GSE245180 Comparative transcriptional analysis identifies genes associated with the attenuation of Theileria parva infected cells after long-term in vitro culture
Contributors : Elisabeth M van der Heijden ; Lucas Lefevre ; Anton Gossner ; Thomas Tzelos ; Tim Connelley ; Musa A HassanSeries Type : Expression profiling by high throughput sequencingOrganism : Bos taurus ; Theileria parvaAdministration of attenuated autologous Theileria parva infected cells can be used as an alternative to the infection-and-treatment method for inducing immunological protection against East Coast Fever. The mechanism of attenuation however has not been described. Using RNA sequencing, the transcriptomes of both host and parasite in uninfected (control), pathogenic (day 7 post-infection) and attenua...
Source: GEO: Gene Expression Omnibus - April 24, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Bos taurus Theileria parva Source Type: research

Co-transport behavior of Am(III) and natural colloids in the vadose zone sediments
This study provide new insights into the behavior of natural colloids carrying the Am(III) into aquifers through the vadose zone sediments.PMID:38641036 | DOI:10.1016/j.envpol.2024.124006 (Source: Environmental Pollution)
Source: Environmental Pollution - April 19, 2024 Category: Environmental Health Authors: Ke Chen Jun Zhu Qiulan Zhang Jingli Shao Yali Cui Aiming Zhang Tian Xie Source Type: research

Fe(II)-driven spatiotemporal assembly of heterotrophic and anammox bacteria enhances simultaneous nitrogen and phosphorus removal for low-strength municipal wastewater
This study provided a comprehensive sight into the function of Fe(Ⅱ) in mainstream PD/A process, and explored a promising alternative for synergetic nitrogen and phosphorus removal for low-strength municipal wastewater treatment.PMID:38641305 | DOI:10.1016/j.biortech.2024.130713 (Source: Bioresource Technology)
Source: Bioresource Technology - April 19, 2024 Category: Biotechnology Authors: Yongxing Chen Chuchu Zhang Zhenguo Chen Yuchun Yang Zhiman Lin Zexi Deng Xiaojun Wang Source Type: research

Association between maternal fasting glucose levels throughout pregnancy and preschoolers' refractive errors
CONCLUSIONS: High level of fasting plasma glucose trajectories during pregnancy has been observed to be associated with 6-year-old children's refractive error, hypermetropia and astigmatism. The first and the second trimesters may be critical periods for the effects of maternal blood glucose on children's vision. The long-term effect of maternal glucose metabolism on children's visual development deserves further study.PMID:38625056 | DOI:10.1210/clinem/dgae247 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 16, 2024 Category: Endocrinology Authors: Yufan Guo Jixing Zhou Jingru Lu Linlin Zhu Xuemei Hao Shuangqin Yan Juan Tong Shuman Tao Shaojun Xu Fangbiao Tao Kun Huang Source Type: research

Association between maternal fasting glucose levels throughout pregnancy and preschoolers' refractive errors
CONCLUSIONS: High level of fasting plasma glucose trajectories during pregnancy has been observed to be associated with 6-year-old children's refractive error, hypermetropia and astigmatism. The first and the second trimesters may be critical periods for the effects of maternal blood glucose on children's vision. The long-term effect of maternal glucose metabolism on children's visual development deserves further study.PMID:38625056 | DOI:10.1210/clinem/dgae247 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 16, 2024 Category: Endocrinology Authors: Yufan Guo Jixing Zhou Jingru Lu Linlin Zhu Xuemei Hao Shuangqin Yan Juan Tong Shuman Tao Shaojun Xu Fangbiao Tao Kun Huang Source Type: research

Balanced medial –lateral wall vs selective 3-wall orbital decompression for sight-threatening Graves’s orbitopathy: a clinical retrospective cohort study from 2016 to 2022
ConclusionsWe demonstrated that S3W-OD provides a lower rate of new-onset strabismus/diplopia as compared with BMLW-OD surgery, while still allowing for satisfactory visual outcomes.Trial registration number :  NCT05627401.  Date of registration: November 25, 2022. (Source: European Archives of Oto-Rhino-Laryngology)
Source: European Archives of Oto-Rhino-Laryngology - April 13, 2024 Category: ENT & OMF Source Type: research

Further delineation of phenotype and genotype of Kenny-Caffey syndrome type 2 (phenotype and genotype of KCS type 2)
CONCLUSION: We provide detailed characteristics of the largest KCS2 group in China and present the first genetically confirmed instance of father-to-daughter transmission of KCS2. Our study confirms that Arg569His is the hot spot variant and summarizes the typical phenotypes of KCS2, which would help early diagnosis and intervention.PMID:38591167 | PMC:PMC11002637 | DOI:10.1002/mgg3.2433 (Source: Molecular Medicine)
Source: Molecular Medicine - April 9, 2024 Category: Molecular Biology Authors: Xuefei Chen Chaochun Zou Source Type: research

Further delineation of phenotype and genotype of Kenny –Caffey syndrome type 2 (phenotype and genotype of KCS type 2)
ConclusionWe provide detailed characteristics of the largest KCS2 group in China and present the first genetically confirmed instance of father-to-daughter transmission of KCS2. Our study confirms that Arg569His is the hot spot variant and summarizes the typical phenotypes of KCS2, which would help early diagnosis and intervention. (Source: Molecular Genetics & Genomic Medicine)
Source: Molecular Genetics & Genomic Medicine - April 9, 2024 Category: Genetics & Stem Cells Authors: Xuefei Chen, Chaochun Zou Tags: ORIGINAL ARTICLE Source Type: research

Ischemia-inhibited ferric chelate reductase 1 improves ferroptosis-mediated intestinal ischemia injury via Hippo signaling
In conclusion, this study demonstrates that FRRS1 is intimately involved in the inhibition of ferroptosis and thus protection of the intestine from intestinal ischemia injury, its downstream mechanism was related to Hippo signaling. These data provide new sight for the prevention and treatment of intestinal ischemia injury.PMID:38531200 | DOI:10.1016/j.intimp.2024.111900 (Source: International Immunopharmacology)
Source: International Immunopharmacology - March 26, 2024 Category: Allergy & Immunology Authors: Pengzhen Liang Wei Xie Xing Wang Zhaohui Du Chuanming Zheng Hongchang Zhao Zhenjie Wang Zhong Ji Source Type: research

Ischemia-inhibited ferric chelate reductase 1 improves ferroptosis-mediated intestinal ischemia injury via Hippo signaling
In conclusion, this study demonstrates that FRRS1 is intimately involved in the inhibition of ferroptosis and thus protection of the intestine from intestinal ischemia injury, its downstream mechanism was related to Hippo signaling. These data provide new sight for the prevention and treatment of intestinal ischemia injury.PMID:38531200 | DOI:10.1016/j.intimp.2024.111900 (Source: International Immunopharmacology)
Source: International Immunopharmacology - March 26, 2024 Category: Allergy & Immunology Authors: Pengzhen Liang Wei Xie Xing Wang Zhaohui Du Chuanming Zheng Hongchang Zhao Zhenjie Wang Zhong Ji Source Type: research

Clinical phenotype of FOXP1 syndrome: parent-reported medical signs and symptoms in 40 individuals
Conclusion The results of this study may be used to further guide medical management and identify patient priorities for future research targeted on those features of FOXP1 syndrome that most impair quality of life of patients and their families. (Source: Journal of Medical Genetics)
Source: Journal of Medical Genetics - March 21, 2024 Category: Genetics & Stem Cells Authors: Koene, S., Ropers, F. G., Wieland, J., Rybak, T., Wildschut, F., Berghuis, D., Morgan, A., Trelles, M. P., Scheepe, J. R., Bökenkamp, R., Peeters-Scholte, C. M. P. C. D., Braden, R., Santen, G. W. E. Tags: Phenotypes Source Type: research

Prevalence of strabismus and risk factors in adults born preterm with and without retinopathy of prematurity: results from the Gutenberg Prematurity Eye study
CONCLUSION: Low GA and refraction of the eye are independent risk factors for strabismus, which typically occurs in the first 10 years of life. Perinatal adverse events are the most important factors for the presence of nystagmus in adulthood.PMID:38503479 | DOI:10.1136/bjo-2023-324698 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - March 19, 2024 Category: Opthalmology Authors: Achim Fie ß Kim Dautzenberg Sandra Gi ßler Eva Mildenberger Michael S Urschitz Heike M Elflein Panagiotis Laspas Bernhard M Stoffelns Norbert Pfeiffer Alexander K Schuster Source Type: research

Prevalence of strabismus and risk factors in adults born preterm with and without retinopathy of prematurity: results from the Gutenberg Prematurity Eye study
CONCLUSION: Low GA and refraction of the eye are independent risk factors for strabismus, which typically occurs in the first 10 years of life. Perinatal adverse events are the most important factors for the presence of nystagmus in adulthood.PMID:38503479 | DOI:10.1136/bjo-2023-324698 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - March 19, 2024 Category: Opthalmology Authors: Achim Fie ß Kim Dautzenberg Sandra Gi ßler Eva Mildenberger Michael S Urschitz Heike M Elflein Panagiotis Laspas Bernhard M Stoffelns Norbert Pfeiffer Alexander K Schuster Source Type: research

Skeletal expansion via craniofacial distraction osteogenesis technique in syndromic craniosynostosis: impact on ophthalmic parameters
ConclusionOur study shows a significant increase in orbital volume post-surgery with a reduction in the degree of proptosis. Optic disc and nerve health improved after the surgery. Changes in terms of visual acuity, refractive error and IOP were inconsistent after the surgical intervention. (Source: International Ophthalmology)
Source: International Ophthalmology - March 19, 2024 Category: Opthalmology Source Type: research

Sensors, Vol. 24, Pages 1959: An Efficient Convolutional Denoising Autoencoder-Based BDS NLOS Detection Method in Urban Forest Environments
ming Wang The BeiDou Navigation Satellite System (BDS) provides real-time absolute location services to users around the world and plays a key role in the rapidly evolving field of autonomous driving. In complex urban environments, the positioning accuracy of BDS often suffers from large deviations due to non-line-of-sight (NLOS) signals. Deep learning (DL) methods have shown strong capabilities in detecting complex and variable NLOS signals. However, these methods still suffer from the following limitations. On the one hand, supervised learning methods require labeled samples for learning, which inevitably encounters ...
Source: Sensors - March 19, 2024 Category: Biotechnology Authors: Yahang Qin Zhenni Li Shengli Xie Haoli Zhao Qianming Wang Tags: Article Source Type: research