: 0.3, 3, 30, 300, or 3000). After...
Source: Toxicology and Applied Pharmacology - April 12, 2024 Category: Toxicology Authors: Daniela Gomes-Andrade B árbara Guerra-Carvalho David F Carrageta Raquel L Bernardino Patr ícia C Braga Pedro F Oliveira Maria de Lourdes Pereira Marco G Alves Source Type: research
Shear wave elastography to assess stiffness of the human ovary and other reproductive tissues across the reproductive lifespan in health and disease †
In this study, we review the underlying principles of shear wave elastography and its current clinical uses outside the reproductive tract as well as its successful application of shear wave elastography to reproductive tissues, including the uterus and cervix. We also describe an emerging use of this technology in evaluation of human ovarian stiffness via transvaginal ultrasound. Establishing ovarian stiffness as a clinical biomarker of ovarian aging may have implications for predicting the ovarian reserve and outcomes of Assisted Reproductive Technologies as well as for the assessment of the efficacy of emerging therapeu...
Source: Reproductive Biology - April 12, 2024 Category: Reproduction Medicine Authors: Emily J Zaniker Man Zhang Lydia Hughes Lizellen La Follette Tomiris Atazhanova Alexis Trofimchuk Elnur Babayev Francesca E Duncan Source Type: research
