The 2023 Dengue Outbreak in Bangladesh: Exploring the Epidemiology in Hospitalized Patients
We report that a substantial number of patients developed severe dengue during the epidemic in 2023, and provide detailed clinical-epidemiological profiles of the patients, offering valuable insight into management of dengue cases.PMID:38593789 | DOI:10.4269/ajtmh.23-0806 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 9, 2024 Category: Tropical Medicine Authors: Urby Saraf Anika Muna Islam Fatema E Nur Mou Mrinal Saha Aparna Deb Rubaiya Rahman Tui Joarder Rakeen Manzoor Afroza Jesmin Ayesha Martuja Jannatul Fardous Mohiuddin Sharif Md Abdur Rafi Mohammad Jahid Hasan Source Type: research

Cost-effectiveness of rimegepant oral lyophilisate compared to best supportive care for the acute treatment of migraine in the UK
CONCLUSION: This study highlights the economic value of rimegepant which was found to be cost-effective for the acute treatment of migraine in adults unsuitable for triptans.PMID:38590236 | DOI:10.1080/13696998.2024.2340932 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 9, 2024 Category: Health Management Authors: Karissa Johnston Lauren C Powell Evan Popoff Gil J L'Italien Robert Pawinski Aideen Ahern Sam Large Thang Tran Aaron Jenkins Source Type: research

Evaluation and Treatment of Patients with Small Posterior Cranial Fossa and Chiari Malformation, Types 0 and 1
Adv Tech Stand Neurosurg. 2024;50:307-334. doi: 10.1007/978-3-031-53578-9_11.ABSTRACTThe diagnosis of Chiari I malformation is straightforward in patients with typical signs and symptoms of Chiari I malformation and magnetic resonance imaging (MRI) confirming ≥5 mm of cerebellar tonsillar ectopia, with or without a syrinx. However, in many cases, Chiari I malformation is discovered incidentally on MRI to evaluate global headache, cervical radiculopathy, or other conditions. In those cases, the clinician must consider if cerebellar tonsillar ectopia is related to the presenting symptoms. Surgical decompression of the cere...
Source: Advances and Technical Standards in Neurosurgery - April 9, 2024 Category: Neurosurgery Authors: Enver I Bogdanov John D Heiss Source Type: research

Cost-effectiveness of rimegepant oral lyophilisate compared to best supportive care for the acute treatment of migraine in the UK
CONCLUSION: This study highlights the economic value of rimegepant which was found to be cost-effective for the acute treatment of migraine in adults unsuitable for triptans.PMID:38590236 | DOI:10.1080/13696998.2024.2340932 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - April 9, 2024 Category: Health Management Authors: Karissa Johnston Lauren C Powell Evan Popoff Gil J L'Italien Robert Pawinski Aideen Ahern Sam Large Thang Tran Aaron Jenkins Source Type: research

Acquired methemoglobinemia due to nitrobenzene poisoning: An unusual acquaintance
Key Clinical MessageNitrobenzene poisoning is a rare yet life-threatening contention. The ensuing acute methemoglobinemia has a high fatality rate, hence early prompt intervention is required. Methylene blue (intravenous or oral) and ascorbic acid are the cornerstones of management. They must be administered to suspected patients without tardiness.AbstractAn aromatic organic chemical used in paints and the printing industry is nitrobenzene. Its poisoning causes potentially fatal methemoglobinemia. One aspect of its management involves reducing the iron moiety from its ferric to ferrous form by administering intravenous met...
Source: Clinical Case Reports - April 9, 2024 Category: General Medicine Authors: Sunil Bhatta, Pusp Raj Awasthi Tags: CASE REPORT Source Type: research

The association between dietary glycemic index and disease severity among the women with episodic migraine
. (Source: Nutritional Neuroscience)
Source: Nutritional Neuroscience - April 9, 2024 Category: Nutrition Authors: Vajiheh ArabshahiMansoureh ToghaFaezeh Khorshaa Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iranb Department of Neurology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iranc Headache Depa Source Type: research

Pharmacogenomic study—A pilot study of the effect of pharmacogenomic phenotypes on the adequate dosing of verapamil for migraine prevention
The Pharmacogenomics Journal, Published online: 09 April 2024; doi:10.1038/s41397-024-00331-4Pharmacogenomic study—A pilot study of the effect of pharmacogenomic phenotypes on the adequate dosing of verapamil for migraine prevention (Source: The Pharmacogenomics Journal)
Source: The Pharmacogenomics Journal - April 9, 2024 Category: Drugs & Pharmacology Authors: Yi-Chieh Chen Han Wang Jayawant N. Mandrekar Carrie E. Robertson Amaal J. Starling Fred M. Cutrer Chia-Chun Chiang Source Type: research

Blood vessel organoids generated by base editing and harboring single nucleotide variation in Notch3 effectively recapitulate CADASIL-related pathogenesis
In this study, we focused onin vitro modeling and therapeutic target finding of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), the most common form of hereditary stroke disorder caused by mutations in the NOTCH3 gene. Despite the identification of these mutations, the underlying pathological mechanism is elusive, and effective therapeutic approaches are lacking. CADASIL primarily affects the blood vessels in the brain, leading to ischemic strokes, migraines, and dementia. By employing CRISPR/Cas9 base-editing technology, we generated human induced pluripotent stem cell...
Source: Molecular Neurobiology - April 9, 2024 Category: Neurology Source Type: research

Analysis of Acupoint Selection Rules for Guasha Treatment of Primary Headaches Based on Data Mining
(Source: Journal of Pain Research)
Source: Journal of Pain Research - April 8, 2024 Category: Anesthesiology Tags: Journal of Pain Research Source Type: research

Self-reported Side Effects of SARS-CoV-2 Vaccination
Acta Medica (Hradec Kralove). 2023;66(4):154-157. doi: 10.14712/18059694.2024.10.ABSTRACTSARS-CoV-2 vaccines are often promoted as safe. However, real world data tell a different story. The aim of this study is to investigate the type and frequency of adverse reactions to SARS-CoV-2 vaccination in a randomly selected cohort of unrelated individuals. Adverse reactions to the first/second dose of a SARS-CoV-2 vaccine were recorded using an online reporting system called "Pabbly". Patients were asked via social media to report any symptoms temporarily associated with vaccination. One hundred subjects were enrolled. The mean a...
Source: Acta Medica: Hradec Kralove - April 8, 2024 Category: General Medicine Authors: Josef Finsterer Danice Hertz Source Type: research

Myofascial Release for the Treatment of Tension-Type, Cervicogenic Headache or Migraine: A Systematic Review and Meta-Analysis
CONCLUSION: The meta-analysis results indicate that MFR intervention can significantly alleviate pain and disability in TTH and CGH. For migraine, however, the results were inconsistent, and there was only moderate quality evidence of disability improvement for TTH and CGH. In contrast, the quality of other evidence was low or very low.PMID:38585645 | PMC:PMC10999287 | DOI:10.1155/2024/2042069 (Source: Pain Research and Management)
Source: Pain Research and Management - April 8, 2024 Category: Anesthesiology Authors: Zhoupeng Lu Hui Zou Peng Zhao Jialin Wang Ruirui Wang Source Type: research

Myofascial Release for the Treatment of Tension-Type, Cervicogenic Headache or Migraine: A Systematic Review and Meta-Analysis
CONCLUSION: The meta-analysis results indicate that MFR intervention can significantly alleviate pain and disability in TTH and CGH. For migraine, however, the results were inconsistent, and there was only moderate quality evidence of disability improvement for TTH and CGH. In contrast, the quality of other evidence was low or very low.PMID:38585645 | PMC:PMC10999287 | DOI:10.1155/2024/2042069 (Source: Pain Research and Management)
Source: Pain Research and Management - April 8, 2024 Category: Anesthesiology Authors: Zhoupeng Lu Hui Zou Peng Zhao Jialin Wang Ruirui Wang Source Type: research

Self-reported Side Effects of SARS-CoV-2 Vaccination
Acta Medica (Hradec Kralove). 2023;66(4):154-157. doi: 10.14712/18059694.2024.10.ABSTRACTSARS-CoV-2 vaccines are often promoted as safe. However, real world data tell a different story. The aim of this study is to investigate the type and frequency of adverse reactions to SARS-CoV-2 vaccination in a randomly selected cohort of unrelated individuals. Adverse reactions to the first/second dose of a SARS-CoV-2 vaccine were recorded using an online reporting system called "Pabbly". Patients were asked via social media to report any symptoms temporarily associated with vaccination. One hundred subjects were enrolled. The mean a...
Source: Acta Medica: Hradec Kralove - April 8, 2024 Category: General Medicine Authors: Josef Finsterer Danice Hertz Source Type: research