A chronic moderate methionine administration induced hyperhomocysteinemia associated with cardiovascular disease phenotype in the sand rat Psammomys obesus
CONCLUSIONS: Our results show for the first time that Hhcy can induce a cardiovascular and liver diseases phenotype in Psammomys obesus, a species previously shown to be a good model for the studies of diabetes and other metabolism-related pathologies.PMID:35603572 | DOI:10.5603/FHC.a2022.0013 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 23, 2022 Category: Cytology Authors: Fouzia Zerrouk Billel Chaouad Adel Ghoul Naima Chalour Anissa Moulahoum Zineb Khiari Mohamed El Hadi Cherifi Souhila Aouichat Karim Houali Yasmina Benazzoug Source Type: research

GLI1 is involved in HIF-1 α-induced migration, invasion, and epithelial-mesenchymal transition in glioma cells
CONCLUSIONS: GLI1 is involved in HIF-1α-induced migration, invasion, and EMT in glioma cells, thus revealing a novel molecular mechanism for glioma research.PMID:35603730 | DOI:10.5603/FHC.a2022.0014 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 23, 2022 Category: Cytology Authors: Yihai Lin Liang Guo Source Type: research

A chronic moderate methionine administration induced hyperhomocysteinemia associated with cardiovascular disease phenotype in the sand rat Psammomys obesus
CONCLUSIONS: Our results show for the first time that Hhcy can induce a cardiovascular and liver diseases phenotype in Psammomys obesus, a species previously shown to be a good model for the studies of diabetes and other metabolism-related pathologies.PMID:35603572 | DOI:10.5603/FHC.a2022.0013 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 23, 2022 Category: Cytology Authors: Fouzia Zerrouk Billel Chaouad Adel Ghoul Naima Chalour Anissa Moulahoum Zineb Khiari Mohamed El Hadi Cherifi Souhila Aouichat Karim Houali Yasmina Benazzoug Source Type: research

GLI1 is involved in HIF-1 α-induced migration, invasion, and epithelial-mesenchymal transition in glioma cells
CONCLUSIONS: GLI1 is involved in HIF-1α-induced migration, invasion, and EMT in glioma cells, thus revealing a novel molecular mechanism for glioma research.PMID:35603730 | DOI:10.5603/FHC.a2022.0014 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 23, 2022 Category: Cytology Authors: Yihai Lin Liang Guo Source Type: research

A chronic moderate methionine administration induced hyperhomocysteinemia associated with cardiovascular disease phenotype in the sand rat Psammomys obesus
CONCLUSIONS: Our results show for the first time that Hhcy can induce a cardiovascular and liver diseases phenotype in Psammomys obesus, a species previously shown to be a good model for the studies of diabetes and other metabolism-related pathologies.PMID:35603572 | DOI:10.5603/FHC.a2022.0013 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 23, 2022 Category: Cytology Authors: Fouzia Zerrouk Billel Chaouad Adel Ghoul Naima Chalour Anissa Moulahoum Zineb Khiari Mohamed El Hadi Cherifi Souhila Aouichat Karim Houali Yasmina Benazzoug Source Type: research

GLI1 is involved in HIF-1 α-induced migration, invasion, and epithelial-mesenchymal transition in glioma cells
CONCLUSIONS: GLI1 is involved in HIF-1α-induced migration, invasion, and EMT in glioma cells, thus revealing a novel molecular mechanism for glioma research.PMID:35603730 | DOI:10.5603/FHC.a2022.0014 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 23, 2022 Category: Cytology Authors: Yihai Lin Liang Guo Source Type: research

Extracts of Periplaneta americana alleviate hepatic fibrosis by affecting hepatic TGF- β and NF-κB expression in rats with pig serum-induced liver fibrosis
CONCLUSIONS: We found that EPA could reduce liver inflammation, suppress liver cell degeneration and necrosis, and reduce the formation of liver fibrous tissue. Its mechanism might be associated with inhibiting the expression of TGF-β1, TIMP-1, NF-κB and α-SMA to block signal transduction pathways in the hepatic fibrosis process. Therefore, EPA, as a traditional Chinese medicine, might be potentially used to prevent and treat hepatic fibrosis in the future. However, further more experiments are necessary to verify its effectiveness and possible signaling pathways.PMID:35575220 | DOI:10.5603/FHC.a2022.0011 (Source: Folia...
Source: Folia Histochemica et Cytobiologica - May 16, 2022 Category: Cytology Authors: Dingchun Li Dehong Ma Ye Liu Lihui Liu Yihui Chen Huaie Liu Lu Zhang Jie Lu Kexuan Chen Wu Li Jing You Source Type: research

Identification of candidate genes simultaneously shared by adipogenesis and osteoblastogenesis from human mesenchymal stem cells
CONCLUSION: This study would provide the potential molecular switches to control the adipocyte/osteoblastocyte balance or hMSCs fate choices and clues to screen the study and therapy targets of metabolic bone disease osteoporosis.PMID:35575247 | DOI:10.5603/FHC.a2022.0012 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 16, 2022 Category: Cytology Authors: Xia Yi Ping Wu Yunyan Fan Ying Gong Jianyun Liu Jianjun Xiong Xiaoyun Xu Source Type: research

Extracts of Periplaneta americana alleviate hepatic fibrosis by affecting hepatic TGF- β and NF-κB expression in rats with pig serum-induced liver fibrosis
CONCLUSIONS: We found that EPA could reduce liver inflammation, suppress liver cell degeneration and necrosis, and reduce the formation of liver fibrous tissue. Its mechanism might be associated with inhibiting the expression of TGF-β1, TIMP-1, NF-κB and α-SMA to block signal transduction pathways in the hepatic fibrosis process. Therefore, EPA, as a traditional Chinese medicine, might be potentially used to prevent and treat hepatic fibrosis in the future. However, further more experiments are necessary to verify its effectiveness and possible signaling pathways.PMID:35575220 | DOI:10.5603/FHC.a2022.0011 (Source: Folia...
Source: Folia Histochemica et Cytobiologica - May 16, 2022 Category: Cytology Authors: Dingchun Li Dehong Ma Ye Liu Lihui Liu Yihui Chen Huaie Liu Lu Zhang Jie Lu Kexuan Chen Wu Li Jing You Source Type: research

Identification of candidate genes simultaneously shared by adipogenesis and osteoblastogenesis from human mesenchymal stem cells
CONCLUSION: This study would provide the potential molecular switches to control the adipocyte/osteoblastocyte balance or hMSCs fate choices and clues to screen the study and therapy targets of metabolic bone disease osteoporosis.PMID:35575247 | DOI:10.5603/FHC.a2022.0012 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 16, 2022 Category: Cytology Authors: Xia Yi Ping Wu Yunyan Fan Ying Gong Jianyun Liu Jianjun Xiong Xiaoyun Xu Source Type: research

Extracts of Periplaneta americana alleviate hepatic fibrosis by affecting hepatic TGF- β and NF-κB expression in rats with pig serum-induced liver fibrosis
CONCLUSIONS: We found that EPA could reduce liver inflammation, suppress liver cell degeneration and necrosis, and reduce the formation of liver fibrous tissue. Its mechanism might be associated with inhibiting the expression of TGF-β1, TIMP-1, NF-κB and α-SMA to block signal transduction pathways in the hepatic fibrosis process. Therefore, EPA, as a traditional Chinese medicine, might be potentially used to prevent and treat hepatic fibrosis in the future. However, further more experiments are necessary to verify its effectiveness and possible signaling pathways.PMID:35575220 | DOI:10.5603/FHC.a2022.0011 (Source: Folia...
Source: Folia Histochemica et Cytobiologica - May 16, 2022 Category: Cytology Authors: Dingchun Li Dehong Ma Ye Liu Lihui Liu Yihui Chen Huaie Liu Lu Zhang Jie Lu Kexuan Chen Wu Li Jing You Source Type: research

Identification of candidate genes simultaneously shared by adipogenesis and osteoblastogenesis from human mesenchymal stem cells
CONCLUSION: This study would provide the potential molecular switches to control the adipocyte/osteoblastocyte balance or hMSCs fate choices and clues to screen the study and therapy targets of metabolic bone disease osteoporosis.PMID:35575247 | DOI:10.5603/FHC.a2022.0012 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 16, 2022 Category: Cytology Authors: Xia Yi Ping Wu Yunyan Fan Ying Gong Jianyun Liu Jianjun Xiong Xiaoyun Xu Source Type: research

Extracts of Periplaneta americana alleviate hepatic fibrosis by affecting hepatic TGF- β and NF-κB expression in rats with pig serum-induced liver fibrosis
CONCLUSIONS: We found that EPA could reduce liver inflammation, suppress liver cell degeneration and necrosis, and reduce the formation of liver fibrous tissue. Its mechanism might be associated with inhibiting the expression of TGF-β1, TIMP-1, NF-κB and α-SMA to block signal transduction pathways in the hepatic fibrosis process. Therefore, EPA, as a traditional Chinese medicine, might be potentially used to prevent and treat hepatic fibrosis in the future. However, further more experiments are necessary to verify its effectiveness and possible signaling pathways.PMID:35575220 | DOI:10.5603/FHC.a2022.0011 (Source: Folia...
Source: Folia Histochemica et Cytobiologica - May 16, 2022 Category: Cytology Authors: Dingchun Li Dehong Ma Ye Liu Lihui Liu Yihui Chen Huaie Liu Lu Zhang Jie Lu Kexuan Chen Wu Li Jing You Source Type: research

Identification of candidate genes simultaneously shared by adipogenesis and osteoblastogenesis from human mesenchymal stem cells
CONCLUSION: This study would provide the potential molecular switches to control the adipocyte/osteoblastocyte balance or hMSCs fate choices and clues to screen the study and therapy targets of metabolic bone disease osteoporosis.PMID:35575247 | DOI:10.5603/FHC.a2022.0012 (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - May 16, 2022 Category: Cytology Authors: Xia Yi Ping Wu Yunyan Fan Ying Gong Jianyun Liu Jianjun Xiong Xiaoyun Xu Source Type: research

Extracts of Periplaneta americana alleviate hepatic fibrosis by affecting hepatic TGF- β and NF-κB expression in rats with pig serum-induced liver fibrosis
CONCLUSIONS: We found that EPA could reduce liver inflammation, suppress liver cell degeneration and necrosis, and reduce the formation of liver fibrous tissue. Its mechanism might be associated with inhibiting the expression of TGF-β1, TIMP-1, NF-κB and α-SMA to block signal transduction pathways in the hepatic fibrosis process. Therefore, EPA, as a traditional Chinese medicine, might be potentially used to prevent and treat hepatic fibrosis in the future. However, further more experiments are necessary to verify its effectiveness and possible signaling pathways.PMID:35575220 | DOI:10.5603/FHC.a2022.0011 (Source: Folia...
Source: Folia Histochemica et Cytobiologica - May 16, 2022 Category: Cytology Authors: Dingchun Li Dehong Ma Ye Liu Lihui Liu Yihui Chen Huaie Liu Lu Zhang Jie Lu Kexuan Chen Wu Li Jing You Source Type: research