Hypermetropia (long sighted) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

How patients experience thyroid eye disease
CONCLUSIONS: Physical manifestations of TED impact QoL for patients through all phases of the disease. It is essential that physicians and healthcare professionals become more familiar with patient experiences such as those described here to better help patients manage their disease.PMID:38027128 | PMC:PMC10665908 | DOI:10.3389/fendo.2023.1283374 (Source: Pain Physician)
Source: Pain Physician - November 29, 2023 Category: Anesthesiology Authors: Terry J Smith Laszlo Heged üs Ira Lesser Petros Perros Kimberly Dorris Michele Kinrade Patti Troy-Ott Laura Wuerth Mukund Nori Source Type: research

Application of patient-derived induced pluripotent stem cells and organoids in inherited retinal diseases
Stem Cell Res Ther. 2023 Nov 27;14(1):340. doi: 10.1186/s13287-023-03564-5.ABSTRACTInherited retinal diseases (IRDs) can induce severe sight-threatening retinal degeneration and impose a considerable economic burden on patients and society, making efforts to cure blindness imperative. Transgenic animals mimicking human genetic diseases have long been used as a primary research tool to decipher the underlying pathogenesis, but there are still some obvious limitations. As an alternative strategy, patient-derived induced pluripotent stem cells (iPSCs), particularly three-dimensional (3D) organoid technology, are considered a ...
Source: Cell Research - November 28, 2023 Category: Cytology Authors: Yuqin Liang Xihao Sun Chunwen Duan Shibo Tang Jiansu Chen Source Type: research

New sights of low dose IL-2: Restoration of immune homeostasis for viral infection
In conclusion, focusing on the role of ld-IL-2 in viral infections may provide a new perspective for regulating immune responses following viral infections and improving prognosis.PMID:37985960 | DOI:10.1111/imm.13719 (Source: Immunology)
Source: Immunology - November 21, 2023 Category: Allergy & Immunology Authors: Rui Su Tingting Zhang Hui Wang Gaofei Yan Ruihe Wu Xin Zhang Chong Gao Xiaofeng Li Caihong Wang Source Type: research

How big is too big? Bat ’s enormous penis makes penetration impossible
If you go out walking at dusk nearly anywhere in Europe or Asia, you’re likely to catch a glimpse of a serotine bat ( Eptesicus serotinus ) in flight. These furry creatures are a familiar sight, known to roost in chimneys and in the gables of old churches. But although serotine bats are quite common, scientists have yet to unravel all their mysteries. In fact, up until recently, the male of this species was hiding a truly astonishing secret: a penis so large that it makes “traditional” sex impossible. “People have always wondered why bats have such large penises,” says Brock Fenton, a biologist at...
Source: Science of Aging Knowledge Environment - November 20, 2023 Category: Geriatrics Source Type: research

Transcriptome sequencing and microRNA –mRNA regulatory network construction in the lens from a Na2SeO3-induced Sprague Dawley rat cataract model
This study aimed to explore the regulatory mechanism of age-related cataract (ARC) formation and progression. (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - November 16, 2023 Category: Opthalmology Authors: Rui Fang, Pei-Lin Yue, Hai-Long Li, Xue-Fei Ding, Yu-Xuan Jia, Zhao-Chuan Liu, Hong-Gang Zhou and Xu-Dong Song Tags: Research Source Type: research

Satellite images bring Serbia ’s hidden Bronze Age megastructures to light
More than 3000 years ago during the Bronze Age, people across Eurasia formed massive trade networks that tied the continent together. But the Pannonian Plain, an open expanse that today includes parts of Romania, Hungary, and Serbia, was considered a relative hinterland. That was true even after archaeologists 2 decades ago uncovered a handful of massive Bronze Age enclosures, some protected by walls and ditches many kilometers long. No one was sure how the structures were tied to cultural developments elsewhere in Europe, although scattered finds of bronze artifacts showed the enclosures weren’t completely isolate...
Source: Science of Aging Knowledge Environment - November 14, 2023 Category: Geriatrics Source Type: research

Nurse ethicists: Innovative resource or ideological aspiration?
Nurs Ethics. 2023 Aug;30(5):680-687. doi: 10.1177/09697330231191817.ABSTRACTIn recent years, there have been growing calls for nurses to have a formal advanced practice role as nurse ethicists in hospital contexts. Initially proposed in the cultural context of the USA where nurse ethicists have long been recognised, the idea is being advocated in other judications outside of the USA such as the UK, Australia and elsewhere. Such calls are not without controversy, however. Underpinning this controversy are ongoing debates about the theoretical, methodological and political dimensions of clinical ethics support services gener...
Source: Nursing Ethics - November 10, 2023 Category: Nursing Authors: Megan-Jane Johnstone Source Type: research

How patients experience thyroid eye disease
ConclusionsPhysical manifestations of TED impact QoL for patients through all phases of the disease. It is essential that physicians and healthcare professionals become more familiar with patient experiences such as those described here to better help patients manage their disease. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - November 9, 2023 Category: Endocrinology Source Type: research

The role of N6-methyladenosine methylation in PAHs-induced cancers
Environ Sci Pollut Res Int. 2023 Nov 4. doi: 10.1007/s11356-023-30710-6. Online ahead of print.ABSTRACTPolycyclic aromatic hydrocarbons (PAHs), which are a wide range of environmental toxicants, may act on humans through inhalation, ingestion, and skin contact, resulting in a range of toxic reactions. Epidemiological studies showed that long-term exposure to PAHs in the occupational and living environment results in a substantial rise in the incidence rate of many cancers in the population, so the prevention and treatment of these diseases have become a major worldwide public health problem. N6-methyladenosine (m6A) modifi...
Source: Environmental Science and Pollution Research International - November 4, 2023 Category: Environmental Health Authors: Yujie Wei Xiaona Guo Lifeng Li Wenhua Xue Longhao Wang Chengxin Chen Shilong Sun Yaqi Yang Wu Yao Wei Wang Jie Zhao Xiaoran Duan Source Type: research

Achromatopsia: Long term visual performance and clinical characteristics
CONCLUSIONS: CNGA3 is the main gene associated with achromatopsia in our population (around ∼ 73%), which is in contrast to the distribution worldwide (∼ 25%). Most achromats suffer from photophobia and nystagmus, and the main refractive error is hypermetropia. Achromatopsia's natural course seems to be stationary, and there may even be a slight improvement in visual acuity with time.PMID:37920903 | DOI:10.1177/11206721231212768 (Source: European Journal of Ophthalmology)
Source: European Journal of Ophthalmology - November 3, 2023 Category: Opthalmology Authors: Yuval Margherita Eshel Ora Abaev Claudia Yahalom Source Type: research

Mice thrive at 6700 meters up —higher than any mammals were thought able to live
Few places are as inhospitable as the top of Llullaillaco, a 6700-meter volcano on the border between Chile and Argentina. Winds howl nonstop and no plants live there; daytime temperatures never get above freezing and plummet even more come nightfall. Oxygen levels are just 40% of those at sea level, too low for mammals to live there —or so biologists thought until 3 years ago when a research team captured a live leaf-eared mouse at its summit. Now new work shows this animal was not a fluke. The team has found other leaf-eared mice on additional volcano tops, and genomic studies of these summit dwellers and their lower e...
Source: Science of Aging Knowledge Environment - October 23, 2023 Category: Geriatrics Source Type: research