Why efforts to make better, more universal coronavirus vaccines are struggling
There’s a new call from the White House to develop vaccines that might protect against future SARS-CoV-2 mutants or even unknown coronaviruses. “The vaccines we have are terrific, but we can do better than terrific,” Ashish Jha, White House COVID-19 response coordinator, said at a vaccine summit yesterday that gathered researchers, companies, and government officials. “Ultimately, we need vaccines that can protect us no matter what Mother Nature throws at us.” But no specific funding request to Congress was revealed at the summit, or any concrete plans, so vaccine developers and the public shouldn’t expec...
Source: Science of Aging Knowledge Environment - July 27, 2022 Category: Geriatrics Source Type: research

Risk Factors and Treatments of Suprachoroidal Hemorrhage
Biomed Res Int. 2022 Jul 14;2022:6539917. doi: 10.1155/2022/6539917. eCollection 2022.ABSTRACTSuprachoroidal hemorrhage (SCH) is a rare but serious sight-threatening complication of inner eye surgery. Despite continuous advances in treatment, visual prognosis remains poor. The disease has a more typical clinical presentation, the etiology and pathogenesis are not well defined, and intraoperative ocular and systemic factors may induce fulminant SCH. To investigate risk factors and treatments of SCH-associated intraocular surgeries, summarize diagnosis, characteristics, management, and prevention of SCH developed during and ...
Source: Biomed Res - July 25, 2022 Category: Research Authors: Huaiyan Jiang Yang Gao Wenzhong Fu Hongxia Xu Source Type: research

Risk Factors and Treatments of Suprachoroidal Hemorrhage
Biomed Res Int. 2022 Jul 14;2022:6539917. doi: 10.1155/2022/6539917. eCollection 2022.ABSTRACTSuprachoroidal hemorrhage (SCH) is a rare but serious sight-threatening complication of inner eye surgery. Despite continuous advances in treatment, visual prognosis remains poor. The disease has a more typical clinical presentation, the etiology and pathogenesis are not well defined, and intraoperative ocular and systemic factors may induce fulminant SCH. To investigate risk factors and treatments of SCH-associated intraocular surgeries, summarize diagnosis, characteristics, management, and prevention of SCH developed during and ...
Source: Biomed Res - July 25, 2022 Category: Research Authors: Huaiyan Jiang Yang Gao Wenzhong Fu Hongxia Xu Source Type: research

Sensors, Vol. 22, Pages 5522: Reliable Aerial Mobile Communications with RSRP & amp; RSRQ Prediction Models for the Internet of Drones: A Machine Learning Approach
Sensors, Vol. 22, Pages 5522: Reliable Aerial Mobile Communications with RSRP & RSRQ Prediction Models for the Internet of Drones: A Machine Learning Approach Sensors doi: 10.3390/s22155522 Authors: Mehran Behjati Muhammad Aidiel Zulkifley Haider A. H. Alobaidy Rosdiadee Nordin Nor Fadzilah Abdullah The unmanned aerial vehicle (UAV) industry is moving toward beyond visual line of sight (BVLOS) operations to unlock future internet of drones applications, including unmanned environmental monitoring and long-range delivery services. A reliable and ubiquitous mobile communication link plays a vital role...
Source: Sensors - July 24, 2022 Category: Biotechnology Authors: Mehran Behjati Muhammad Aidiel Zulkifley Haider A. H. Alobaidy Rosdiadee Nordin Nor Fadzilah Abdullah Tags: Article Source Type: research

A novel montmorillonite clay-cetylpyridinium chloride complex as a potential antiamoebic composite material in contact lenses disinfection
CONCLUSION: Given the ease of usage, safety, cost-effectiveness and long-term stability, CPC and CPC-Mt complex can prove to be an excellent choice in the rational development of contact-lens disinfectants to eradicate pathogenic Acanthamoeba effectively.PMID:35868573 | DOI:10.1016/j.exppara.2022.108330 (Source: Experimental Parasitology)
Source: Experimental Parasitology - July 22, 2022 Category: Parasitology Authors: Noor Akbar Ruqaiyyah Siddiqui Mustafa Khamis Taleb Ibrahim Naveed Ahmed Khan Source Type: research

A novel montmorillonite clay-cetylpyridinium chloride complex as a potential antiamoebic composite material in contact lenses disinfection
CONCLUSION: Given the ease of usage, safety, cost-effectiveness and long-term stability, CPC and CPC-Mt complex can prove to be an excellent choice in the rational development of contact-lens disinfectants to eradicate pathogenic Acanthamoeba effectively.PMID:35868573 | DOI:10.1016/j.exppara.2022.108330 (Source: Experimental Parasitology)
Source: Experimental Parasitology - July 22, 2022 Category: Parasitology Authors: Noor Akbar Ruqaiyyah Siddiqui Mustafa Khamis Taleb Ibrahim Naveed Ahmed Khan Source Type: research

A novel montmorillonite clay-cetylpyridinium chloride complex as a potential antiamoebic composite material in contact lenses disinfection
CONCLUSION: Given the ease of usage, safety, cost-effectiveness and long-term stability, CPC and CPC-Mt complex can prove to be an excellent choice in the rational development of contact-lens disinfectants to eradicate pathogenic Acanthamoeba effectively.PMID:35868573 | DOI:10.1016/j.exppara.2022.108330 (Source: Experimental Parasitology)
Source: Experimental Parasitology - July 22, 2022 Category: Parasitology Authors: Noor Akbar Ruqaiyyah Siddiqui Mustafa Khamis Taleb Ibrahim Naveed Ahmed Khan Source Type: research

A novel montmorillonite clay-cetylpyridinium chloride complex as a potential antiamoebic composite material in contact lenses disinfection
CONCLUSION: Given the ease of usage, safety, cost-effectiveness and long-term stability, CPC and CPC-Mt complex can prove to be an excellent choice in the rational development of contact-lens disinfectants to eradicate pathogenic Acanthamoeba effectively.PMID:35868573 | DOI:10.1016/j.exppara.2022.108330 (Source: Experimental Parasitology)
Source: Experimental Parasitology - July 22, 2022 Category: Parasitology Authors: Noor Akbar Ruqaiyyah Siddiqui Mustafa Khamis Taleb Ibrahim Naveed Ahmed Khan Source Type: research

A novel montmorillonite clay-cetylpyridinium chloride complex as a potential antiamoebic composite material in contact lenses disinfection
CONCLUSION: Given the ease of usage, safety, cost-effectiveness and long-term stability, CPC and CPC-Mt complex can prove to be an excellent choice in the rational development of contact-lens disinfectants to eradicate pathogenic Acanthamoeba effectively.PMID:35868573 | DOI:10.1016/j.exppara.2022.108330 (Source: Experimental Parasitology)
Source: Experimental Parasitology - July 22, 2022 Category: Parasitology Authors: Noor Akbar Ruqaiyyah Siddiqui Mustafa Khamis Taleb Ibrahim Naveed Ahmed Khan Source Type: research

A novel montmorillonite clay-cetylpyridinium chloride complex as a potential antiamoebic composite material in contact lenses disinfection
CONCLUSION: Given the ease of usage, safety, cost-effectiveness and long-term stability, CPC and CPC-Mt complex can prove to be an excellent choice in the rational development of contact-lens disinfectants to eradicate pathogenic Acanthamoeba effectively.PMID:35868573 | DOI:10.1016/j.exppara.2022.108330 (Source: Experimental Parasitology)
Source: Experimental Parasitology - July 22, 2022 Category: Parasitology Authors: Noor Akbar Ruqaiyyah Siddiqui Mustafa Khamis Taleb Ibrahim Naveed Ahmed Khan Source Type: research

A novel montmorillonite clay-cetylpyridinium chloride complex as a potential antiamoebic composite material in contact lenses disinfection
CONCLUSION: Given the ease of usage, safety, cost-effectiveness and long-term stability, CPC and CPC-Mt complex can prove to be an excellent choice in the rational development of contact-lens disinfectants to eradicate pathogenic Acanthamoeba effectively.PMID:35868573 | DOI:10.1016/j.exppara.2022.108330 (Source: Experimental Parasitology)
Source: Experimental Parasitology - July 22, 2022 Category: Parasitology Authors: Noor Akbar Ruqaiyyah Siddiqui Mustafa Khamis Taleb Ibrahim Naveed Ahmed Khan Source Type: research

A novel montmorillonite clay-cetylpyridinium chloride complex as a potential antiamoebic composite material in contact lenses disinfection
CONCLUSION: Given the ease of usage, safety, cost-effectiveness and long-term stability, CPC and CPC-Mt complex can prove to be an excellent choice in the rational development of contact-lens disinfectants to eradicate pathogenic Acanthamoeba effectively.PMID:35868573 | DOI:10.1016/j.exppara.2022.108330 (Source: Experimental Parasitology)
Source: Experimental Parasitology - July 22, 2022 Category: Parasitology Authors: Noor Akbar Ruqaiyyah Siddiqui Mustafa Khamis Taleb Ibrahim Naveed Ahmed Khan Source Type: research

Sensors, Vol. 22, Pages 5454: Wearable Travel Aids for Blind and Partially Sighted People: A Review with a Focus on Design Issues
h The ability to travel (independently) is very important for participation in education, work, leisure activities, and all other aspects of modern life. Blind and partially sighted people experience a number of barriers to travel, including inaccessible information and environments, and consequently require support from technology or other people to overcome them. Despite the potential of advanced technologies and the development of electronic travel aids, the long cane and guide dog remains the most commonly used solutions. Wearable technologies are becoming increasingly popular. They have the particular advantage of...
Source: Sensors - July 21, 2022 Category: Biotechnology Authors: Marion Hersh Tags: Review Source Type: research

New center in Phoenix set to transform immunotherapy
The University of Arizona ' s Center for Advanced Molecular and Immunological Therapies will support research to catalyze the next generation of precision health care treatments. Stacy Pigott Today University of Arizona Health Sciences05-cami_under_canopy-hero_1.jpg The Phoenix Bioscience Core will house the new Center for Advanced Molecular and Immunological Therapies, shown in this artist's rendering. The center will include space for academic and research activities, as well as collaboration spaces to serve academic, research and community needs.Campus NewsHealthBIO5Cancer CenterCollege of Medicine - TucsonNe...
Source: The University of Arizona: Health - July 7, 2022 Category: Universities & Medical Training Authors: mittank Source Type: research

HIV nucleoside reverse transcriptase inhibitors
Eur J Med Chem. 2022 Jun 20;240:114554. doi: 10.1016/j.ejmech.2022.114554. Online ahead of print.ABSTRACTMore than 40 years into the pandemic, HIV remains a global burden and as of now, there is no cure in sight. Fortunately, highly active antiretroviral therapy (HAART) has been developed to manage and suppress HIV infection. Combinations of two to three drugs targeting key viral proteins, including compounds inhibiting HIV reverse transcriptase (RT), have become the cornerstone of HIV treatment. This review discusses nucleoside reverse transcriptase inhibitors (NRTIs), including chain terminators, delayed chain terminator...
Source: European Journal of Medicinal Chemistry - July 6, 2022 Category: Chemistry Authors: Franck Amblard Dharmeshkumar Patel Eleftherios Michailidis Steven J Coats Mahesh Kasthuri Nicolas Biteau Zahira Tber Maryam Ehteshami Raymond F Schinazi Source Type: research