Hypermetropia (long sighted) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Novel sights on therapeutic, prognostic, and diagnostics aspects of non-coding RNAs in glioblastoma multiforme
AbstractGlioblastoma Multiforme (GBM) is the primary brain tumor and accounts for 200,000 deaths each year worldwide. The standard therapy includes surgical resection followed by temozolomide (TMZ)-based chemotherapy and radiotherapy. The survival period of GBM patients is only 12 –15 months. Therefore, novel treatment modalities for GBM treatment are urgently needed. Mounting evidence reveals that non-coding RNAs (ncRNAs) were involved in regulating gene expression, the pathophysiology of GBM, and enhancing therapeutic outcomes. The combinatory use of ncRNAs, chemotherape utic drugs, and tumor suppressor gene expressio...
Source: Metabolic Brain Disease - July 21, 2023 Category: Neurology Source Type: research

Ocular manifestations of congenital anomalies of the kidney and urinary tract (CAKUT)
This study reviewed diseases associated with the Genomics England CAKUT-associated gene panel for ocular anomalies. In addition, each gene was examined for expression in the human retina and an ocular phenotype in mouse model s using the Human Protein Atlas and Mouse Genome Informatics databases, respectively. Thirty-four (54%) of the 63 CAKUT-associated genes (55 ‘green’ and 8 ‘amber’) had a reported ocular phenotype. Five of the 6 most common CAKUT-associated genes (PAX2,EYA1,SALL1,GATA3,PBX1) that represent 30% of all diagnoses had ocular features. The ocular abnormalities found with most CAKUT-associated genes...
Source: Pediatric Nephrology - July 20, 2023 Category: Urology & Nephrology Source Type: research

Novel sights on therapeutic, prognostic, and diagnostics aspects of non-coding RNAs in glioblastoma multiforme
AbstractGlioblastoma Multiforme (GBM) is the primary brain tumor and accounts for 200,000 deaths each year worldwide. The standard therapy includes surgical resection followed by temozolomide (TMZ)-based chemotherapy and radiotherapy. The survival period of GBM patients is only 12 –15 months. Therefore, novel treatment modalities for GBM treatment are urgently needed. Mounting evidence reveals that non-coding RNAs (ncRNAs) were involved in regulating gene expression, the pathophysiology of GBM, and enhancing therapeutic outcomes. The combinatory use of ncRNAs, chemotherape utic drugs, and tumor suppressor gene expressio...
Source: Metabolic Brain Disease - July 15, 2023 Category: Neurology Source Type: research

Combined central serous chorioretinopathy, hypermetropia, short axial length, chorioretinal folds, enlarged/thickened ocular coats, with varying association of scleral changes (CHAFES)
To describe a condition with the following features: chronic central serous chorioretinopathy (CCSC), chorioretinal folds, scleral changes (including any of the following flattened or ‘squared off’ posterior p... (Source: BMC Ophthalmology)
Source: BMC Ophthalmology - July 14, 2023 Category: Opthalmology Authors: Susan M Downes, Sonia P Mall, Saoud Al-Khuzaei, Rasmeet Chadha, Andrew Gibson, Victor Chong and Alan C. Bird Tags: Case Report Source Type: research

Seeing color following gene augmentation therapy in achromatopsia
Curr Biol. 2023 Jul 3:S0960-9822(23)00826-6. doi: 10.1016/j.cub.2023.06.041. Online ahead of print.ABSTRACTHow will people who spent their visual lives with only rods respond to cone function restoration? Will they be able suddenly see the colors of the rainbow? CNGA3-achromatopsia is a congenital hereditary disease in which cone dysfunction leads patients to have rod photoreceptor-driven vision only in daylight,1,2,3,4 seeing the world in blurry shades of gray.5,6 We studied color perception in four CNGA3-achromatopsia patients following monocular retinal gene augmentation therapy.7,8,9 Following treatment, although some ...
Source: Current Biology - July 11, 2023 Category: Biology Authors: Ayelet McKyton Devora Marks Ohana Einav Nahmany Eyal Banin Netta Levin Source Type: research

This amateur astronomer may be the world ’s top supernova hunter
For Koichi Itagaki, it was just another evening of supernova hunting. After his usual 7 p.m. dinner with his wife, he drove to his private observatory in the hills above his home in Yamagata, Japan, 290 kilometers north of Tokyo. He set out treats for the only visitors he allows on his celestial patrols: a stray cat he calls Nora and the raccoon dogs that warily approach from the surrounding forest. He then took a seat within his “headquarters,” a cozy hut equipped with a bed, minifridge, microwave—and a dozen monitors used to control seven telescopes at three locations across Japan. On clear nights, each tele...
Source: Science of Aging Knowledge Environment - July 6, 2023 Category: Geriatrics Source Type: research

How did COVID-19 affect acute urolithiasis? An inner Anatolian experience
CONCLUSION: The COVID-19 pandemic resulted in neither sicker nor fewer patients suffering from acute ureteric colic in the ES.PMID:37409918 | DOI:10.14744/tjtes.2023.36067 (Source: Turkish Journal of Trauma and Emergency Surgery : TJTES)
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - July 6, 2023 Category: Emergency Medicine Authors: İbrahim Üntan Source Type: research