Testicular sperm retrieval for intracytoplasmic sperm injection: when to consider it after unsuccessful intracytoplasmic sperm injection with ejaculated sperm?
ConclusionsTMS and DFI were found to be significant predictors of live birth outcomes in couples with oligozoospermic male partners undergoing T-ICSI. These findings may help clinicians tailor treatment strategies for this specific patient population. (Source: Andrology)
Source: Andrology - April 2, 2024 Category: Urology & Nephrology Authors: Muhammed Arif Ibis, Eda Ureyen Ozdemir, Khaled Obaid, Cagri Akpinar, Batuhan Ozmen, Kaan Aydos, Onder Yaman Tags: ORIGINAL ARTICLE Source Type: research

Clinical application value of pre ‐pregnancy carrier screening in Chinese Han childbearing population
ConclusionMonogenic recessive hereditary diseases had a high carrier rate in the population. Pre-pregnancy screening could provide good prenatal and postnatal care guidance for patients and preimplantation genetic testing for monogenic/single gene disorders (PGT-M) and prenatal diagnosis could provide more precise reproductive choices for high-risk parents. (Source: Molecular Genetics & Genomic Medicine)
Source: Molecular Genetics & Genomic Medicine - April 2, 2024 Category: Genetics & Stem Cells Authors: Li Tan, Yuefan Qi, Peijuan Zhao, LanLan Cheng, Guo Yu, Dongmei Zhao, Yu Xia Song, Yun Gai Xiang Tags: ORIGINAL ARTICLE Source Type: research

Assessment of quality of life, psychological aspects, and sexual function of women with endometriosis according to pain and infertility: a cross sectional study
ConclusionPain symptoms worsen anxiety, depression, and quality of life of women with endometriosis and when associated with infertility, greater impairment of psychological aspects may occur. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 2, 2024 Category: OBGYN Source Type: research

The impact of a second embryo biopsy for preimplantation genetic testing for monogenic diseases (PGT-M) with inconclusive results on pregnancy potential: results from a matched case –control study
ConclusionsThe re-biopsy intervention seems to considerably reduce the pregnancy potential of a blastocyst. However, a greater sample size is necessary to clarify this issue definitively. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - April 1, 2024 Category: Reproduction Medicine Source Type: research

Various repair events following CRISPR/Cas9-based mutational correction of an infertility-related mutation in mouse embryos
ConclusionOur results suggest the occurrence of mosaicism and complex repair events after CRISPR/Cas9 DSB induction where chromosomal integrity is predominantly contained. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - April 1, 2024 Category: Reproduction Medicine Source Type: research

103. Plasma Anti-M üllerian Hormone Concentrations in Adolescents and Young Adults with Endometriosis
We examined AMH levels in adolescents and young adults (AYA; (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Emma Singleton, Allison Vitonis, Ashley Laliberte, Amy Shafrir, Stacey Missmer, Kathryn Terry, Amy DiVasta Source Type: research

50. Evaluation of an educational video assessing knowledge and attitudes of transgender youth on fertility preservation
This study assessed: (1)The understandability, actionability, and readability of the FP educational videos; (2)Patient perceptions, knowledge, barriers, and interest in FP; and (3) Overall satisfaction with patient education videos on FP (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 1, 2024 Category: OBGYN Authors: Florence Gr égoire-Briard, Andie Chernoff, Ken Tang, Jenna Gale, Margaret L. Lawson, Maria Kielly Source Type: research

The impact of a second embryo biopsy for preimplantation genetic testing for monogenic diseases (PGT-M) with inconclusive results on pregnancy potential: results from a matched case –control study
ConclusionsThe re-biopsy intervention seems to considerably reduce the pregnancy potential of a blastocyst. However, a greater sample size is necessary to clarify this issue definitively. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - April 1, 2024 Category: Reproduction Medicine Source Type: research

Various repair events following CRISPR/Cas9-based mutational correction of an infertility-related mutation in mouse embryos
ConclusionOur results suggest the occurrence of mosaicism and complex repair events after CRISPR/Cas9 DSB induction where chromosomal integrity is predominantly contained. (Source: Journal of Assisted Reproduction and Genetics)
Source: Journal of Assisted Reproduction and Genetics - April 1, 2024 Category: Reproduction Medicine Source Type: research

Cytokine and chemokine profiles in women with endometriosis, polycystic ovary syndrome, and unexplained infertility
Cytokine. 2024 Mar 30;178:156588. doi: 10.1016/j.cyto.2024.156588. Online ahead of print.ABSTRACTNumerous factors (including immunological, congenital, hormonal, and morphological disorders) can lead to infertility. In this regard, 3 specific diseases associated with infertility are discussed in this review study (i.e., polycystic ovary syndrome [PCOS], endometriosis [EMS], and unexplained infertility [UI]). PCOS is a common endocrine disorder characterized by chronic low-grade inflammation, and EMS is a benign disease characterized by the presence of ectopic endometrial tissue. UI refers to couples who are unable to conce...
Source: Cytokine - March 31, 2024 Category: Molecular Biology Authors: Alireza Omidvar-Mehrabadi Fateme Ebrahimi Mehdi Shahbazi Mousa Mohammadnia-Afrouzi Source Type: research

Cytokine and chemokine profiles in women with endometriosis, polycystic ovary syndrome, and unexplained infertility
Cytokine. 2024 Mar 30;178:156588. doi: 10.1016/j.cyto.2024.156588. Online ahead of print.ABSTRACTNumerous factors (including immunological, congenital, hormonal, and morphological disorders) can lead to infertility. In this regard, 3 specific diseases associated with infertility are discussed in this review study (i.e., polycystic ovary syndrome [PCOS], endometriosis [EMS], and unexplained infertility [UI]). PCOS is a common endocrine disorder characterized by chronic low-grade inflammation, and EMS is a benign disease characterized by the presence of ectopic endometrial tissue. UI refers to couples who are unable to conce...
Source: Cytokine - March 31, 2024 Category: Molecular Biology Authors: Alireza Omidvar-Mehrabadi Fateme Ebrahimi Mehdi Shahbazi Mousa Mohammadnia-Afrouzi Source Type: research

Cytokine and chemokine profiles in women with endometriosis, polycystic ovary syndrome, and unexplained infertility
Cytokine. 2024 Mar 30;178:156588. doi: 10.1016/j.cyto.2024.156588. Online ahead of print.ABSTRACTNumerous factors (including immunological, congenital, hormonal, and morphological disorders) can lead to infertility. In this regard, 3 specific diseases associated with infertility are discussed in this review study (i.e., polycystic ovary syndrome [PCOS], endometriosis [EMS], and unexplained infertility [UI]). PCOS is a common endocrine disorder characterized by chronic low-grade inflammation, and EMS is a benign disease characterized by the presence of ectopic endometrial tissue. UI refers to couples who are unable to conce...
Source: Cytokine - March 31, 2024 Category: Molecular Biology Authors: Alireza Omidvar-Mehrabadi Fateme Ebrahimi Mehdi Shahbazi Mousa Mohammadnia-Afrouzi Source Type: research

Cytokine and chemokine profiles in women with endometriosis, polycystic ovary syndrome, and unexplained infertility
Cytokine. 2024 Mar 30;178:156588. doi: 10.1016/j.cyto.2024.156588. Online ahead of print.ABSTRACTNumerous factors (including immunological, congenital, hormonal, and morphological disorders) can lead to infertility. In this regard, 3 specific diseases associated with infertility are discussed in this review study (i.e., polycystic ovary syndrome [PCOS], endometriosis [EMS], and unexplained infertility [UI]). PCOS is a common endocrine disorder characterized by chronic low-grade inflammation, and EMS is a benign disease characterized by the presence of ectopic endometrial tissue. UI refers to couples who are unable to conce...
Source: Cytokine - March 31, 2024 Category: Molecular Biology Authors: Alireza Omidvar-Mehrabadi Fateme Ebrahimi Mehdi Shahbazi Mousa Mohammadnia-Afrouzi Source Type: research

GSE252198 Nanopore-based full-length transcriptome sequencing of yak (Bos grunniens) testis
Contributors : Xingdong Wang ; Shaoke Guo ; Jie Pei ; Xian GuoSeries Type : Expression profiling by high throughput sequencingOrganism : Bos grunniens ; Bos grunniens x Bos taurusAlternative splicing (AS) is strictly regulated during cell differentiation and development. AS events are common in the testis, but the splicing regulation in spermatogenesis is still unclear. In this experiment, the third-generation ONT sequencing was used to sequence the full-length transcriptome of testicular tissue, and 40,038 new transcripts were obtained, and the proportion was almost close to the number of known transcripts identified....
Source: GEO: Gene Expression Omnibus - March 31, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Bos grunniens Bos grunniens x Bos taurus Source Type: research